Product Name: 2-Hydroxy-N,N,N-Trimethylethanaminium Hydrogen Sulfate
Synonyms: Choline sulfate, Trimethylethanolammonium hydrogen sulfate
Recommended Uses: Laboratory reagents, chemical synthesis, nutraceutical and pharmaceutical component
Manufacturer Information: Name, address, emergency contact number, business telephone number
CAS Number: 6211-24-1
EC Number: 228-213-8
Relevant Identified Uses: Only for research and industrial applications, not for food or household purposes
Global Harmonized System classification: Eye irritation Category 2A, Skin irritation Category 2
Signal Word: Warning
Hazard Statement: Causes skin irritation, causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves and eye protection, avoid contact with skin and eyes, seek medical attention after exposure
Other Hazards: Not classified as hazardous by inhalation or environmental exposure under most protocols, do not ingest.
Chemical Name: 2-Hydroxy-N,N,N-Trimethylethanaminium Hydrogen Sulfate
Concentration: 100% (commercial grade, no significant impurities affecting classification)
Molecular Formula: C5H15NO4S
Molecular Weight: 185.24 g/mol
Inhalation: Move person to fresh air, keep comfortable for breathing, consult a doctor if feeling unwell, provide artificial respiration if needed
Skin Contact: Remove contaminated clothing, wash affected skin thoroughly with soap and water, seek medical attention if irritation persists
Eye Contact: Rinse eye(s) with water for several minutes, remove contact lenses if possible, continue rinsing, get medical advice immediately
Ingestion: Rinse mouth with water, do not induce vomiting, give water if fully conscious, get immediate medical assistance
Suitable Extinguishing Media: Powder, foam, carbon dioxide, water spray
Specific Hazards: Thermal decomposition can produce toxic vapors including nitrogen oxides, sulfur oxides
Protective Equipment for Firefighters: Wear full protective gear and self-contained breathing apparatus
Explosion Hazards: Not considered an explosion hazard under normal conditions, avoid dust formation
Personal Precautions: Use protective clothing, chemical-resistant gloves, and goggles; ensure adequate ventilation
Spill Clean-Up Methods: Sweep up and collect, avoid creating dust, place in closed container for disposal
Environmental Precautions: Prevent spill from entering drains, surface water, or groundwater
Decontamination: Wash spill site after material pick-up is complete, dispose cleaning materials as hazardous waste
Handling: Use within a chemical fume hood or ventilated area, avoid breathing dust and direct contact with skin and eyes, practice good hygiene
Storage: Store in tightly closed container, keep in a cool, dry, and well-ventilated space away from strong oxidizers and acids, label storage area clearly
Specific End Use Safety Instructions: Restrict access to trained personnel, use control measures to avoid accidental release or exposure
Occupational Exposure Limits: No established regulatory threshold, handle with general safe-work precautions
Engineering Controls: Use local exhaust ventilation, safety shower and eye-wash station in the immediate work area
Personal Protective Equipment: Safety goggles, lab coat, chemical-resistant gloves, suitable respirator if dust becomes airborne
General Hygiene Practices: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse, no eating or drinking in handling areas
Appearance: White to off-white solid or crystalline powder
Odor: Mild, characteristic
Odor Threshold: Not available
pH: 3–4 (5% solution in water)
Melting Point: Decomposes above 210 °C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible
Relative Density: 1.25–1.30 g/cm³
Solubility: Freely soluble in water, slightly soluble in ethanol
Partition coefficient (n-octanol/water): Not determined
Auto-ignition temperature: Not self-igniting
Decomposition Temperature: Above 210 °C
Viscosity: Not relevant for solids
Chemical Stability: Stable under recommended storage conditions
Possible Hazardous Reactions: Reacts with strong oxidizing and reducing agents, acids and bases
Conditions to Avoid: Moisture, prolonged high temperatures, contamination
Incompatible Materials: Strong oxidizers, metallic powders, strong bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, methylamine compounds can form in case of thermal decomposition
Acute Toxicity: Oral, dermal, and inhalation data suggest low toxicity; LD50 (oral, rat): not available; LD50 (dermal, rat): not available
Skin Corrosion/Irritation: Causes moderate to strong skin irritation on direct contact
Serious Eye Damage/Irritation: Causes strong eye irritation; risk of damage increases with prolonged exposure
Respiratory Sensitization: Dust or powder particles can irritate airways; no data on sensitization
Repeated Exposure: Prolonged or frequent contact may cause dermatitis
Ingestion: Ingestion may cause digestive tract discomfort, nausea, or vomiting
Carcinogenicity/Mutagenicity/Reproductive Toxicity: No evidence or data indicating carcinogenic, mutagenic, or reproductive toxicity effects, not listed by IARC, NTP, ACGIH, or OSHA
Aquatic Toxicity: No reliable data on specific aquatic toxicity, likely to be biodegradable over time
Persistence and Degradability: Structure suggests slow degradation in the environment; follows natural nitrogen and sulfur cycles
Bioaccumulative Potential: Low, compound is water-soluble and distributes readily
Mobility in Soil: High mobility due to high solubility in water; potential for leaching into groundwater
Other Adverse Effects: Large spills may affect aquatic environments through eutrophication; always avoid uncontrolled discharge to surface water
Waste Disposal: Dispose of as hazardous chemical waste in accordance with local, regional, and national regulations, store in clearly labeled containers
Contaminated Packaging: Empty containers should be rinsed thoroughly, offered for recycling if appropriate, or managed as hazardous waste
Disposal Methods: Do not pour into drains, surface water, or soil; use professional waste disposal services for safe treatment and disposal
UN Number: Not regulated for transport by road, sea, or air under most international protocols
Proper Shipping Name: Not dangerous goods
Transport Hazard Class: Not classified as hazardous
Packing Group: None assigned
Environmental Hazards: Not regulated as marine pollutant
Special Precautions: Prevent packaging damage, secure loads in transit to avoid accidental release
TSCA Status: Listed or compliant in the United States
EINECS/ELINCS Number: 228-213-8
REACH Status: Registered or pre-registered under EU regulation
OSHA Hazard: Eye and skin irritant
SARA Title III: Not subject to reporting under Sections 302, 304, 313
Other Regulations: Meets domestic and international safety chemical management standards, follow specific directives in each country of operation
Labeling Requirements: Ensure packaging and labeling meet GHS and regional regulatory standards, include hazard pictograms, signal words, and statement codes
