Product Name: 2-Bromophenol
Synonyms: ortho-Bromophenol, o-Bromophenol
Chemical Formula: C6H5BrO
CAS Number: 95-56-7
EC Number: 202-427-5
Relevant Identified Uses: Laboratory chemicals, chemical synthesis
Supplier Information: Chemical distributor and laboratory supplier contact details remain on file
Emergency Contact Number: Available through supplier or regional poison control centers
GHS Classification: Acute Toxicity, Skin Irritant, Eye Irritant, Hazardous to Aquatic Life
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled, causes skin irritation, causes serious eye irritation, toxic to aquatic organisms
Pictograms: Exclamation mark, Environment
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, avoid release to the environment, wear protective gloves and eye/face protection
Chemical: 2-Bromophenol
Purity: ≥98%
Concentration: 100% (single ingredient)
Impurities: Low-level impurities found in technical or laboratory-grade supplies, not considered to present significant additional hazards at trace amounts
Inhalation: Move exposed person to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms continue
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical advice for prolonged irritation
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, lift eyelids occasionally, seek medical help promptly
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek immediate medical attention
Most Important Symptoms/Effects: May cause sore throat, coughing, redness or irritation of skin and eyes, abdominal pain if ingested
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Avoid full water jet directly on burning product
Specific Hazards: Produces toxic fumes of bromine and hydrogen bromide under fire conditions
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing
Special Precautions: Keep containers cool with water spray, avoid water runoff entering drains
Personal Precautions: Evacuate unnecessary personnel, ventilate area, use suitable protective equipment
Environmental Precautions: Prevent entry to sewers and waterways, inform responsible authorities if significant spill reaches environment
Methods for Cleanup: Collect with inert absorbent material (sand, clay), scoop into labeled waste containers, wash area with plenty of water after material pickup
Precautions for Safe Handling: Avoid direct contact with skin, eyes, and clothing, avoid inhalation of vapors and dust, use within fume hood or well-ventilated area, do not eat, drink, or smoke while handling this chemical
Conditions for Safe Storage: Store in tightly closed original container, keep in cool, dry, and well-ventilated place away from heat, strong oxidizers, acids, and bases, protect from moisture, keep separately from food and feedstuffs
Control Parameters: No occupational exposure limit values established specifically for 2-Bromophenol
Engineering Controls: Work under local exhaust ventilation or in a chemical fume hood
Individual Protection: Chemical splash goggles, chemical-resistant gloves (nitrile or butyl rubber recommended), protective laboratory coat, respiratory protection if dust or vapor forms
Environmental Controls: Avoid release into environment, secure proper waste management infrastructure
Appearance: Colorless to pale yellow crystalline solid
Odor: Distinct phenolic odor
Odor Threshold: Not available
pH: Not applicable (solid)
Melting Point: 62 - 65°C
Boiling Point: 221 - 223°C
Flash Point: >110°C (closed cup)
Evaporation Rate: Not available
Flammability: May form combustible dust concentrations in air
Vapor Pressure: <0.01 mmHg (20°C)
Vapor Density: >1 (air = 1)
Relative Density: 1.73 g/cm³
Solubility: Slightly soluble in water, soluble in organic solvents (such as ethanol, ether)
Partition Coefficient (log Pow): Estimated at 2.7
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not available
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong oxidizing agents, bases, acids
Hazardous Reactions: Can liberate toxic and corrosive fumes (hydrogen bromide, bromine) on decomposition
Conditions to Avoid: Excess heat, open flames, moisture
Incompatible Materials: Strong oxidizers, alkali metals, strong bases, acid anhydrides
Hazardous Decomposition Products: Bromine vapors, hydrogen bromide, carbon oxides
Acute Toxicity: Harmful if ingested, inhaled, or in contact with skin
LD50 (Oral, Rat): Estimated between 500–2000 mg/kg
Skin Corrosion/Irritation: Produces skin irritation on prolonged or repeated contact
Eye Damage/Irritation: Causes significant eye irritation
Respiratory or Skin Sensitization: Not classified as a sensitizer, although prolonged exposure may result in allergic-type reactions in some individuals
Germ Cell Mutagenicity: No data to suggest mutagenic effects
Carcinogenicity: No classification as a carcinogen by IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: Limited studies available, not classified in this category
Specific Target Organ Toxicity (Single Exposure): May cause respiratory irritation if inhaled
Specific Target Organ Toxicity (Repeated Exposure): Not classified
Other Effects: Prolonged or repeated exposure may result in effects on central nervous system, liver, and kidneys as seen with related phenolic compounds
Ecotoxicity: Highly toxic to aquatic organisms (LC50 values for fish and daphnia range from 1 to 10 mg/L)
Persistence and Degradability: May not be readily biodegradable; persists in soil and water
Bioaccumulative Potential: Potential for bioaccumulation due to moderate partition coefficient
Mobility in Soil: Tends to adsorb to soil particles, but some mobility can occur depending on soil composition and moisture
Other Adverse Effects: Environmental monitoring recommended in case of major spill, avoid unnecessary release to environment
Waste Treatment Methods: Dispose of product and contaminated packaging as hazardous waste, follow local, regional, and national regulations governing waste disposal
Small Quantities: Place in sealed, clearly labeled chemical waste containers for collection by licensed disposal contractor
Large Quantities: Coordinate with environmental health and safety authorities for bulk disposal, do not allow to enter drains or watercourses
Contaminated Packaging: Containers should be thoroughly emptied, rinsed if possible, and disposed of according to hazardous waste procedures
UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains 2-Bromophenol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions for Users: Handle with full protective equipment, transport only in well-sealed and correctly labeled containers
Transport in Bulk According to Annex II of MARPOL: Not applicable for product as supplied
Safety, Health, and Environmental Regulations: Subject to chemical safety and control laws in most jurisdictions; refer to OSHA, TSCA (USA), REACH (EU), WHMIS (Canada), or other regional frameworks
Inventory Status: Listed on major inventories (TSCA, EINECS/ELINCS, DSL/NDSL)
Hazard Symbols (according to regulation): Harmful; Dangerous for the environment
Risk Phrase(s): R22: Harmful if swallowed; R36/38: Irritating to eyes and skin; R51/53: Toxic to aquatic organisms, may cause long-term adverse effects
SARA Title III (Section 313): Not specifically listed
California Proposition 65: Not listed as a hazardous chemical
Other Regulatory Information: Always check the most recent local legislation for controls and compliance requirements, update safety practices with emerging data
