Product Name: 1-Ethyl-2,3-Dimethylimidazolium Ethylsulfate
CAS Number: 342573-75-5
EC Number: 610-106-2
Recommended Use: Laboratory chemicals, research and development, ionic liquids applications in synthesis and electrochemistry
Manufacturer Information: Supplier contact details typically include name, address, and emergency phone line; in practice, always keep handy up-to-date local poison control center contact.
Synonyms: [EMIM][EtSO4], 1-ethyl-2,3-dimethylimidazolium ethyl sulfate
Emergency Overview: Colorless to pale yellow liquid, faint characteristic odor, non-volatile, hydrophilic ionic liquid, not highly flammable but certain hazards present.
GHS Classification: Skin Irritation Category 2, Eye Irritation Category 2A, Acute Toxicity—Oral Category 4
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed.
Pictograms: Exclamation mark
Precautionary Statements: Wear protective gloves, eye/face protection; avoid breathing vapors; wash exposed skin thoroughly after handling.
Potential Health Effects: Skin contact may result in redness and irritation; eye exposure may cause tearing, redness, blurred vision; swallowing material can produce discomfort; inhaling vapors, particularly in poorly ventilated settings, may cause dizziness, mild respiratory irritation.
Chemical Identity: 1-Ethyl-2,3-dimethylimidazolium ethylsulfate
Chemical Formula: C9H18N2O4S
Component: 1-ethyl-2,3-dimethylimidazolium cation (C7H13N2+)
Component: Ethylsulfate anion (C2H5SO4–)
Purity: ≥ 95% (typical for research grade)
Impurities: Trace imidazolium by-products, trace ethyl sulfate derivatives, water content (as moisture), each typically less than 1% in well-handled materials.
Additives: No intentional additives in standard chemical offerings; always check supplier certificate of analysis.
Inhalation: Move person to fresh air as soon as possible; keep warm and at rest; if symptoms like cough, dizziness, or shortness of breath persist, seek medical attention.
Skin Contact: Wash skin immediately with plenty of running water and soap; remove contaminated clothing and shoes; persistent redness or irritation warrants a visit to a healthcare provider.
Eye Contact: Rinse eyes cautiously with lukewarm running water for several minutes; hold eyelids open; avoid rubbing; call doctor if pain, redness, or blurred vision does not clear up quickly.
Ingestion: Rinse mouth, do not induce vomiting; give water if the person is fully conscious; seek medical attention for nausea, pain, or persistent symptoms.
Advice to Physician: Treat symptomatically and provide any supportive therapies as needed; no specific antidote documented.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide; avoid high-pressure stream which might splash material.
Specific Hazards: Combustibles present in decomposed vapors such as carbon oxides, nitrogen oxides, sulfur oxides may form at high temperature.
Protective Equipment: Firefighters should use full protective clothing and self-contained breathing apparatus; avoid inhaling decomposition products.
Firefighting Instructions: Control run-off water to avoid contamination of drains and watercourses; use standard fire-fighting tactics to keep containers cool with water spray.
Explosion Data: Not considered explosive; static discharge precautions recommended in fine mist or vapor situation near ignition sources.
Personal Precautions: Wear appropriate personal protective equipment, including gloves, chemical splash goggles, and lab coat; ensure area is well-ventilated.
Environmental Precautions: Keep spills and contaminated rinse water out of the municipal sewage system; prevent product from entering drains, surface water, and groundwater.
Cleanup Methods: Absorb with inert material such as sand or diatomaceous earth; transfer carefully into labeled disposal container; wash area with plenty of water.
Spill Response Team: For larger leaks, assign trained personnel to wear chemical splash suit and respiratory protection.
Waste Disposal: Clean waste as hazardous according to local regulations; do not mix with incompatible chemicals.
Precautions for Safe Handling: Avoid unnecessary skin contact, ingestion, or inhalation; use only with adequate ventilation; do not eat, drink, or smoke while handling material; clean up spills promptly.
Storage Conditions: Store tightly closed in a cool, dry, dry, ventilated place away from strong oxidizing agents, acids, bases, reducing agents.
Container Material: Use original chemical-resistant shipping and storage containers; avoid containers with low chemical resistance such as soft plastics.
Incompatibilities: Keep away from materials prone to oxidation or acid/base hydrolysis.
Storage Life: Well-sealed, stable in storage for up to two years under recommended conditions; always check certificate of analysis or shelf-life tag before use.
Engineering Controls: Use fume hood or provide local exhaust ventilation at points of vapor or mist release; monitor air concentrations if working with high quantities.
Threshold Limit Values: No specific occupational exposure limits established; minimize exposure through best-practice laboratory hygiene and handling controls.
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), full-length lab coat, closed shoes, chemical safety goggles or face shield for splash risk.
