Product Name: 3-Bromopropyltriphenylphosphonium bromide
Synonyms: Triphenylphosphonium, 3-bromopropyl, bromide
CAS Number: 53297-98-2
Recommended Use: Laboratory chemical, research, synthesis
Supplier: Chemical supply, research labs
Emergency Contact Number: Refer to regional Poison Control Center and emergency fire department
GHS Classification: Eye Irritation, Skin Irritation, Acute Toxicity (Oral and Inhalation), Specific Target Organ Toxicity - Single Exposure
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Pictograms: Exclamation Mark
Precautionary Statements: Do not breathe dust/fume/gas/mist/vapors; wash exposed skin thoroughly; wear protective gloves and eye protection; avoid food, drink, and smoking near the chemical
Potential Health Effects: May cause burning sensation, abdominal pain, headache, dizziness, or coughing; allergy or sensitivity may arise with repeated use
Chemical Name: 3-Bromopropyltriphenylphosphonium bromide
Chemical Formula: C21H20Br2P
Molecular Weight: 480.17 g/mol
Impurities: None indicated in reagent grade material; specialty grades may show traces of water or residual solvents
Concentration: Over 95% active substance in standard packaging
General Advice: Move victim to fresh air; prevent further contact; remove contaminated clothing
Skin Contact: Wash skin thoroughly with soap and water; seek medical help if irritation develops or persists
Eye Contact: Rinse cautiously with plenty of water for at least 15 minutes, holding eyelids open; consult ophthalmologist if discomfort or redness continues
Inhalation: Take victim outside; support breathing; call physician for continued respiratory distress or coughing
Ingestion: Rinse mouth; do not induce vomiting; seek immediate medical attention and provide MSDS to responders
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray (avoid direct contact with water jet)
Unsuitable Extinguishing Methods: Do not use full water jet, splashing may spread contamination
Hazardous Combustion Products: May form toxic and irritating fumes of phosphorus oxides, carbon oxides, hydrogen bromide
Special Protective Equipment: Wear full fire-fighting gear, self-contained breathing apparatus, chemical-resistant clothing
Special Firefighting Procedures: Move containers from fire zone; cool unopened drums with water mist; take care to avoid breathing in smoke or fumes
Personal Precautions: Wear suitable personal protective equipment; keep people not involved in the cleanup out of the area
Environmental Precautions: Prevent further leakage, spillage, or entry into water courses and soil
Containment Methods: Absorb spilled product with inert material (vermiculite, dry sand)
Cleanup Procedures: Sweep up, shovel into secure containers for disposal; ventilate area; wash spill zone after pickup with soap solution
Special Considerations: Avoid raising dust; do not allow material to spread uncontrolled; follow local regulations
Handling Precautions: Work in well-ventilated spaces, avoid raising or inhaling dust, wear appropriate PPE; always wash hands after use
Hygiene Measures: No eating, drinking, or smoking in the work area; remove contaminated clothes and wash before reuse
Storage Conditions: Store product in a dry, well-ventilated location away from heat, light, ignition sources; close containers tightly
Storage Temperature: Keep at 2–8°C if possible
Incompatibilities: Strong oxidizers, moisture, acids, alkalis
Exposure Limit Values: No specific exposure limits set by OSHA or ACGIH for this material
Engineering Controls: Use chemical fume hood, exhaust fans, and eye wash stations close to work
Personal Protective Equipment: Gloves resistant to chemicals, lab coats, safety goggles with splash protection, NIOSH-approved respirator if dust exposure possible
Hygiene Measures: Regular handwashing after handling; decontaminate tools and surfaces
Environmental Controls: Avoid discharging into drains or the environment; use local containment
Appearance: White to off-white crystalline solid
Odor: Odorless or faint aromatic
pH: Not applicable (solid material)
Melting Point/Range: 227–231°C
Boiling Point/Range: Decomposes before boiling
Flash Point: Not flammable under standard conditions
Solubility: Soluble in water, methanol, DMSO
Vapor Pressure: Not available
Relative Density: Not determined
Partition Coefficient (log Kow): Not determined
Autoignition Temperature: Not available
Odor Threshold: Not known
Stability: Stable under recommended storage and handling conditions; sensitive to moisture and acids
Reactivity: May react with oxidizers, strong acids, alkalis
Hazardous Decomposition: Phosphine compounds, bromine, carbon monoxide, carbon dioxide on combustion
Polymerization: No hazardous polymerization expected
Conditions to Avoid: Excessive heat, prolonged exposure to air and light, humidity
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through the skin; LD50 values not fully defined in literature
Skin Irritation: Causes localized redness, dryness, may result in burns with prolonged contact
Eye Irritation: Direct contact causes pain, redness, tearing
Respiratory Effects: Dust or fumes irritate mucous membranes, coughing, difficulty breathing in sensitive individuals
Chronic Effects: Prolonged or repeated exposure can worsen respiratory and allergic symptoms, no current evidence of carcinogenicity or mutagenicity specific to this compound
Aquatic Toxicity: Avoid release to water systems, may be hazardous to aquatic organisms
Persistence and Degradability: No comprehensive studies available; structure suggests slow breakdown
Bioaccumulation Potential: No data; structurally may persist in sediment
Mobility in Soil: Low volatility, likely limited mobility due to ionic nature
Other Adverse Effects: Brominated byproducts may impact local ecosystems near disposal sites
Waste Disposal: Treat as hazardous waste; follow chemical disposal protocols for laboratory material; absorb with inert materials and seal in approved containers
Contaminated Packaging: Rinse containers, dispose of as hazardous waste according to regional authorities
Sewage Disposal: Avoid introduction to drains, sewers, or water bodies
Special Instructions: Consult local, national, or regional regulations before disposal; incineration in licensed facility suggested for bulky amounts
UN Number: Not classified as a dangerous good by DOT, IATA, or IMDG
Proper Shipping Name: Chemical substance, not otherwise specified
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Special Precautions: Avoid breakage or exposure to heat, moisture during transport; keep sealed and labeled
Environmental Hazards: Not considered hazardous for transportation in limited quantities, but large spills qualify for notification
TSCA Status: Not listed or subject to significant new use rule at time of literature search
SARA 313: Not listed as a toxic chemical under SARA Title III Section 313
California Proposition 65: Not listed for carcinogenicity, reproductive, or developmental hazards
EU Regulation: Not registered under REACH as of last available review
Other International Standards: Check regional regulatory obligations for importing, using, and disposing; compliance may vary
