Product Name: 8-Bromooctanoyl Chloride
Synonyms: Octanoyl chloride, 8-bromo-; 8-Bromooctanoyl chloride; 8-Bromooctanoic acid chloride
Molecular Formula: C8H14BrClO
Molecular Weight: 241.56 g/mol
CAS Number: 89374-58-7
Recommended Use: Laboratory reagents, synthetic intermediate for organic chemistry
Manufacturer: Not specified here for generic application.
Contact Information: Provided on shipment paperwork and product label.
GHS Classification: Skin Corrosion/Irritation (Category 1B), Serious Eye Damage (Category 1), Acute Toxicity Oral & Dermal (Category 4), Acute Toxicity Inhalation (Category 3)
Pictograms: Corrosive, Skull and Crossbones
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage; harmful if swallowed; toxic by inhalation; causes respiratory irritation
Precautionary Statements: Avoid breathing vapor or mist; use only outdoors or in well-ventilated area; wear protective gloves/clothing, eye/face protection; wash exposed skin thoroughly after handling; seek medical advice if you feel unwell; store locked up.
Chemical Name: 8-Bromooctanoyl Chloride
Content: ≥98% by weight
Impurities: Trace brominated octanoic acid derivatives and hydrochloric acid, potential solvent residues below 1% each
CAS Number: 89374-58-7
REACH Registration: Not available for research chemicals.
Other Identifiers: No additional hazardous additives present under standard formulations.
Inhalation: Remove person to fresh air immediately; monitor breathing; provide artificial respiration or oxygen as indicated; call poison center or doctor
Skin Contact: Remove contaminated clothing right away; flush skin with copious amounts of water for at least 15 minutes; do not delay; seek immediate medical attention
Eye Contact: Rinse thoroughly with water for at least 15 minutes, lifting upper and lower eyelids; remove contact lenses if possible; get urgent medical help
Ingestion: Rinse mouth, do not induce vomiting; give water only if conscious; seek medical care without delay
Notes for Doctors: Treat as corrosive agent; support respiration; watch for delayed pulmonary edema or tissue injury.
Suitable Extinguishing Agents: Dry chemical, carbon dioxide, foam; do not use water directly on substance
Hazards Arising from Combustion: Liberates toxic gases including hydrogen bromide, hydrochloric acid, phosgene, carbon monoxide and carbon dioxide upon burning
Specific Hazards: Reacts with water releasing corrosive vapors and heat
Protective Equipment for Firefighters: Self-contained breathing apparatus and chemical protective clothing; keep exposed containers cool by spraying with water—avoid contact with substance
Firefighting Instructions: Approach fire from upwind position; avoid inhalation of vapors and combustion products.
Personal Precautions: Evacuate area; wear positive-pressure respirator, chemical-resistant gloves, full body suit
Environmental Precautions: Prevent release into waterways, sewers, and soil
Containment: Absorb spill with earth, sand or inert absorbent; collect in sealed chemical waste container
Cleanup Methods: Ventilate area after cleanup; neutralize residues with dilute sodium bicarbonate or similar basic material, then flush with water—collect runoff for disposal as hazardous waste
Decontamination: Do not allow contaminated absorbents to dry out; move containers to well-ventilated, secure area; label for proper disposal.
Safe Handling: Keep container tightly closed; avoid all contact with skin, eyes, and clothing; use only inside fume hood; never open containers in humid environment
Storage Requirements: Store in tightly sealed original container, in cool, dry, well-ventilated location; segregate from strong bases, water sources, alcohols, amines, and oxidizing or reducing agents
Incompatibilities: Avoid contact with moisture, acids, and reactive metals
Other Precautions: Keep locked up and out of reach of unauthorized personnel; minimize quantities stored on site; use secondary containment.
Engineering Controls: Require use of ventilated enclosure or chemical fume hood; supply eyewash stations and emergency showers in work area; monitor air levels with appropriate gas detection
Personal Protective Equipment (PPE): Chemical splash goggles, face shields, rubber gloves, lab coat or apron; chemical-resistant footwear
Respiratory Protection: Wear NIOSH-approved full-face respirator with acid gas/organic vapor cartridges for non-routine tasks
Hygiene Measures: No eating, drinking, smoking, or cosmetics in work area; wash hands and exposed skin after work; launder contaminated clothing before reuse
Exposure Limits: No established occupational exposure limits for this compound; handle under assumption of high acute toxicity.
