Product Name: Ethyl 4-Iodobutyrate
Synonyms: 4-Iodobutyric acid ethyl ester
CAS Number: 7154-78-1
Recommended Use: Laboratory reagent, chemical synthesis
Supplier Details: Chemical manufacturer or distributor information, including address and contact number
Emergency Telephone: Local poison control center or company emergency hotline
Manufacture Date: Provided by supplier on request
Classification: Flammable liquid, Skin and eye irritant
Hazard Statements: Harmful through skin contact, inhalation, or ingestion. Irritates eyes, skin, and mucous membranes. May cause respiratory tract discomfort.
Pictograms: Flame, Exclamation Mark
Signal Word: Warning
Precautionary Statements: Avoid breathing vapors. Wear eye protection. Handle inside efficient fume hood. Do not eat, drink, or smoke during handling.
Target Organs: Eyes, skin, respiratory system
Chemical Name: Ethyl 4-Iodobutyrate
Molecular Formula: C6H11IO2
Molecular Weight: 242.06 g/mol
Purity: Typically 95% or greater
Impurities: Traces of 4-iodobutyric acid, ethanol contaminants (below threshold limits)
Hazardous Components: Contains no substances present at hazardous concentrations per OSHA or other authority
Eye Contact: Rinse with plenty of water for at least 15 minutes, lifting eyelids occasionally. Seek medical attention immediately if irritation persists.
Skin Contact: Wash exposed area with mild soap and water for at least 15 minutes. Remove contaminated clothing. Seek medical attention if irritation develops.
Inhalation: Move to fresh air. Keep affected person at rest. If breathing difficulty or symptoms persist, get medical help.
Ingestion: Rinse mouth thoroughly with water. Do not induce vomiting. Seek medical attention immediately.
Notes for Medical Personnel: Symptomatic and supportive treatment recommended. Monitor for respiratory or allergic reactions.
Suitable Extinguishing Media: Use carbon dioxide, dry chemical extinguisher, or alcohol-resistant foam.
Unsuitable Extinguishing Media: Do not use high-pressure water jets.
Fire Hazards: Vapors form explosive mixtures with air. Containers may burst under fire conditions.
Protective Equipment: Firefighters need self-contained breathing apparatus and complete protective clothing.
Combustion Products: Carbon monoxide, carbon dioxide, hydrogen iodide, various iodine oxides.
Special Procedures: Cool exposed drums with water spray. Isolate area and use non-sparking tools.
Personal Precautions: Remove ignition sources. Evacuate non-essential personnel. Ventilate area. Avoid inhalation or contact.
Environmental Precautions: Prevent from entering drains, surface water, or soil.
Cleanup Methods: Absorb spill with inert material such as vermiculite or sand. Collect and transfer to approved waste container. Wash spill area with sufficient water. Dispose material per local regulations.
Emergency Procedures: Use appropriate personal protective equipment including gloves, goggles, and fume extraction.
Safe Handling: Wear suitable gloves and goggles. Use in vented laboratory chemical hood. Keep away from sparks, heat, and open flame.
Storage Conditions: Store in well-ventilated, dry, cool place. Keep container tightly closed and properly labeled.
Incompatibilities: Avoid contact with strong oxidizers, acids, or bases.
Storage Temperature: Recommended between 2°C and 8°C. Avoid freezing or excessive heat.
Bulk Storage: Only in corrosion-resistant containers.
Occupational Exposure Limits: No specific exposure limits set for this compound under OSHA or ACGIH.
Engineering Controls: Local exhaust ventilation, chemical fume hood.
Respiratory Protection: Use air-purifying respirator if airborne exposure is possible.
Skin Protection: Protective gloves made from nitrile or neoprene.
Eye Protection: Safety goggles or face shield.
Hygiene Measures: Wash hands thoroughly after handling. No food or drink in working area.
Appearance: Clear to pale yellow liquid
Odor: Faint, ester-like aroma
Melting Point: Not established (typically below 0°C)
Boiling Point: 99–101°C at 15 mmHg
Flash Point: Estimated 85°C (closed cup)
Vapor Pressure: Low at ambient temperature
Solubility: Insoluble in water; miscible with most organic solvents
Density: 1.697 g/cm³ at 25°C
Partition Coefficient (n-octanol/water): Estimated moderately lipophilic
Stability: Stable under recommended conditions
Other Properties: Volatile, forms vapors heavier than air
Chemical Stability: Stable in sealed containers at normal laboratory temperatures.
Conditions to Avoid: Exposure to heat, ignition sources, strong sunlight, moisture.
Incompatible Materials: Strong acid, strong base, oxidizers, reducing agents.
Hazardous Decomposition: Hydrogen iodide, iodine vapors, carbon oxides.
Polymerization: Does not undergo hazardous polymerization.
Acute Toxicity: No comprehensive studies on humans or animals. Potential for skin, eye, and respiratory irritation. Estimated oral LD50 (rat) greater than 2000 mg/kg.
Chronic Toxicity: Data on long-term exposure limited.
Skin and Eye Effects: Causes localized irritation. May lead to redness and swelling.
Sensitization: Not a known sensitizer based on available data.
Carcinogenicity: No data indicating carcinogenic risk.
Other Effects: May cause headaches, dizziness, or nausea if inhaled in high concentrations.
Aquatic Toxicity: Limited specific data, but organoiodine compounds often toxic to aquatic life.
Persistence and Degradability: May persist in the environment. Slow breakdown by chemical or biological means.
Bioaccumulative Potential: May accumulate in aquatic organisms.
Mobility in Soil: Potential mobility in soil; risk of leaching into groundwater.
Other Information: Prevent material from entering waterways to reduce risk to the ecosystem.
Disposal Methods: Collect and store chemical waste in tightly sealed and labeled containers. Disposal through licensed hazardous waste contractor or chemical incineration (with flue gas scrubber).
Contaminated Packaging: Rinse thoroughly. Dispose of according to official regulations.
Environmental Precautions: Prevent release to surface water, soil, or municipal sewage.
UN Number: 2810
Proper Shipping Name: Toxic organic liquid, n.o.s. (Ethyl 4-Iodobutyrate)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Protect from extremes of temperature. Ship as hazardous chemical per local and international requirements.
Labeling: Toxic substance label required.
Safety, Health, and Environmental Regulations: Subject to national and international chemical safety regulations including OSHA Hazard Communication Standard, European REACH, and US TSCA inventory.
Other Regulations: May require reporting to national authorities depending on quantity handled.
Hazard Symbol: GHS07 (exclamation mark) and GHS02 (flame) required on bulk packaging.
Restriction Notices: For laboratory and professional use only. Restricted from sale to the general public.
Chemical Inventories: Listed on major chemical regulatory inventories.
