Chemical Name: 1-Propylimidazole
Synonyms: N-Propylimidazole, 1-Propyl-1H-imidazole
CAS Number: 1679-49-2
Recommended Use: Laboratory reagent, intermediate for chemical synthesis
Manufacturer: Details available on supplier’s label
Contact Details (Product Information): Emergency telephone number and address listed by supplier
GHS Classification: Flammable Liquids (Category 3), Acute Toxicity – Oral (Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2A)
Pictograms: Flame, Exclamation mark
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation; may be harmful if swallowed; flammable liquid and vapor
Precautionary Statements: Keep away from heat, sparks, open flames; avoid breathing fumes; wear protective gloves and eye protection; wash thoroughly after handling
Chemical Identity: 1-Propylimidazole
Concentration: Typically >99%
Molecular Formula: C6H10N2
Molar Mass: 110.16 g/mol
Impurities: Trace amounts of related imidazoles or solvents (if any)
Inhalation: Move person to fresh air. Encourage deep breathing. Seek medical attention if symptoms persist such as headache, dizziness, or respiratory distress.
Skin Contact: Remove contaminated clothing. Wash affected skin with soap and plenty of water. Seek medical aid if skin irritation develops.
Eye Contact: Rinse eyes with running water for several minutes, lifting eyelids to clear from all surfaces. Remove contact lenses if easy. Seek doctor’s care for persistent discomfort.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Get medical advice if you feel unwell.
Most Important Symptoms and Effects: Irritation of eyes, skin, or respiratory tract; nausea or headache possible after swallowing or inhaling
Suitable Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical, or water spray
Specific Hazards: May emit toxic fumes of nitrogen oxides or carbon oxides in fire
Special Equipment: Full protective gear and self-contained breathing apparatus required for firefighters
Advice for Firefighters: Cool containers exposed to flames with water mist to prevent rupture. Prevent run-off from entering drains or waterways.
Personal Precautions: Evacuate area. Wear gloves, eye protection, and, if required, a respirator.
Environmental Precautions: Keep away from drains, soil, and waterways. Contain spill as much as possible.
Methods for Clean-Up: Absorb with inert material such as sand or vermiculite. Collect residue for disposal in tightly closed container. Ventilate affected area after clean-up.
Handling: Avoid inhalation, ingestion, or any direct contact with skin and eyes. Use only in well-ventilated areas. Keep away from incompatible materials like oxidizers.
Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place. Segregate from strong acids, bases, and oxidizing agents. Keep away from direct sunlight and ignition sources. Label containers clearly.
Engineering Controls: Use fume hood or local exhaust ventilation to minimize airborne exposure. Provide safety showers and eye wash stations near work area.
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat, suitable face protection
Respiratory Protection: Use appropriate respirator if airborne concentrations reach exposure limits or if ventilation is not adequate
Hygiene Measures: Do not eat, drink, or smoke during use. Wash hands thoroughly after handling. Remove contaminated clothing immediately and clean before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Characteristic, amine-like
Melting Point: Not available or below room temperature
Boiling Point: Around 205°C (401°F)
Density: Approximately 1.01 g/cm³ at 25°C
Solubility: Miscible with water and most organic solvents
Vapor Pressure: Low at room temperature
Flash Point: 94°C (201°F) closed cup
Autoignition Temperature: Not readily available
pH: Alkaline in water solution
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Reacts with strong oxidizing agents
Hazardous Decomposition: Possible emission of nitrogen or carbon oxides if burned
Incompatible Materials: Avoid contact with acid chlorides, anhydrides, strong acids, and oxidizers
Polymerization: Hazardous polymerization unlikely under normal conditions
Acute Toxicity: Moderately toxic if swallowed (estimated oral LD50 in rats: 375-600 mg/kg)
Skin Corrosion/Irritation: Potential to cause local irritation with redness or rash on contact
Serious Eye Damage/Irritation: Can cause severe discomfort, redness, or watering
Inhalation Route: Vapors can trigger coughing, shortness of breath, possible dizziness if levels are high
Chronic Effects: No reliable evidence suggesting carcinogenicity, teratogenicity, or mutagenicity
Sensitization: Not known to cause allergic reaction on the skin
Target Organs: Respiratory system, gastrointestinal tract, skin, and eyes
Ecotoxicity: Harmful to aquatic life at high concentrations; toxicity data for fish or daphnia limited
Persistence/Degradability: Likely biodegradable with time, but breakdown rate varies depending on conditions
Bioaccumulative Potential: Low potential expected due to moderate solubility and rapid degradation in environment
Mobility in Soil: May migrate in soil with water due to solubility
Other Adverse Effects: Avoid uncontrolled release to the environment
Waste Handling: Dispose of in accordance with national and local regulations
Methods of Disposal: Send to licensed waste handler for chemical incineration or treatment
Contaminated Packaging: Rinse containers and treat as chemical waste
Precautions: Prevent chemical from entering drains or water sources. Label waste containers clearly.
UN Number: 2810
Proper Shipping Name: Toxic, liquid, organic, n.o.s. (contains 1-Propylimidazole)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Not listed as marine pollutant
Special Transport Precautions: Seal containers securely. Protect from physical damage and heat during transport. Comply fully with regulations for road, rail, air, or sea shipment.
Labeling Requirements: Follows OSHA Hazard Communication Standard (29 CFR 1910.1200), GHS-compliant labeling required
TSCA Status: Listed
EINECS Number: 216-850-8
Other Registration: REACH registration as required by importer/supplier
Restrictions: Use subject to local, state, federal, and international regulation. Workers must review workplace safety plans prior to handling.
SARA Title III/Sec 313: Not classified as a reportable quantity chemical
California Proposition 65: Not listed as carcinogenic or as reproductive toxin
