MSDS for 3-Carboxypropyltriphenylphosphonium Bromide

1. Identification

Product Name: 3-Carboxypropyltriphenylphosphonium Bromide
Chemical Formula: C22H22BrO2P
Synonyms: Triphenylphosphonium, 3-carboxypropyl-, bromide
Recommended Use: Laboratory chemical, research and development
Manufacturer Details: Supplier name, full address, emergency phone line, regular contact line
Emergency Overview: White to off-white crystalline powder, slight odor, non-volatile under ambient conditions

2. Hazard Identification

GHS Classification: Eye Irritant (Category 2A), Skin Irritant (Category 2), Specific Target Organ Toxicity (Category 3, single exposure)
Label Elements: Signal Word: Warning, Hazard pictograms: Exclamation mark
Hazard Statements: Causes skin and eye irritation, may be harmful if swallowed, respiratory tract irritation possible
Precautionary Statements: Avoid contact with skin, eyes, and clothing, use only with adequate ventilation, wash hands thoroughly after handling

3. Composition / Information on Ingredients

Chemical Name: 3-Carboxypropyltriphenylphosphonium Bromide
CAS Number: 208486-03-7
EC Number: Not assigned
Concentration: More than 98% by weight
Impurities: Trace (<1%) possible, individual impurities unspecified

4. First Aid Measures

Inhalation: Move person to fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Remove affected clothing, rinse skin with water for at least 15 minutes, seek care for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if worn, continue rinsing, seek medical evaluation
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek attention for persistent discomfort
Acute Symptoms: Redness or irritation of skin or eyes, sore throat, coughing, possible gastrointestinal upset

5. Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Specific Hazards: Toxic fumes of carbon oxides, phosphorus oxides, and hydrogen bromide possible under fire conditions
Protective Equipment: Firefighters must wear full protective gear and self-contained breathing apparatus
Explosion Hazard: No known risk of explosion under normal use, substance not identified as flammable or explosive

6. Accidental Release Measures

Personal Precautions: Use personal protective equipment including gloves, goggles, lab coat, avoid breathing dust
Environmental Precautions: Prevent entry into drains, soil, and natural waters
Cleanup Methods: Sweep up and collect in suitable container for disposal, ventilate area, wash spill site after material pickup
Containment: Use absorbent materials if necessary, avoid creating airborne dust

7. Handling and Storage

Handling: Avoid inhalation and contact with skin, eyes, and clothing, use in a chemical fume hood or well-ventilated space, avoid generating dust
Storage: Store in original container tightly closed in a cool, dry, well-ventilated area, protect from light and incompatible substances, prevent unauthorized access, keep away from strong oxidizing agents

8. Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood, local exhaust ventilation
Threshold Limit Value: No occupational exposure limits established
PPE for Eyes: Chemical goggles or face shield
PPE for Skin: Resistant gloves, laboratory coat, sleeves
PPE for Respiratory: Dust mask or respirator if ventilation is inadequate or during clean-up
General Controls: Wash hands thoroughly before breaks and after handling

9. Physical and Chemical Properties

Appearance: White to off-white powder or crystalline solid
Odor: Odorless or faint characteristic odor
pH (1% solution): Not established
Melting Point: Range generally around 275 to 280°C (decomposition possible before melting)
Boiling Point: Not applicable, decomposes
Solubility: Soluble in water and common organic solvents
Density: Approximately 1.4-1.6 g/cm³
Vapor Pressure: Negligible
Partition Coefficient: Not established
Flammability: Not considered flammable
Auto-ignition Temperature: Not available
Explosive Properties: Not classified as explosive
Viscosity: Not applicable in solid form

10. Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Not expected to be reactive under normal circumstances
Hazardous Reactions: Reacts with strong oxidizing agents
Conditions to Avoid: Heat, moisture, open flame, exposure to light
Materials to Avoid: Strong acids and oxidizing agents
Hazardous Decomposition Products: Bromide vapors, phosphorus oxides, carbon oxides

11. Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Oral LD50 not established, may cause irritation to digestive tract
Chronic Exposure: Data limited, repeated exposure could cause skin or respiratory sensitization
Skin Corrosion/Irritation: Causes moderate irritation in animal test systems
Serious Eye Damage/Irritation: Moderate eye irritation possible
Respiratory Sensitization: No data
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Mutagenicity: No data available
Developmental/Reproductive Toxicity: No relevant data found

12. Ecological Information

Ecotoxicity: Data not available, avoid uncontrolled release to environment
Persistence and Degradability: Not expected to degrade readily in the environment
Bioaccumulation: Bioaccumulation potential not known
Mobility in Soil: Likely to remain localized due to low volatility
Other Adverse Effects: Unknown, proper containment and disposal advised

13. Disposal Considerations

Waste Disposal Method: Dispose through licensed chemical waste contractor, incineration preferred
Regulations: Follow local, regional, national, and international regulations
Contaminated Packaging: Dispose of container as chemical waste after triple rinsing
Precautions: Do not flush to sewer, release to natural waters, or landfill untreated

14. Transport Information

UN Number: Not assigned
Proper Shipping Name: Not regulated under ADR, RID, DOT, IATA as a dangerous good
Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: Not listed as marine pollutant
Special Precautions for Transport: Keep tightly sealed, avoid moisture and physical damage during transit

15. Regulatory Information

Labelling: GHS compliant labeling required
TSCA Status: Not listed
REACH Status: Exempt or not registered, research use only
Other Regulations: No restrictions established under OSHA, SARA Title III, or CERCLA for laboratory use
Safety, Health, and Environmental Regulations/Legislation Specific for the Substance: Use PPE as indicated, handle as hazardous laboratory chemical