Product Name: 1-Hydroxyethyl-3-Methylimidazolium Tosylate
Chemical Family: Ionic Liquid
Chemical Formula: C13H18N2O3S
Synonyms: [HEMIM][OTs], EMI Tosylate
CAS Number: 615506-42-8
Intended Use: Laboratory use, solvent, catalyst carrier
Supplier Contact: Emergency phone and address of manufacturer or distributor supplied on packaging label
Classification: Irritant to skin and eyes based on imidazolium derivatives, can cause respiratory discomfort through dust or mist, not classified as carcinogenic, not known to be mutagenic
Label Elements: GHS07 (Exclamation mark), Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory tract irritation, may cause drowsiness or dizziness if inhaled
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing dust or mist, wash hands thoroughly after handling, use only outdoors or in well-ventilated areas
Other Hazards: May cause environmental harm if released; toxic to aquatic life
Chemical Composition: Mixture (substance)
Main Ingredient: 1-Hydroxyethyl-3-Methylimidazolium Tosylate (approximately 99%)
Impurities: Minor by-products from synthesis (unreacted imidazole <0.1%)
Additives: None declared
General Advice: Move person to fresh air, seek medical attention if symptoms persist
Inhalation: Remove to fresh air; if breathing fails, perform artificial respiration, consult physician
Skin Contact: Wash area with soap and water, remove contaminated clothing, seek medical advice for irritation or burns
Eye Contact: Rinse immediately with plenty of water for 15 minutes, remove contact lenses if present, visit eye specialist
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical personnel, consult physician if symptoms appear
Symptoms and Effects: Burning, redness, itching, coughing, nausea
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, carbon dioxide, dry chemical powder
Unsuitable Media: Do not use water jet on large fires; can spread burning liquid
Special Hazards: Releases toxic or corrosive gases on combustion (SOx, NOx, CO, imidazole fumes)
Protective Equipment: Wear full protective suit, self-contained breathing apparatus, keep upwind of fire
Firefighting Instructions: Cool closed containers with water, ventilate area
Personal Precautions: Use gloves, eye protection, face shield, approved respirator for dusts/mists
Environmental Precautions: Prevent entry into drains, surface or groundwater; alert authorities in significant spill
Cleanup Methods: Absorb with inert material like vermiculite or sand, collect in containers for proper disposal, ventilate spill area, wash surface with plenty of water
Methods for Containment: Cover drains, use diking to prevent spread
Handling: Avoid contact with skin, eyes, and clothing, handle under well-ventilated conditions, avoid generating aerosol, do not eat or drink while working
Storage: Keep in tightly closed containers, store in cool, dry, well-ventilated area away from strong acids, bases, oxidizers, incompatible materials
Storage Temperature: Room temperature, avoid temperatures above 40°C
Incompatible Materials: Strong oxidizers (peroxides, permanganates), acids, bases, moisture-sensitive chemicals
Control Parameters: No workplace exposure limits set for this product, monitor dust/mist levels
Engineering Controls: Local exhaust ventilation, fume hood, ensure eyewash stations are accessible
Respiratory Protection: Use NIOSH-approved respirator if aerosol forms
Hand Protection: Chemical-resistant gloves (nitrile, neoprene), remove contaminated gloves and wash hands thoroughly
Eye/Face Protection: Chemical safety goggles, face shield
Skin/Body Protection: Lab coat or chemical apron, avoid open-toe shoes
Appearance: Yellow to pale amber viscous liquid or crystalline solid
Odor: Faint aromatic, slightly sulfurous
pH: 4–6 (measured as 20% solution in water)
Melting Point: 40–55°C
Boiling Point: Decomposes above 220°C
Flash Point: >100°C (closed cup)
Evaporation Rate: Negligible under ambient conditions
Solubility: Readily soluble in water, methanol, ethanol, DMSO
Specific Gravity: 1.2–1.3
Vapor Pressure: Low at ambient temperature
Viscosity: High viscosity at room temperature
Partition Coefficient (log Kow): Not established
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Strong heat, sunlight, moisture, sources of ignition
Incompatible Materials: Strong oxidizers, acids, bases; may react violently
Decomposition Products: CO, CO2, SOx, NOx, imidazole derivatives
Polymerization: Does not polymerize
Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: May cause mild to moderate irritation to skin, respiratory tract, mucous membranes
Chronic Toxicity: Limited evidence on long-term effects; structurally related compounds suggest possible liver and kidney stress with repeated, high exposure
Sensitization: No strong evidence for allergic sensitization
Carcinogenicity: Not listed by IARC, OSHA, NTP as carcinogenic
Mutagenicity: Not expected to be mutagenic based on available data
Reproductive Effects: No information on reproductive toxicity
Symptoms of Overexposure: Burning, stinging in eyes and throat, dry or cracked skin, nausea, dizziness
Ecotoxicity: Harmful to aquatic organisms, avoid direct release into environment
Biodegradability: Limited data, ionic liquids often show slow biodegradation
Bioaccumulation: Not expected to bioaccumulate significantly
Mobility: Soluble in water, may partition into groundwater if spilled
Other Adverse Effects: May disrupt aquatic ecosystem function if large amounts reach waterways
Waste Treatment Methods: Collect product and contaminated material in suitable containers, dispose through licensed chemical waste disposal contractors
Disposal of Product: Do not dump into drains or environment, incinerate under controlled conditions
Disposal of Packaging: Empty containers must be triple rinsed before recycling or disposal according to local regulations
Special Precautions: Follow local, national, and international rules for hazardous waste
UN Number: Not regulated as a hazardous material under USDOT, IMDG, IATA regulations
Proper Shipping Name: Chemical, not otherwise specified
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazard: Not classified as marine pollutant
Transport Precautions: Keep containers tightly sealed, prevent leaks and spills during transport
OSHA: Not specifically regulated
TSCA: Listed or subject to review for listing
REACH Information: Registration may be required for imports into the EU above 1 tonne per year
Other International Rules: Not on major restricted or banned lists
Labeling: Follows Globally Harmonized System (GHS) for hazard communication
Workplace Restrictions: General duty to minimize exposure, use best practice risk management
