Product Name: 1-Hexyl-3-Methylimidazolium Tosylate
Chemical Formula: C16H24N2O3S
Usage: Laboratory research, solvent applications, chemical synthesis
CAS Number: 424603-50-7
Synonyms: [HMIM][Tosylate], 1-Hexyl-3-methylimidazolium p-toluenesulfonate
Manufacturer: Custom chemical supplier or laboratory distributor details supplied at purchase
Contact Details: Emergency telephone contact provided by supplier, address noted on label
Recommended Restrictions: Not formulated for human or veterinary drug use; not intended for food, cosmetics, or household products
Hazard Classifications: Skin irritant, eye irritant, aquatic toxicity (Acute Category 3, Chronic Category 2 based on component data)
Pictograms: Exclamation mark, aquatic environment
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful to aquatic life with long-lasting effects
Precautionary Statements: Avoid release to the environment. Wear protective gloves/clothing/eye protection/face protection. Wash hands thoroughly after handling
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms: Irritation, redness, tearing, possible allergic response
Chemical Ingredient: 1-Hexyl-3-Methylimidazolium Tosylate
Concentration: ≥98% (purity typical in laboratory-grade bottles)
CAS Number: 424603-50-7
Impurities: Trace imidazole derivatives or alkylating agents, depending on synthesis batch
Inhalation: Move to fresh air. If breathing is labored or irregular, seek immediate medical help. Provide oxygen if available and trained to do so
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for several minutes. Monitor for irritation
Eye Contact: Rinse eyes cautiously under flowing water for at least 15 minutes, holding eyelids apart
Ingestion: Rinse mouth. Never induce vomiting unless directed by medical personnel. Seek medical assistance promptly
Important Symptoms/Effects: Irritation, redness, burning sensation, possible delayed hypersensitivity
Immediate Medical Attention Needed: Serious skin reactions, breathing difficulty, persistent eye pain or vision changes
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam; water spray for larger fires
Unsuitable Extinguishing Media: High-pressure water jets may spread liquid
Specific Hazards: May emit toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides, and sulfur oxides under fire conditions
Protective Equipment for Firefighters: Wear self-contained breathing apparatus (SCBA) and full protective gear
Special Procedures: Cool exposed containers with water mist. Approach fire from upwind
Combustion Products: Incomplete combustion generates hazardous byproducts. Residues may retain hazardous properties
Personal Precautions: Avoid inhalation and contact with skin/eyes. Ventilate area. Remove ignition sources
Spill Response: Absorb with inert material (sand, vermiculite). Place in chemically compatible, clearly labeled container
Environmental Precautions: Prevent run-off into drains, sewers, or waterways
Clean-up Methods: Scoop residues for disposal according to regulations. Wash area with soap and water. Collect and dispose of wash water tested for contamination
Personal Protective Equipment: Chemical-resistant gloves, goggles, lab coat, and respiratory protection if aerosol generation possible
Precautions for Safe Handling: Use local and general exhaust ventilation. Avoid skin and eye contact. Minimize generation of dust, vapor, or mist. Handle inside a chemical fume hood if available
General Hygiene Measures: Remove contaminated clothing before leaving work area. Wash thoroughly after handling. Keep food, beverages, and cigarettes away from handling area
Storage Conditions: Store in a tightly closed container, away from incompatible materials like acids, bases, oxidizers. Keep in a cool, dry, ventilated space, out of direct sunlight
Storage Temperature: Preferably below 30°C; avoid excessive heat
Incompatible Materials: Strong oxidizing agents, strong acids and bases may degrade product or cause hazardous reactions
Control Parameters: No occupational exposure limit set for this compound. General good laboratory practice applies
Engineering Controls: Use fume hood, local exhaust ventilation. Ensure access to eyewash fountains and emergency showers
Personal Protective Equipment: Protective gloves (nitrile or neoprene), splash-proof goggles or face shield, lab coat or chemical apron, closed footwear
Respiratory Protection: Use NIOSH/MSHA approved respirator if dust/vapor is generated or engineering controls not feasible
Environmental Controls: Avoid discharges into the environment. Implement spill containment plans where possible
Appearance: Viscous liquid or soft solid (depending on temperature), colorless to pale yellow
Odor: Slight aromatic—characteristic of tosylate salts
Odor Threshold: Not available
pH: 4–6 (10% solution in water)
Melting Point/Freezing Point: 21–28°C
Boiling Point: Not readily determined (decomposes before boiling)
