Material Safety Data Sheet: 1-Hydroxyethyl-2,3-Dimethylimidazolium Chloride

Identification

Product Name: 1-Hydroxyethyl-2,3-Dimethylimidazolium Chloride
Chemical Formula: C7H13ClN2O
Synonyms: 2,3-Dimethyl-1-(2-hydroxyethyl)imidazolium chloride
CAS Number: 71450-71-2
Recommended Use: Laboratory research, ionic liquid research, chemical synthesis
Supplier Information: Manufacturer/supplier name, address, phone number provided on packaging
Emergency Contact: National chemical emergency hotline, local first responders' contact

Hazard Identification

GHS Classification: Skin Irritant (Category 2), Eye Irritant (Category 2A), Acute Toxicity Oral (Category 4), Environmental Hazard: Aquatic Chronic (Category 3)
GHS Label Elements: Exclamation mark, Environmental hazard pictogram
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; can be harmful if swallowed; may cause long-term adverse effects in the aquatic environment
Precautionary Statements: Avoid contact with skin and eyes; do not ingest; wear appropriate protective gear; prevent release to the environment
Potential Health Effects: Skin and mucous membrane irritation, possible respiratory symptoms upon prolonged exposure, gastrointestinal upset if ingested

Composition / Information on Ingredients

Chemical Name: 1-Hydroxyethyl-2,3-Dimethylimidazolium Chloride
Concentration: ≥98% (as supplied)
Impurities: Trace water, unreacted precursors (<0.1%)
Hazardous Components: Entire compound under REACH, CLP classifications; no additional high-risk ingredients
Molecular Weight: 176.65 g/mol

First Aid Measures

Inhalation: Remove to fresh air, support breathing if needed, seek medical attention for persistent symptoms
Skin Contact: Rinse thoroughly with soap and plenty of water for 10-15 minutes, remove contaminated clothing, seek medical help for irritation or burns
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if easy, continue rinsing, obtain medical advice if pain or redness persists
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, contact a physician immediately
Notes to Physician: Treat symptomatically, monitor for allergic or systemic reactions

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Specific Hazards: May emit hazardous fumes (HCl, nitrogen oxides, carbon oxides) upon combustion
Protective Equipment: Self-contained breathing apparatus, fully protective clothing recommended for fire-fighting personnel
Precautions: Use water spray to cool containers, move containers away from fire zone if safe, avoid inhaling combustion gases
Explosion Hazard: No specific explosion risk, but thermal decomposition may produce toxic gases

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, lab coat; ventilate area; restrict access to spill area
Environmental Precautions: Avoid release to drains, soil, water bodies; notify authorities if large quantities enter environment
Spill Cleanup Methods: Absorb with inert material (sand, vermiculite), collect residues in suitable container, wash area with soapy water, dispose according to local guidelines
Decontamination: Ventilate and wash spill site after material pickup is complete

Handling and Storage

Handling: Use in a well-ventilated area, avoid inhalation and contact with skin, avoid repeated or prolonged exposure, do not eat, drink, or smoke while handling
Storage: Store in a tightly closed container, keep in a cool, dry, well-ventilated place, keep away from heat, sources of ignition, strong oxidizers and acids, segregate from food and beverages
Specific Storage Requirements: Use secondary containment, label container clearly, restrict access to trained personnel

Exposure Controls and Personal Protection

Engineering Controls: Operate in fume hood or use local exhaust, ensure eyewash stations and safety showers nearby
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), protective lab coat, safety goggles, suitable respiratory protection for powders or vapors above exposure limits
Hygiene Measures: Wash hands after handling, change contaminated clothing, avoid touching face, maintain proper lab practices
Exposure Limits: No occupational exposure limits established, minimize exposure as best practice

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Mild, characteristic
pH (1% solution): Approx. 6.0-7.5
Melting Point: 117-125°C
Boiling Point: Decomposes on heating, no boiling point at normal conditions
Solubility: Soluble in water, slightly soluble in ethanol
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.15 g/cm³
Partition Coefficient (Log Kow): Not available
Other Properties: Hygroscopic, may absorb moisture from air
Flash Point: Not flammable under normal use

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No spontaneous hazardous reactions under ambient conditions
Conditions to Avoid: High temperatures, moisture, direct sunlight, contact with strong acids or oxidizers
Incompatible Materials: Strong acids, oxidizing agents, anhydrides
Hazardous Decomposition Products: Hydrogen chloride gas, nitrogen oxides, carbon oxides may form on thermal decomposition
Polymerization: Will not occur under standard handling

Toxicological Information

Acute Toxicity: Estimated LD50 (oral, rat): >500 mg/kg (harmful if swallowed in large quantities)
Skin Corrosion/Irritation: May cause local skin irritation, redness, discomfort
Serious Eye Damage/Eye Irritation: Eye contact can lead to irritation, watering, redness, possible corneal damage with high exposure
Respiratory Sensitization: No data on sensitization, dust may irritate airways
Germ Cell Mutagenicity: No data available
Carcinogenicity: No recognized risk based on available information
Reproductive Toxicity: Insufficient data for classification
Repeated Dose Toxicity: Prolonged overexposure may affect skin, eyes, and digestive system
Target Organs: Eyes, skin, gastrointestinal tract

Ecological Information

Aquatic Toxicity: May be toxic to aquatic organisms, risk of long-term adverse effects in aquatic environments
Persistence and Degradability: No detailed degradation data; ionic liquids may persist in the environment
Bioaccumulation: Low potential, given hydrophilic nature, but lack of study data warrants caution
Mobility in Soil: Likely mobile in aqueous environments, potential for seepage into groundwater
Other Adverse Effects: Uncontrolled release to environment not advised, limits for effluent release recommended

Disposal Considerations

Waste Disposal Methods: Dispose of as hazardous waste at authorized facility, follow national/local regulations for chemical disposal
Container Disposal: Triple rinse and render unusable, follow official procedures for chemical packaging waste
Special Precautions: Do not flush down drains, do not mix with incompatible waste streams, keep clear of food and water sources during disposal

Transport Information

UN Number: Not classified as dangerous goods for transport by most carriers
Transport Hazard Class: Non-regulated
Packing Group: Not applicable
Environmental Hazards: Prohibited discharge to natural surface water during transport
Special Precautions: Ensure packaging integrity, secure containers against breakage, label correctly, alert carriers to chemical nature
ADR/RID, IMDG, IATA: Not listed, follow local and international rules as best practice

Regulatory Information

TSCA Status: Not listed in publicly available TSCA Inventory
REACH Status: Registration may be required if manufactured/imported above 1 ton/year in EU
WHMIS Classification: D2B (Toxic, Irritant)
OSHA HazCom: Irritant; training and SDS must be provided to users
Other National/International Regulations: Check specific country obligations, local workplace safety requirements, specific concentration limits for discharge or handling, notification requirements for storage above threshold quantities