Physical State: Oily, colorless or pale yellow liquid
Odor: Pungent, irritating
Melting Point: Data not available; expected below room temperature
Boiling Point: Decomposes before boiling; expected around 237–242°C at atmospheric pressure, but hydrolyzes readily
Density: Estimated 1.25–1.35 g/cm³ at 25°C
Solubility: Decomposes violently in water; soluble in organic solvents such as dichloromethane
Vapor Pressure: Low at room temperature
Flash Point: Data not available; assumed non-flammable under typical use
pH: Not applicable (hydrolyzes in water)
Reactivity: Reacts with water and moist air to release fumes of HCl and HBr.
Chemical Stability: Stability retained under sealed, dry, inert atmosphere away from sunlight
Incompatible Materials: Water, alcohols, amines, bases, acid chlorides, reducing/oxidizing agents, strong acids and bases, moist air, metals
Hazardous Decomposition Products: Hydrogen bromide, hydrochloric acid, carbon oxides
Polymerization: No known risk of hazardous polymerization
Conditions to Avoid: Exposure to moisture, elevated temperatures, sunlight, open flames; avoid mechanical shock during handling.
Acute Toxicity: Harmful by ingestion, skin contact, inhalation; LD50 (rat, oral): Not established, but expected to be in the moderate range based on related compounds
Irritation/Corrosivity: Causes severe burns to eyes, skin, and mucous membranes; symptoms may include redness, swelling, pain, permanent tissue damage
Sensitization: No data for this compound, treat as possible sensitizer
Chronic Effects: No long-term data; repeated or prolonged exposure may cause dermatitis, respiratory impairment
Other Health Hazards: Inhalation of vapors or mists may cause delayed lung edema and systemic effects; ingestion can cause burns to mouth, throat, and stomach, risk of perforation
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Specific testing not found; structurally related alkyl halides linked to mutagenicity in vitro, but no direct evidence for this compound.
Ecotoxicity: Highly toxic to aquatic life and invertebrates due to reactivity and potential to hydrolyze to HCl and HBr; may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Degrades rapidly in presence of water; breaks down to organic acids and halide ions; breakdown products may lower pH and harm organisms
Bioaccumulation: Significant bioaccumulative potential unexpected due to hydrolysis, but bromo-organic byproducts may persist
Mobility in Soil: Rapidly reacts with moisture in soil, forming immobile residues and hydrochloric/bromic acids
Other Adverse Effects: Release into environment should be prevented; avoid discharge to surface water, sewer, or soil.
Waste Handling: Must not be disposed of with regular waste or down the drain; must be neutralized and treated as hazardous waste
Recommended Disposal Method: Incinerate in licensed facility following complete neutralization; ensure destruction of halogenated volatiles
Contaminated Packaging: Decontaminate by triple rinsing with compatible solvent, neutralize rinsate, dispose of packaging as hazardous waste
Regulatory Disposal Code: Check local, regional, and national hazardous waste regulations for classification.
Special Precautions: Notify authorities in case of large or environmental releases.
UN Number: 3265
Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (8-Bromooctanoyl Chloride)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Marine Pollutant: Yes
Special Precautions: Avoid temperature extremes, secure upright; keep away from incompatible cargo; clearly label as corrosive and marine pollutant per shipping rules
DOT (US): Hazardous Material, subject to all related regulations.
IATA and IMDG: Subject to restrictions; check with carrier or forwarding agent for special requirements.
OSHA Status: Classified as hazardous chemical according to OSHA Hazard Communication Standard (29 CFR 1910.1200)
TSCA: Listed or subject to reporting under Toxic Substances Control Act
REACH: Not pre-registered; limited to research and development use
SARA: Not listed under SARA Title III sections 302, 304, or 313
California Proposition 65: Not on the list, but handle as possible carcinogen or reproductive toxin
Other International Regulations: Subject to chemical control laws in EU, Japan, Canada, Australia—consult local and national regulations
Label Requirements: GHS-compliant labeling indicating corrosive and toxic hazards, supplier details, and precautionary measures.
