MSDS: 2-Hydroxy-N,N,N-Trimethylethanaminium Acetate

Identification

Product Name: 2-Hydroxy-N,N,N-Trimethylethanaminium Acetate
Synonyms: Choline Acetate
CAS Number: 820-96-2
Manufacturer: Consult packaging or supplier documentation for current details
Recommended Uses: Used in chemical synthesis, laboratory research, and as a nutrient component
Emergency Telephone: Refer to local regulations and product label for contact number
Address: Manufacturer information present on shipment documentation

Hazard Identification

GHS Classification: Not classified as hazardous under GHS for most regions
Signal Word: None required under GHS
Hazard Statements: Not expected to pose an acute hazard
Precautionary Statements: Avoid contact with eyes, skin, and clothing, avoid inhalation of dust
Hazards Not Otherwise Classified: Dust may cause mild irritation to respiratory tract, may be an irritant in large quantities
NFPA Ratings: Health: 1, Flammability: 1, Reactivity: 0

Composition / Information on Ingredients

Chemical Identity: 2-Hydroxy-N,N,N-Trimethylethanaminium Acetate
Common Name: Choline Acetate
CAS Number: 820-96-2
Concentration: 98-100% by weight
Impurities: Residual water and trace organic contaminants possible from production

First Aid Measures

Inhalation: Move individual to fresh air, seek medical attention if symptoms develop
Skin Contact: Wash with plenty of water and mild soap, remove contaminated clothing and wash before reuse
Eye Contact: Rinse with gentle stream of water for several minutes, lift eyelids to flush thoroughly, seek medical advice if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical help if feeling unwell
Symptoms: May include irritation, redness, coughing or discomfort depending on exposure route

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, or foam
Specific Hazards: May emit toxic fumes of nitrogen oxides and acetic acid under extreme heat
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective gear
Special Procedures: Cool exposed containers with water spray, avoid inhalation of smoke or fumes
Combustion Products: Carbon oxides, nitrogen oxides, acetic acid vapors

Accidental Release Measures

Personal Precautions: Wear appropriate personal protective equipment including gloves, safety goggles, and dust mask
Environmental Precautions: Prevent material from entering drains or waterways
Methods for Cleanup: Sweep or vacuum up the spilled material, collect in a closed, labeled container for disposal, wash spill site with water after material pickup
Respiratory Protection: Required in areas with dust generation or poor ventilation
Decontamination: Wash exposed surfaces thoroughly after cleanup

Handling and Storage

Precautions for Safe Handling: Avoid creating dust, avoid skin or eye contact, use only with adequate ventilation
Storage Conditions: Store in a tightly closed container in a cool, dry, well-ventilated place, keep away from strong acids and oxidizers
Incompatible Materials: Strong oxidizing agents, strong acids
Other Recommendations: Keep storage areas free from food and drink, label containers clearly with substance name and hazard information

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established exposure limits from ACGIH, OSHA, or NIOSH
Engineering Controls: Use local exhaust ventilation to keep dust levels below nuisance thresholds
Personal Protective Equipment: Safety goggles, gloves, standard laboratory coat
Respiratory Protection: Use dust mask or respirator if ventilation is insufficient or dust levels are high
Hygiene Measures: Wash hands before breaks and after use, avoid touching face during handling

Physical and Chemical Properties

Appearance: White to off-white powder or crystalline solid
Odor: Mild, faintly amine-like
pH: Approximately 4.5 to 6.0 (1% solution)
Melting Point / Range: 170 – 180°C
Boiling Point: Decomposes before boiling
Flash Point: Not established
Solubility: Freely soluble in water
Vapor Pressure: Negligible at room temperature
Specific Gravity: 1.1-1.2 (water = 1)
Partition Coefficient (Log Pow): Not available
Viscosity: Not relevant for solid
Decomposition Temperature: Above 180°C
Evaporation Rate: Not applicable as a solid

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Incompatible Substances: Avoid strong oxidizers, strong acids, and bases
Hazardous Reactions: No dangerous reactions expected if used as designated
Decomposition Products: Generates nitrogen oxides, carbon monoxide, carbon dioxide, and acetic acid under fire or thermal decomposition
Conditions to Avoid: Excessive heat, contact with incompatible materials, generation of dust

Toxicological Information

Acute Toxicity: Low acute toxicity in animal and cell line studies
Skin Contact: Low to mild irritant, not considered sensitizing
Eye Contact: Mild irritation possible
Inhalation: Dust inhalation may cause coughing or mild respiratory discomfort
Ingestion: Low toxicity, large quantities may cause gastric upset or discomfort
Chronic Effects: No evidence of long-term toxicity in humans
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: No known mutagenic risk identified
Reproductive Toxicity: No adverse developmental or reproductive effects reported in relevant literature

Ecological Information

Aquatic Toxicity: No acute toxicity expected to aquatic organisms in typical concentrations
Persistence and Degradability: Compound expected to be readily biodegradable in natural systems
Bioaccumulation Potential: Low potential for bioaccumulation based on structure and water solubility
Mobility in Soil: Likely high mobility due to high water solubility
Other Adverse Effects: No evidence of environmental hazard from routine laboratory or industrial use

Disposal Considerations

Waste Disposal Methods: Dispose of as non-hazardous chemical waste in accordance with national, regional, and local regulations
Contaminated Packaging: Empty containers should be triply rinsed and disposed of as solid waste
Special Precautions: Do not discharge into drains, surface water, or soil directly
Recommended Treatment: Controlled incineration or landfill in designated facilities

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Not classified as a hazardous material
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: None known, not classified as marine pollutant
Special Transport Precautions: Keep containers tightly closed, avoid spills during transit, protect from moisture

Regulatory Information

Labelling: Product can be shipped under general goods transport codes
OSHA Status: Not regarded as hazardous under OSHA regulations
TSCA Status: Listed or exempted
REACH Status: Listed or exempted
SARA/Title III Categories: Not reportable
California Proposition 65: Not subject to listing
Other Information: Complies with major chemical inventory requirements in the US, Canada, EU, Japan, and Australia