Product Name: Cetylpyridinium Bromide
CAS Number: 24602-77-9
Synonyms: 1-hexadecylpyridinium bromide, CPB
Recommended Use: Antimicrobial agent in oral care, disinfectant
Supplier Information: Commercial chemical distributors, laboratory suppliers
Emergency Phone Contact: Listed on supplier's product label
Classification: Acute Toxicity, Category 4 (oral, dermal), Skin Corrosion/Irritation, Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed or in contact with skin. Causes skin irritation. Causes serious eye damage.
Precautionary Statements: Avoid breathing dust. Wash hands after handling. Wear protective gloves, protective clothing, eye protection, and face protection.
Pictograms: Exclamation mark, Corrosive symbol
Health Hazards: Irritation, burns on contact, harmful systemic effects after ingestion or inhalation
Substance: Cetylpyridinium Bromide
Chemical Formula: C21H38BrN
Concentration: ≥98% (pure)
Other Components: No significant impurities expected
Skin Contact: Rinse immediately with water for several minutes. Remove any contaminated clothing. Seek medical attention for burns or persistent irritation.
Eye Contact: Rinse eyes cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Get medical attention.
Inhalation: Move to fresh air. Support breathing if necessary. Seek medical attention if symptoms persist.
Ingestion: Rinse mouth. Do not induce vomiting unless directed by medical personnel. Get medical help if feeling unwell.
Notes for Physicians: Treat symptoms, maintain fluid and electrolyte balance, monitor respiratory and cardiac function.
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or alcohol-resistant foam.
Specific Hazards: May emit toxic fumes of bromine, nitrogen oxides, carbon oxides on decomposition.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing.
Special Procedures: Prevent runoff from fire control from entering drains or waterways.
Personal Precautions: Wear gloves, protective clothing, and goggles. Provide proper ventilation. Avoid dust formation.
Environmental Precautions: Prevent product from getting into drains, waterways, soil.
Containment Methods: Sweep up and shovel material into suitable container for disposal. Avoid generating dust.
Cleaning Methods: Clean area thoroughly after material pickup. Wash contaminated area with water.
Handling: Avoid contact with eyes, skin, and clothing. Avoid inhaling dust. Use recommended personal protective equipment. Work in ventilated areas.
Storage Conditions: Store in tightly closed container. Keep in cool, well-ventilated, dry area. Protect from light.
Incompatible Materials: Strong oxidizing agents, acids and bases.
Hygiene Measures: Wash hands before breaks, after handling, before eating or drinking.
Exposure Limits: No occupational exposure limits set by OSHA, ACGIH, NIOSH.
Engineering Controls: Use local exhaust ventilation or chemical fume hood.
Personal Protection: Safety glasses or goggles, gloves resistant to chemicals, laboratory coat or apron.
Respiratory Protection: Use approved dust/mist respirator if ventilation is inadequate.
Skin Protection: Suitable gloves (nitrile, neoprene).
Eye/Face Protection: Safety goggles or face shield.
Hygiene Practices: Remove contaminated clothing, wash hands after use, avoid eating or drinking in work area.
Appearance: White, crystalline powder
Odor: Slight, characteristic smell
pH: 6.0–7.5 (1% solution in water)
Melting Point: 238–243°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Solubility: Freely soluble in water, ethanol
Relative Density: 1.1–1.2 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): ~3.6 (estimated)
Chemical Stability: Stable under normal temperatures and pressures.
Reactivity: Reacts with strong oxidizing agents, acids, and bases producing hazardous byproducts.
Decomposition Products: Bromine compounds, nitrogen oxides, carbon monoxide, carbon dioxide.
Conditions to Avoid: Extreme heat, open flames, exposure to direct sunlight, moisture.
Acute Toxicity: Oral LD50 (rat): 36 mg/kg. Inhalation LC50 and Dermal LD50 not established.
Skin Corrosion/Irritation: Causes moderate to severe irritation. May produce chemical burns upon prolonged contact.
Serious Eye Damage/Irritation: Causes severe eye burns, risk of blindness.
Respiratory Sensitization: Possible mild irritation to mucous membranes.
Chronic Effects: Long-term exposure not well studied; avoid repeated skin contact.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classified as carcinogenic or mutagenic; no data on reproductive toxicity.
Symptoms of Exposure: Nausea, abdominal pain, headache, skin redness, eye pain, breathing difficulty.
Ecotoxicity: Toxic to aquatic life. Fish LC50 (96h): 0.27 mg/L (Zebra fish, Danio rerio).
Persistence and Degradability: Not readily biodegradable in aquatic environments.
Bioaccumulative Potential: Possible, due to moderate log Kow.
Mobility in Soil: May bind to soil, risk of leaching to water bodies.
Other Adverse Effects: Use caution to avoid environmental release. Affects sewage and water treatment biological activity.
Methods of Disposal: Dispose of waste in accordance with local, regional, national, and international regulations.
Incineration: Suitable for high-temperature incineration at approved facilities.
Packaging Disposal: Use safe chemical waste containers, rinse thoroughly before reuse or disposal.
Environmental Precautions: Prevent entry into sewers, drains, and natural water sources.
UN Number: 2811
UN Proper Shipping Name: Toxic Solid, Organic, N.O.S. (Cetylpyridinium Bromide)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions for Transport: Avoid moisture, protect containers from physical damage; follow safety regulations for toxic chemicals in transit.
Regulatory Requirements: Adhere to ADR, IMDG, IATA guidelines as appropriate for destination and route.
TSCA Status (US): Listed on Toxic Substances Control Act inventory
EINECS/ELINCS (Europe): Listed
DSL (Canada): Listed
REACH Registration (Europe): Subject to REACH if over threshold quantities.
Hazard Communication: Subject to OSHA Hazard Communication Standard (HCS 29 CFR 1910.1200)
Other Regulations: Check national and local requirements for workplace controls and environmental release compliance.
Label Elements: Compliant with GHS and CLP requirements
