Product Name: 1-Hydroxyethyl-3-Methylimidazolium Hexafluorophosphate
Chemical Formula: C6H11F6N2OP
Synonyms: [HEMIm][PF6], 1-(2-Hydroxyethyl)-3-methylimidazolium hexafluorophosphate
CAS Number: 133038-12-5
Recommended Uses: Solvent, catalyst in synthesis, ionic liquids study
Supplier Details: Contact information, mailing address, and emergency telephone
Emergency Information: International CHEMTREC number, local poison control contacts
Hazard Classification: Acute toxicity (oral), corrosive to metals, eye damage/irritation, aquatic acute and chronic hazards
Signal Word: Danger
Pictograms: Skull and crossbones, corrosive, exclamation mark, environment
Hazard Statements: May cause burns to eyes and skin, possible harmful if swallowed or inhaled, can damage mucous membranes, severe eye irritation, may damage aquatic life with long-lasting impacts
Precautionary Statements: Avoid breathing vapors or contact with skin and eyes, ensure proper ventilation, wear chemical-resistant gloves and splash-proof goggles, avoid release to environment
Chemical Name: 1-Hydroxyethyl-3-Methylimidazolium Hexafluorophosphate
CAS Number: 133038-12-5
Concentration: ≥99%
Impurities: May contain trace levels of imidazole derivatives, organic or inorganic byproducts under 1%
Other Identifiers: No other significant components
Inhalation: Remove to fresh air immediately, keep the person at rest, seek medical attention without delay if symptoms persist
Skin Contact: Wash thoroughly with soap and running water for at least 15 minutes, remove contaminated clothing, consult a medical professional for lingering irritation or burns
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get immediate medical advice if discomfort does not ease
Ingestion: Rinse mouth, do not induce vomiting, drink water in small sips if alert, call poison control or seek medical aid as quickly as possible
Notes for Doctor: Treat for exposure to corrosive chemicals and monitor for respiratory and gastrointestinal distress
Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or alcohol-resistant foam
Unsuitable Media: Avoid water jets which may spread the chemical
Specific Hazards: During combustion, produces toxic and corrosive gases including hydrogen fluoride, phosphorus oxides, nitrogen oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full chemical protective gear
Special Firefighting Mehods: Keep containers cool with water spray to limit pressure build-up, evacuate area, prevent runoff from entering waterways
Personal Precautions: Wear protective gloves, chemical splash goggles, and laboratory apron, prevent inhalation and skin exposure, ventilate the area well
Environmental Precautions: Avoid release to waterways, drains, and soil, notify authorities if a large spill contaminates the environment
Containment and Cleaning: Isolate the area, absorb spill with inert materials like sand or vermiculite, collect in sealed containers, dispose in line with hazardous waste protocols, decontaminate surfaces with soap and water
Handling: Use only in fume hoods or well-ventilated areas, avoid direct contact with skin, eyes, and clothing, do not eat, drink, or smoke near the product, keep containers tightly closed after use, employ dedicated equipment for transfer and measurement
Storage: Store in corrosion-resistant, sealed containers away from moisture, heat, strong acids and bases, and incompatible materials such as oxidizers, label containers clearly, restrict access to authorized personnel, temperature-controlled storage recommended between 2°C and 8°C to minimize decomposition and pressure build-up
Occupational Exposure Limits: No established regulatory limits, minimize exposure as much as practical
Engineering Controls: Local exhaust ventilation or fume hoods critical for safe handling, spill containment measures, eyewash stations, and safety showers should be available
PPE: Chemical-resistant gloves, splash-proof safety goggles, lab coats or aprons, use a NIOSH-approved respirator when airborne exposure risks exist, remove contaminated clothing immediately
Hygiene Measures: Wash hands thoroughly after handling; keep food, beverages, and smoking materials out of the handling area; dispose of gloves and other disposable protective gear after each use
Appearance: Transparent to pale yellow liquid at room temperature
Odor: Faint, characteristic
