Chemical Name: Ethyl 4-Bromobutyrate
Synonyms: Butanoic acid, 4-bromo-, ethyl ester
CAS Number: 2969-81-5
Recommended Use: Laboratory chemical, manufacturing intermediate
Manufacturer: [Manufacturing information required by user]
Contact Information: Emergency phone, supplier address, and responsible party details should be listed by the manufacturer supplying the chemical
GHS Classification: Acute Toxicity (Oral, Inhalation), Skin Irritant, Eye Irritant
GHS Pictograms: Exclamation mark (irritation and/or acute toxicity)
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled; causes skin and eye irritation; may cause respiratory irritation
Precautionary Statements: Avoid breathing vapors; wear personal protective equipment; wash thoroughly after handling; use only outdoors or in well-ventilated areas; if in eyes, rinse cautiously with water
Chemical Name: Ethyl 4-Bromobutyrate
CAS Number: 2969-81-5
Concentration: 95% or higher
Impurities: Trace amounts of related esters and solvents (< 5%) possible, depending on synthesis route
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms appear
Skin Contact: Remove contaminated clothing immediately, wash skin with soap and water for at least 15 minutes, get medical help if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing and get medical attention
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, seek immediate medical help
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide or foam
Unsuitable Extinguishing Media: Direct water jet as this may spread fire
Hazardous Combustion Products: Hydrogen bromide, carbon monoxide, carbon dioxide, possible other toxic fumes
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective clothing
Instructions: Evacuate area, keep upwind, use non-sparking tools, prevent firefighting runoff from entering water systems
Personal Precautions: Evacuate unnecessary personnel, avoid contact with skin/eyes, ventilate area, prevent inhalation of vapors
Environmental Precautions: Prevent entry to sewers, surface water, ground water
Methods for Cleanup: Absorb spill with inert material (sand, vermiculite), place in chemical waste container, clean contaminated surface with detergent and water
Disposal: Dispose of waste in accordance with local, regional, and national regulations
Handling: Use with adequate ventilation, wear protective equipment, avoid inhalation, ingestion, skin and eye contact, prevent vapor formation
Storage: Store in cool, dry, well-ventilated place, keep container tightly closed and in original container, protect from light, heat, ignition sources, incompatible substances (strong oxidizers, acids, bases)
Other Precautions: Avoid prolonged or repeated exposure, label containers clearly, inspect regularly for leaks or degradation
Engineering Controls: Use chemical fume hoods, local exhaust ventilation to control exposure
Respiratory Protection: NIOSH/MSHA approved respirators for handling material outside of closed systems
Skin Protection: Chemically resistant gloves (nitrile or butyl), lab coat, long sleeves
Eye Protection: Chemical splash goggles
Other Protective Equipment: Emergency eyewash and shower should be accessible, wash hands thoroughly after use
Appearance: Colorless to pale yellow liquid
Odor: Ester-like, slightly pungent
Odor Threshold: Not available
pH: Not applicable
Melting Point/Freezing Point: -40°C (approximate)
Boiling Point: 211°C
Flash Point: 91°C (closed cup)
Evaporation Rate: Not available
Flammability: Combustible liquid
Vapor Pressure: 0.28 mmHg at 25°C
Vapor Density: Not available
Relative Density: 1.35 g/cm3 at 20°C
Solubility: Insoluble in water, soluble in organic solvents
Partition Coefficient (n-octanol/water): 1.64 (estimated)
Auto-ignition Temperature: Not available
Decomposition Temperature: Not available
Viscosity: Not available
Chemical Stability: Stable under recommended conditions; degrades when exposed to heat, light, or moisture
Possibility of Hazardous Reactions: May react violently with strong oxidizing agents, acids, bases
Conditions to Avoid: Heat, sparks, open flames, exposure to light or moisture
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide, other toxic fumes during combustion
Acute Toxicity Data: Oral LD50 (rat): 1700 mg/kg (literature); Inhalation LC50, Dermal LD50: not fully established
Skin Corrosion/Irritation: Irritates skin; repeated/prolonged exposure may cause dermatitis
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation
Respiratory or Skin Sensitization: Sensitizing potential not fully characterized
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data available for reproductive effects
Specific Target Organ Toxicity (Single/Repeated): Inhalation may cause respiratory irritation, CNS depression at high doses
Other Effects: Ingestion may cause gastrointestinal distress, CNS symptoms
Ecotoxicity: Data limited; similar esters show moderate aquatic toxicity
Persistence and Degradability: Likely biodegradable but persistence possible due to bromine content
Bioaccumulative Potential: Moderate; log Kow suggests some potential for bioaccumulation
Mobility in Soil: Moderate mobility expected based on chemical properties
Other Adverse Effects: Harmful to aquatic life, should not be released untreated into the environment
Waste Disposal Methods: Collect and dispose as hazardous waste through a licensed chemical disposal contractor
Contaminated Packaging: Dispose of as hazardous waste; do not reuse containers
RCRA Hazardous Waste: Not specifically listed, but treat as hazardous based on toxicity and flammability
Other Recommendations: Follow local, state, and federal regulations for hazardous chemical waste disposal; label and segregate from incompatible materials during temporary storage
UN Number: UN3271
UN Proper Shipping Name: Esters, n.o.s. (Ethyl 4-Bromobutyrate)
Transport Hazard Class: 3 (Flammable Liquids)
Packing Group: III
Environmental Hazards: Harmful to aquatic environment
Special Precautions for Transport: Avoid transport with incompatible substances, secure drums and containers, keep away from sources of ignition
OSHA: Hazardous Chemical according to OSHA Hazard Communication Standard
SARA Title III: Not listed as a Section 302, 304, or 313 chemical
TSCA: Listed in the TSCA inventory
Other Regulations: Subject to chemical safety regulations in EU (REACH), Canada (DSL), and other jurisdictions
Labeling Requirements: Must display GHS pictograms, hazard, and precautionary statements
Right-to-Know: May be subject to state or regional right-to-know reporting rules
