Material Safety Data Sheet: 1-Carboxymethyl-Pyridinium Bromide

Identification

Product Name: 1-Carboxymethyl-Pyridinium Bromide
Synonyms: No common synonyms found
Chemical Formula: C7H8BrNO2
Recommended Uses: Laboratory reagent, intermediate in organic synthesis
Manufacturer: Specify supplier's contact details for emergencies
CAS Number: 872-82-6
Emergency Phone: Confirm emergency contact with designated supplier
Contact Address: Typically found on the original container label

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal, inhalation), irritant to skin and eyes
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory symptoms, harmful if swallowed
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, wear appropriate PPE
Target Organs: Mucous membranes, gastrointestinal tract, respiratory system
Routes of Entry: Inhalation, ingestion, skin and eye contact

Composition / Information on Ingredients

Chemical: 1-Carboxymethyl-Pyridinium Bromide
Concentration: 98-100% (pure substance)
Impurities: Trace byproducts from synthesis, typically pyridine derivatives below 0.5%
Molecular Weight: 218.05 g/mol

First Aid Measures

General Advice: Remove victim from exposure, seek medical attention if feeling unwell
Inhalation: Move to fresh air, keep patient comfortable, consult medical support
Skin Contact: Take off contaminated clothing, rinse skin with plenty of water, seek help if redness or irritation develops
Eye Contact: Rinse cautiously with water for several minutes, keep eyelids apart, remove contact lenses, get medical attention
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, call a physician
Acute Symptoms: Redness, irritation, dizziness, respiratory discomfort
Delayed Effects: Sensitization or dermatitis possible after repeated exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Specific Hazards: Emits toxic fumes of nitrogen oxides, bromine compounds under fire conditions
Protective Equipment: Self-contained breathing apparatus, full protective gear
Thermal Decomposition Products: Nitrogen oxides, hydrogen bromide, carbon oxides
Advice for Firefighters: Prevent runoff from contaminating soil or waterways, avoid inhaling combustion gases

Accidental Release Measures

Personal Precautions: Use chemical-resistant gloves, goggles, and lab coat, limit access to the spill area
Environmental Protection: Prevent material from entering drains or watercourses, notify authorities if contamination occurs
Methods for Cleanup: Sweep up with minimal dust, collect in a labeled container for disposal, ventilate affected area
Further Handling: Decontaminate tools and surfaces with detergent and water

Handling and Storage

Safe Handling: Avoid skin and eye contact, use only in well-ventilated areas, do not eat or drink during use
Storage Conditions: Keep tightly sealed in original container, store in a cool and dry location, segregate from incompatible materials
Incompatibilities: Strong oxidizers, reducing agents, acids and bases
Specific Precautions: Clearly label all storage containers, keep away from direct sunlight and moisture

Exposure Controls and Personal Protection

Exposure Limits: No established exposure limits; minimize dust and vapors
Engineering Controls: Use fume hood or local exhaust ventilation, provide emergency eyewash and showers in work area
Personal Protective Equipment (PPE): Safety glasses or goggles, impermeable gloves, lab coat, NIOSH-approved respirator if dust forms
Hygiene Measures: Wash hands after handling, remove soiled clothing, avoid contact with skin and eyes

Physical and Chemical Properties

Appearance: White to light yellow crystalline powder
Odor: No significant odor
Odor Threshold: Not determined
pH: Not available (aqueous solutions show slight acidity)
Melting Point: 190-200°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Soluble in water, moderately soluble in polar organic solvents
Vapor Pressure: Not significant at room temperature
Vapor Density: Not determined
Specific Gravity: 1.5-1.7 (estimated)
Flash Point: Not flammable under standard conditions
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: >190°C
Viscosity: Not relevant (solid at room temperature)

Stability and Reactivity

Chemical Stability: Stable under recommended conditions
Reactivity: May react with strong oxidizers and strong acids or bases
Conditions to Avoid: Heat, moisture, sunlight, incompatible chemicals
Hazardous Decomposition: Hydrogen bromide, nitrogen oxides, carbon oxides during thermal decomposition
Polymerization: Not expected under normal conditions
Incompatible Materials: Strong reducing agents, highly reactive compounds

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin, eyes
Acute Effects: Irritation to eyes, skin, mucous membranes; possible respiratory tract irritation
Chronic Effects: Prolonged exposure may trigger dermatitis or sensitization
LD50 (Oral): Not specifically determined; likely in the range for similar pyridinium compounds (rat: 300-2000 mg/kg)
Carcinogenicity: No identified carcinogenic effects for this compound in available literature
Mutagenicity: Not reported
Reproductive Toxicity: Data not available
Symptoms: Redness, itching, coughing, nausea, abdominal pain

Ecological Information

Ecotoxicity: Avoid release to the environment; not classified, but similar compounds affect aquatic organisms
Persistence and Degradability: Expected to degrade slowly in soil and water
Bioaccumulative Potential: Not expected to bioaccumulate significantly
Mobility in Soil: Moderate mobility related to water solubility
Other Adverse Effects: Considered hazardous to aquatic life in concentrated spills
Aquatic Toxicity: Data not established, prudent to avoid release

Disposal Considerations

Disposal Methods: Dispose of contents/container in accordance with local, regional, national, and international regulations
Handling Waste: Label waste containers clearly, keep separate from general waste, use licensed chemical disposal company
Contaminated Packaging: Rinse before disposal or recycle if permitted, treat as hazardous waste
Precautions: Avoid contamination of soil, drains, and surface waters

Transport Information

UN Number: Not classified as hazardous for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class(es): N/A
Packing Group: N/A
Marine Pollutant: Not listed
Special Precautions: Use secure, labeled containers; transport with documentation
Other Requirements: Protect against physical damage and moisture during transport

Regulatory Information

TSCA Status: Listed or notified
EINECS/ELINCS: Registered
OSHA: Not specifically regulated
SARA Title III: Not subject to reporting
REACH: Pre-registered or fully registered within the EU
WHMIS (Canada): Classified as hazardous material
Other Regulations: Adhere to local, regional, and national guidelines for safe chemical handling