Product Name: 1-Ethyl-3-Methylimidazolium Trifluoroacetate
Chemical Formula: C8H11F3N2O2
EC Number: 700-985-1
CAS Number: 143314-17-4
Other Names: EMIM TFA, 1-Ethyl-3-methylimidazolium trifluoroacetate
Recommended Use: Laboratory research, solvent, chemical synthesis
Supplier: Manufacturer or distributor contact information with address and non-emergency phone number
Emergency Phone: Local emergency contact depending on location
Date of Issue: Latest revision date for current information
Classification: Eye irritation, skin irritation, acute toxicity (oral)
GHS Label Elements: Exclamation mark pictogram, signal word: Warning
Hazard Statements: Causes skin and eye irritation; harmful if swallowed
Precautionary Statements: Wear protective gloves and eye protection, wash hands thoroughly after handling, avoid ingestion, seek medical advice on exposure
Potential Health Effects: Prolonged skin contact can cause redness, itching, or dermatitis; ingestion can irritate digestive system; vapor or mist may irritate respiratory tract
Environmental Effects: Possible aquatic toxicity, do not release to waterways
Chemical Identity: 1-Ethyl-3-Methylimidazolium Trifluoroacetate
CAS Number: 143314-17-4
Concentration: 98–100%
Impurities: Trace imidazoles and related compounds (less than 2%)
Molecular Structure: Imidazolium cation with trifluoroacetate anion
Inhalation: Move to fresh air, seek medical attention if symptoms such as coughing, dizziness, or breathing difficulty develop
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water for at least 15 minutes, wash with soap, obtain medical help if irritation persists
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, continue rinsing, immediate medical attention recommended
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, obtain medical attention without delay
Notes to Physician: Treat symptomatically; monitor for delayed effects due to chemical absorption
Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray
Unsuitable Media: Avoid high-pressure water jets as chemical spread can occur
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, hydrogen fluoride, toxic and corrosive vapors
Special Protective Equipment: Self-contained breathing apparatus and full protective gear for firefighters
Special Fire & Explosion Hazards: Liquid may generate irritating or toxic fumes at high temperatures; take precautions for runoff prevention
Personal Precautions: Evacuate unnecessary personnel, ventilate the area, wear appropriate PPE (gloves, goggles, protective clothing)
Environmental Precautions: Prevent entry into drains, soil, or water sources, consider diking for liquid retention
Cleanup Procedures: Absorb spill with inert material (such as sand or diatomaceous earth), collect in suitable container for disposal, decontaminate area with soap and water, ventilate space thoroughly
Emergency Protocols: Report significant releases to agency as required by local regulations
Handling: Keep container tightly closed, handle with care to avoid spills, avoid breathing vapor or contact with skin and eyes, use in well-ventilated locations
Hygiene Practices: Wash hands, forearms, and face thoroughly after handling, remove contaminated clothing and launder before reuse, avoid eating, drinking, or smoking while handling chemical
Storage Conditions: Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers or acids, keep container tightly shut
Incompatibilities: Strong oxidizers, acids, bases, sources of heat or ignition
Packing Materials: Corrosion-resistant, labeled, leakproof containers recommended
Engineering Controls: Chemical fume hood or local exhaust ventilation to limit vapor exposure
Respiratory Protection: Use approved respirator for organic vapors if exposure limits are exceeded or ventilation is inadequate
Eye Protection: Chemical splash goggles or face shield
Skin Protection: Impervious gloves (e.g., nitrile), lab coat or apron, long sleeves and protective shoes
Hygiene Measures: Remove contaminated PPE and wash skin promptly after handling, keep work area clean, do not reuse items that cannot be decontaminated
Appearance: Clear to pale yellow liquid
Odor: Mild, sweet, slightly acidic
pH: Acidic (estimated 4–5 as 10% aqueous solution)
Melting Point: Approximately -5°C to 5°C
Boiling Point: Decomposes above 200°C
Flash Point: >140°C (closed cup—estimate)
Density: 1.27–1.35 g/cm³ at 20°C
Solubility: Miscible with water, polar organic solvents
Viscosity: Moderately viscous, 50–120 mPa·s at 25°C
Vapor Pressure: Low (nearly negligible at room temperature)
Partition Coefficient (log Kow): Estimated below 1
Evaporation Rate: Much slower than water
Chemical Stability: Stable under recommended conditions, sensitive to strong acids, bases, and oxidizing agents
Hazardous Reactions: May react exothermically with concentrated acids and bases, incompatible with strong oxidizers
Decomposition Products: Produces toxic and corrosive fumes, including hydrogen fluoride, trifluoroacetic acid, nitrogen oxides
Polymerization: Does not undergo hazardous polymerization
Other Stability Data: Avoid heat, flames, and direct sunlight
Acute Toxicity: Low to moderate oral and dermal toxicity (LD50 not fully documented but anticipated to exceed 1300 mg/kg in rodents)
Skin Corrosion/Irritation: Causes irritation with repeated or prolonged contact
Eye Damage/Irritation: Causes eye irritation, redness, tearing, possible conjunctivitis
Sensitization: No evidence of skin sensitization in limited testing
Carcinogenicity: No components identified as carcinogens in major databases
Mutagenicity: No data suggesting mutagenic potential
Reproductive Effects: No data indicating reproductive or developmental toxicity
Chronic Effects: Long-term exposure data limited; repeated overexposure might cause organ effects due to imidazolium structure
Ecotoxicity: Moderate hazard to aquatic organisms, estimated LC50 (fish) between 10–100 mg/L
Persistence and Degradability: Not readily biodegradable, may persist in the environment
Bioaccumulative Potential: Low potential for bioaccumulation based on log Kow values
Mobility in Soil: High water solubility, may be mobile under certain conditions
Other Adverse Effects: Data limited on long-term impacts; avoid continuous discharge to the environment
Product Disposal: Incineration recommended in authorized facilities, comply with local and national waste regulations
Contaminated Packaging: Rinse and dispose as controlled waste, recycle containers if possible after thorough cleaning
Special Instructions: Do not discharge to drains, waterways, or soil, consult competent authority before disposal
Waste Code: Consult regulatory guidelines for region-specific codes
UN Number: Not assigned
Transport Hazard Class: Not classified as dangerous for road, sea, or air transport under current international regulations
Packing Group: Not applicable
Special Precautions: Ensure packaging prevents leakage and is well-labeled for contents
Transport Labeling: No special hazard label required; ensure compatibility with other transported substances
MARINE POLLUTANT: Not regulated under IMDG code as marine pollutant
Emergency Transport Information: In the event of spillage follow local emergency protocols and inform authorities as required
TSCA: Listed or subject to significant new use notification
REACH: Registration required for quantities >1 tonne/year within Europe
Other Inventories: May be listed or require notification in regional chemical inventories such as EINECS, DSL, ENCS, AICS
Workplace Regulation: Hazard communication training, safety documentation, exposure monitoring as needed by region
WHMIS / GHS: Classified for irritancy and harmful if swallowed
Other Local Regulations: Review occupational and environmental health guidelines for updates and compliance