Melting Point: Approximately -20°C to -15°C
Boiling Point: Decomposes before boiling
Flash Point: >150°C (closed cup)
Solubility: Partially soluble in water, highly soluble in polar organic solvents
Vapor Pressure: Negligible at ambient conditions
Density: 1.34–1.39 g/cm3 at 20°C
pH: Acidic, typically below 3 (aqueous)
Viscosity: Moderate (exact value varies with temperature)
Partition Coefficient (n-octanol/water): Not measured, expected low
Auto-Ignition Temperature: Not available
Evaporation Rate: Very slow
Chemical Stability: Stable under recommended storage conditions, sensitive to strong moisture, light, and heat
Possible Reactions: Decomposes in the presence of moisture, gives hazardous hydrogen fluoride and imidazole derivatives
Incompatible Materials: Water, strong bases, strong oxidizing agents, alkalis, acids, silicates, halogenated compounds
Hazardous Decomposition Products: Hydrogen fluoride, phosphorous oxides, fluorinated organic compounds, nitrogen oxides
Polymerization: Not known to undergo hazardous polymerization
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Possible moderate toxicity by oral and dermal routes, may cause severe irritation or burns
Chronic Effects: Prolonged exposure can damage respiratory and gastrointestinal tracts, no confirmed evidence of carcinogenicity, mutagenicity, or reproductive toxicity, data limited
Symptoms: Redness, pain, severe irritation, possible chemical burns, respiratory trouble if inhaled, nausea and vomiting after ingestion
Sensitization: Not reported
Target Organs: Eyes, skin, mucous membranes, respiratory system
LD50/LC50 Data: No manufacturer-supplied figures available
Acute Aquatic Toxicity: Harmful to fish, invertebrates, and algae, may persist in aquatic environments
Chronic Aquatic Toxicity: Effects include bioaccumulation in aquatic life and long-term aquatic toxicity
Mobility: Moderate solubility in water, potential for leaching in soil and migration to surface waters
Persistence and Degradability: Suspected to resist rapid degradation, can accumulate in aquatic and terrestrial environments
Bioaccumulation: Potential for accumulation in aquatic organisms is unknown, fluorinated compounds tend toward persistence
Other Adverse Effects: Spills may cause toxic effects in soil and water ecosystem, restrict releases to environment at all stages of use and disposal
Waste Handling: Collect liquid and contaminated materials in specified hazardous chemical waste containers, label clearly, avoid mixing with regular waste streams
Disposal Methods: Arrange for destruction through accredited chemical waste contractors, thermal destruction in hazardous waste incinerators preferred under conditions reducing acid gases
Container Disposal: Triple rinse empty containers with compatible solvent, dispose as hazardous waste, do not reuse
Environmental Precautions: Prevent spills and residues from entering water bodies or sewers, follow local, regional, and national hazardous waste laws strictly
UN Number: Consult applicable international transport agencies for the assigned UN code
Proper Shipping Name: Corrosive liquid, organic, N.O.S. (1-Hydroxyethyl-3-Methylimidazolium Hexafluorophosphate)
Transport Hazard Class: 8—Corrosive substances
Packing Group: II
Environmental Hazards: Marine pollutant
Special Precautions: Mark corrosive, keep upright, prevent container breakage or leaks, transport only in suitable packages, provide hazard communication to carriers
Global Inventories: May not appear on all chemical inventory lists (TSCA, REACH, DSL, ENCS, AICS, IECSC), users should check compliance for country of use
Labeling: Meets GHS hazard labeling—including pictograms, signal word, H and P statements
OSHA Regulation: Considered hazardous as defined in OSHA Hazard Communication Standard
SARA Title III: Not listed as an extremely hazardous substance, but all releases above reporting threshold require notification
REACH, CLP, and Other Regional Standards: Requires compliance with classification, packaging, and labeling requirements, always consult applicable jurisdictional laws
Worker Safety: Ensure training in safe handling, PPE, emergency response, and spill containment
Other Regulations: Observe any restrictions or special requirements for import, export, manufacture, or downstream use specified by local agencies