Flash Point: >180°C (closed cup, estimated based on similar ionic liquids)
Evaporation Rate: Non-volatile
Flammability: Combustible liquid
Upper/Lower Flammability Limits: Not established
Vapor Pressure: Negligible at room temperature
Vapor Density: Not established
Relative Density: 1.08–1.12 g/cm³ (25°C)
Solubility: Miscible with water, soluble in alcohols, DMSO, and many polar organic solvents
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not measured
Decomposition Temperature: Begins above 200°C
Viscosity: High, varies with temperature (may exceed 100 cP at 25°C)
Reactivity: Stable under recommended handling and storage conditions
Chemical Stability: Stable at normal temperatures when kept dry and away from incompatible materials
Possibility of Hazardous Reactions: Contact with strong oxidizers, acids, or bases may result in decomposition and release of hazardous gases
Conditions to Avoid: Elevated temperatures, open flames, prolonged contact with incompatible chemicals
Incompatible Materials: Strong oxidizers, reducing agents, strong acids, strong bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides, imidazole derivatives
Likely Routes of Exposure: Skin and eye contact, ingestion, inhalation (mist or aerosol)
Acute Toxicity: Not fully characterized; low oral and dermal toxicity suggested by analogs
Skin Corrosion/Irritation: May cause moderate, persistent skin irritation
Eye Damage/Irritation: Causes moderate to severe eye irritation, tearing, possible corneal injury on direct splashing
Respiratory Sensitization: Prolonged inhalation of aerosols may irritate nose, throat, and lungs
Germ Cell Mutagenicity: No data available
Carcinogenicity: Not classified, lacks evaluation by IARC, NTP, or OSHA
Reproductive Toxicity: Not established for this substance
Specific Target Organ Toxicity – Single Exposure: No known effects based on available data
Specific Target Organ Toxicity – Repeated Exposure: No long-term studies available
Aspiration Hazard: Unlikely due to viscosity
Ecotoxicity: Harmful to aquatic organisms, especially with prolonged exposures. Ionic liquids may disrupt microbial and aquatic communities
Persistence and Degradability: Limited biodegradation expected; most imidazolium salts resist rapid breakdown
Bioaccumulative Potential: Low to moderate. Few studies track accumulation through food chains
Mobility in Soil: May filter through soil and reach groundwater depending on local conditions
Other Adverse Effects: Discharge into waterways can increase chemical oxygen demand. Product classified as hazardous to aquatic systems under EU regulation
Disposal Procedures: Dispose of contents and container to hazardous or chemical waste collection according to local, regional, and national regulations
Incineration: Use licensed chemical incinerator if available, ensuring emissions control
Contaminated Packaging: Triple rinse containers, render unuseable, dispose as chemical waste
Precautions for Disposal: Do not discharge to sewer, surface water, or soil. Neutralize wastewater after laboratory use to limit environmental release
Regulatory Waste Numbers: Seek classification under local hazardous waste codes (consult regulatory authorities)
UN Number: Not regulated for ground, air, or sea transport under typical laboratory shipping volumes
Proper Shipping Name: Chemical, N.O.S. (contains 1-Hexyl-3-methylimidazolium tosylate)
Transport Hazard Class: Not classified under international or US DOT standards
Packing Group: Not assigned
Hazard Label: Not required
Environmental Hazards: Marked as potentially hazardous to aquatic systems
Special Transport Precautions: Secure tightly capped. Prevent leaks or spills during transit. Emergency procedures in event of accidental release must address product’s irritant and aquatic hazard potential
Inventory Status: May not be listed on TSCA, EINECS, DSL or other national inventories; confirm with authorities before import or commercial use
R&D Exemption: Laboratory and research use may qualify for specific regulatory exemptions with notification and documentation
Hazard Communication: Subject to OSHA Hazard Communication requirements. Ensure SDS and labels provided in all workplaces
Other Regulations: Chemical subject to environmental regulations for industrial discharges. May require reporting under SARA Section 313, Clean Water Act, or local equivalents
Workplace Controls: Implement training and engineering controls under relevant labor safety standards
Labeling Requirements: Clearly indicate product identification, hazard pictograms, precautionary and response phrases per GHS
International Rules: Product may require export notification to certain countries. Check REACH status for use and registration in the EU
Restrictions: Not approved for consumer applications, food, or drug use. Intended for trained professionals with chemical safety experience