Respiratory Protection: Respiratory protection with organic vapor cartridges for procedures generating mists or vapors.
Hygiene Measures: Wash hands and any exposed skin after handling; avoid contact with food, drinks, or cigarettes during use.
Appearance: Colorless to pale yellow viscous liquid
Odor: Faint, mild characteristic
Odor Threshold: Not determined
pH: Approximate 5-8 in 10% aqueous solution
Melting Point / Freezing Point: Typically below -20°C
Boiling Point / Range: Decomposes before boiling, typically over 250°C
Flash Point: >140°C (closed cup testing sample)
Evaporation Rate: Negligible (non-volatile)
Flammability: Not easily ignitable under normal lab conditions
Explosion Limits: Not established
Vapor Pressure: Not significant at room temperature
Vapor Density: Not established
Relative Density: 1.18 – 1.25 g/cm³ at 20°C
Solubility: Miscible with water, alcohols; limited solubility in hydrocarbons
Partition Coefficient: Not measured, presumed low octanol-water partition
Autoignition Temperature: Not measured
Decomposition Temperature: Degrades above 250°C
Viscosity: Viscous at room temperature, typically 70–110 cP at 25°C
Molecular Weight: 250.31 g/mol
Chemical Stability: Stable under recommended conditions of storage and handling; no hazardous polymerization expected.
Reactivity: Avoid strong oxidizing agents, strong acids, and alkali; slow hydrolysis possible at extreme pH values.
Thermal Decomposition: Produces carbon dioxide, nitrogen oxides, sulfur oxides, hydrocarbons on heating above decomposition.
Incompatibilities: Reacts with powerful oxidizers or strong bases to liberate heat and possible hazardous vapors.
Hazardous Reactions: None expected in routine use under standard laboratory precautions.
Corrosivity: Not considered corrosive to metals or lab surfaces at neutral pH.
Likely Routes of Exposure: Skin and eye contact, ingestion, inhalation of vapors or mists
Acute Toxicity: Data from related imidazolium compounds suggest oral LD50 (rat) typically in 1000–2000 mg/kg range; not considered highly toxic but ingestion should always be avoided.
Eye Effects: Causes moderate to severe irritation, tearing, and potential temporary injury.
Skin Effects: Irritation, redness, local discomfort possible after direct contact.
Inhalation Effects: May irritate the membranes of nose, throat, lungs with cough or mild dizziness after prolonged exposure to mist.
Chronic Toxicity: No evidence of sensitization or carcinogenic effects in available studies; chronic, high-dose exposures not well characterized.
Other Data: Mutagenicity and reproductive toxicity have not been thoroughly investigated.
Aquatic Toxicity: No measured data for this specific substance, but research on imidazolium ionic liquids indicates moderate to high acute toxicity to aquatic invertebrates (EC50 for Daphnia typically in tens of mg/L).
Persistence and Degradability: Low volatility limits atmospheric transport; persistency reported due to slow biodegradation rates.
Bioaccumulation: Bioaccumulation potential appears low based on structure; unlikely to accumulate in aquatic organisms.
Mobility in Soil: Water solubility suggests some mobility, but ionic nature tends to keep it out of nonpolar phases; can leach in wet conditions.
Other Adverse Effects: No hazard from ozone depletion or photochemical smog formation documented for this compound.
Disposal Methods: Dispose as hazardous waste according to local, regional, and national regulations; incineration preferred under controlled conditions.
Container Handling: Rinse empty containers cautiously and send to approved waste disposal facility; avoid straight disposal down the drain.
Precautions: Label waste containers accurately with contents and hazards; segregate from incompatible chemicals in waste collection.
Waste Codes: Assign appropriate waste code depending on country/jurisdiction; often falls under organic laboratory chemical waste.
UN Number: Not assigned; not classified as hazardous for ground, air, or marine transport based on most current international standards.
Proper Shipping Name: Non-hazardous chemical sample; always check with latest regulatory guidelines before shipping.
Hazard Class: Not regulated.
Packing Group: Not regulated.
Environmental Hazards: Not regulated as marine pollutant.
Special Precautions: Ensure packagings are leak-proof and secure, include MSDS in shipment, train handlers in safe response to accidental spills.
Labelling Requirements: GHS-compliant label with hazard pictograms and precautionary statements.
Chemical Inventory Status: In some jurisdictions, not listed on major inventories (TSCA, REACH, DSL). Notify regulatory agencies if imported or produced in new regions.
OSHA Status: Not specifically regulated in U.S. OSHA hazardous chemicals list.
US EPA: Not regulated as hazardous waste under RCRA; wastes may still need special handling due to toxicity.
Other Regulations: Ensure compliance with all workplace safety training, SDS accessibility, and chemical hygiene practices as required by national or local labor authorities.
Worker Protection: Rights of workers handling chemicals require clear communication, access to data sheets, and proper PPE.
