Product Name: 3-Bromopropionic acid
Synonyms: β-Bromopropionic acid, 3-Bromopropanoic acid
CAS Number: 598-72-1
Recommended Use: Laboratory chemicals, industrial applications
Supplier Details: Chemical distributors, laboratory supply firms
Emergency Contact: Local poison center, 911 in case of major exposure
Classification: Corrosive to metals, Acute toxicity (oral, dermal, inhalation), Skin corrosion/irritation, Eye damage/irritation
Signal Word: Danger
Hazard Statements: Harmful if swallowed, Causes severe skin burns and eye damage, Harmful if inhaled
Pictograms: GHS05 (corrosive), GHS07 (exclamation mark)
Precautionary Statements: Wear protective gloves/heavy clothing; avoid inhalation; wash hands after handling
Chemical Name: 3-Bromopropionic acid
Purity: ≥97%
Molecular Formula: C3H5BrO2
Molecular Weight: 153.98 g/mol
Impurities: Lower brominated acids or related halogenated compounds possible at trace levels
Inhalation: Remove affected person to fresh air, keep at rest, seek medical attention for cough, difficulty breathing, or irritation.
Skin Contact: Remove contaminated clothing immediately, rinse skin with plenty of water for 15 minutes, consult medical professional.
Eye Contact: Rinse thoroughly with water for at least 15 minutes, lifting upper and lower eyelids, call ophthalmologist.
Ingestion: Do not induce vomiting, rinse mouth, drink water if conscious, seek emergency medical care at once.
Notes for Physician: Treat symptomatically; monitor for respiratory distress or chemical burns.
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Media: Direct water stream may spread corrosive liquid
Fire Hazards: Thermal decomposition produces corrosive and toxic fumes including hydrogen bromide, carbon oxides
Firefighter Protection: Wear self-contained breathing apparatus, full chemical protective suit
Special Precautions: Use water spray to cool unopened containers; avoid inhaling vapors
Personal Precautions: Evacuate area, ventilate, avoid skin and eye contact
Spill Clean Up: Absorb with inert material such as sand or earth, place in closed container for disposal
Environmental Precautions: Prevent entry into drains, sewers, or watercourses
Protective Equipment: Nitrile gloves, protective goggles, laboratory coat, certified chemical respirator if vapors present
Disposal: Dispose waste according to local regulations, label clean-up containers clearly
Handling: Use only in a well-ventilated workspace, avoid inhaling dust or vapor, avoid splashing or contact
Hygiene Measures: Wash hands after manipulation, do not eat or drink near the substance
Storage Conditions: Keep container tightly closed, store in cool, dry place away from direct sunlight and incompatible substances
Incompatibles: Strong bases, oxidizing reagents, reducing agents, alkali metals
Storage Temperature: 2–8°C recommended
Exposure Limits: No specific Occupational Exposure Limits, use local guidelines for corrosive substances
Engineering Controls: Chemical fume hood, local exhaust ventilation
Personal Protective Equipment (PPE): Chemical splash-resistant goggles, face shield, nitrile gloves, laboratory apron, vapor respirator for large-scale or prolonged exposure
Environmental Controls: Use containment to avoid contamination of environment, filter or scrub air exhausts when possible
Appearance: Colorless to pale yellow liquid or crystalline solid
Odor: Slight, pungent
Odor Threshold: Not readily determined
Melting Point: 44–46°C
Boiling Point: 192°C at 760 mmHg
Flash Point: 110°C (closed cup)
Solubility: Miscible with water, soluble in alcohols and ethers
Vapor Pressure: 0.2 mmHg at 20°C
pH: Acidic, value <1 for concentrated solutions
Density: 1.75 g/cm³ at 25°C
Viscosity: Not established
Partition Coefficient (log P): 0.43
Chemical Stability: Stable under standard temperature and storage conditions
Reactivity: Reacts with aqueous bases and strong oxidizers, may hydrolyze slowly in moist air
Hazardous Decomposition: Produces hydrogen bromide, carbon monoxide, carbon dioxide on combustion or decomposition
Incompatible Materials: Alkali metals, moisture, oxidizing agents
Polymerization: Not expected under normal conditions
Routes of Exposure: Inhalation, skin, eye, ingestion
Acute Oral Toxicity: LD50 (rat) 170 mg/kg, moderate hazard
Skin Corrosion/Irritation: Severe skin irritation and possible burns
Eye Damage/Irritation: Risk of severe or permanent eye injury
Inhalation Toxicity: Cough, burning sensations, chest pain; high concentrations pose respiratory risk
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Other Effects: May cause gastrointestinal tract damage if swallowed, persistent coughing when inhaled, pronounced eye pain; no evidence of chronic toxicity with low-dose, brief exposures
Aquatic Toxicity: Harmful to aquatic organisms, short-term exposure poses risk to fish and invertebrates
Persistence and Degradability: Expected to hydrolyze slowly, some biodegradation in the environment
Bioaccumulative Potential: Low, log P value suggests limited bioaccumulation
Mobility in Soil: May leach to groundwater due to water solubility, persistent in high concentrations
Other Adverse Effects: Acidification of water bodies possible, highly toxic to microorganisms at elevated levels
Disposal Method: Dispose through licensed hazardous waste contractor or incineration with flue gas scrubbers
Contaminated Packaging: Triple rinse containers, dispose as chemical waste
Precautions: Avoid release to the environment, comply with local and federal hazardous waste disposal requirements
Recommended Containers: High-density polyethylene or glass bottles, securely sealed and labeled
Do Not: Pour down drain, landfill, or dispose with regular garbage
UN Number: UN 3265
Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (3-Bromopropionic acid)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Labeling: Corrosive (Class 8), marine pollutant where applicable
Environmental Hazards: Marine pollutant, hazardous to aquatic life in case of spill
Special Transport Precautions: Package upright, use secondary containment, segregate from bases, oxidizers
US TSCA Status: Listed or exempted
SARA Section 313: Not subject to reporting requirements
OSHA HazCom: Corrosive hazard, acute toxicity
EU REACH Status: Registration may be required for certain uses
GHS Classification: Skin corrosion/irritation; acute toxicity
Other International Lists: May be regulated in countries outside the US and EU under chemical safety laws
Label Requirements: Hazard pictograms, signal word “Danger”, hazard statements on every primary and secondary container
