Product Name: Hexadecyltrimethylammonium Chloride
Synonyms: Cetrimonium Chloride, Cetyltrimethylammonium Chloride
Chemical Formula: C19H42ClN
CAS Number: 112-02-7
Recommended Uses: Used in chemical syntheses, surfactant in laboratories, disinfectants, emulsifier in personal care products
Supplier Information: Name, address, and emergency contact for supplier or manufacturer
Emergency Contact Phone: Contact number for quick incident reporting and expert advice on chemical exposure or accidents
Classification: Acute toxicity (oral, dermal), Skin corrosion/irritation, Eye damage/irritation, Aquatic chronic hazard
Label Elements: Pictograms for Corrosive, Skull & Crossbones, Exclamation Mark, Aquatic Toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed. Causes severe skin burns and eye damage. May be toxic to aquatic organisms. Prolonged exposure can intensify toxicity.
Precautionary Statements: Avoid all contact with eyes and skin. Do not breathe dust, vapors, or spray. Use gloves and eye/face protection. Wash hands and exposed skin after handling. Keep away from food and drink areas.
Chemical Name: Hexadecyltrimethylammonium Chloride
Concentration: 98-100% (dependent on manufacturer and supplier specification)
Impurities: Typical specifications require minimal contaminants; some preparations may contain trace moisture or related quaternary ammonium compounds
Ingredient Identification Numbers: EC Number 203-928-6
Molecular Weight: 320.00 g/mol
Inhalation: Move person to fresh air. Seek medical attention if cough, shortness of breath, or irritation persists.
Skin Contact: Rinse with plenty of water for at least 15 minutes. Remove contaminated clothing. Get medical assistance for burns, redness, or persistent irritation.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if worn; continue rinsing. Immediate medical attention required for pain, redness, or impaired vision.
Ingestion: Do not induce vomiting. Rinse mouth thoroughly with water. Seek immediate medical advice. Do not give anything by mouth to an unconscious person.
Most Important Symptoms & Effects: Burning pain, severe irritation, pain in mouth or throat, vomiting, diarrhea, risk of corrosive injury to eyes, mouth, and airways
Suitable Extinguishing Media: Water spray, dry chemical, alcohol-resistant foam, carbon dioxide
Unsuitable Media: Direct water jet may spread material
Specific Hazards: Emits toxic fumes (hydrogen chloride, nitrogen oxides, carbon oxides) under fire conditions. Risk of containers bursting from heat.
Protective Equipment: Full protective gear, self-contained breathing apparatus required for all fire interventions
Advice for Firefighters: Approach from upwind, evacuate area, avoid inhalation of combustion products, cool containers with water spray
Personal Precautions: Prevent skin and eye contact. Use chemical splash goggles, gloves, protective clothing. Ensure adequate ventilation.
Environmental Precautions: Prevent release into drains, surface water, or soil. Notify environmental authorities in the event of major spillage.
Cleanup Procedures: Absorb with inert material (sand, earth, vermiculite). Place in tightly-sealed chemical waste containers for proper disposal. Wash contaminated area with plenty of water.
Spill Response: Use non-sparking tools. Do not handle damaged containers without protective equipment. Prevent dispersal of dust or aerosols.
Handling: Do not eat, drink, or smoke while working. Use only in a chemical fume hood or well-ventilated space. Wear PPE; avoid raising dust or vapors.
Storage: Store tightly closed in a cool, dry, well-ventilated place, away from acids, oxidizers, and incompatible materials. Segregate from foodstuffs. Keep away from direct sunlight and heat sources.
Compatibility: Keep segregated from strong oxidizing agents and acids.
Special Precautions: Label containers clearly. Use secondary containment for large volumes. Maintain good housekeeping in storage and handling areas.
Occupational Exposure Limits: No established limits for this substance, but minimize exposure as a quaternary ammonium compound.
Engineering Controls: Mechanical exhaust ventilation or local fume extraction systems. Use explosion-proof equipment where dust can accumulate.
Personal Protective Equipment: Chemical-resistant gloves (e.g., nitrile), lab coat or apron, safety goggles or face shield, suitable respirator for dust or vapor exposure.
Hygiene Measures: Wash thoroughly after handling. Remove contaminated clothing before breaks and after work. Maintain eyewash fountains and safety showers near use areas.
Appearance: White or off-white crystalline powder or solid
Odor: Slight amine-like odor
Odor Threshold: Not established
pH: 4.0–7.0 (10% solution in water)
Melting Point/Freezing Point: 232–237°C
Boiling Point: Not available (decomposes)
Flash Point: > 100°C, not readily flammable
Evaporation Rate: Not applicable
Flammability: Not classified as flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: 0.98–1.08 g/cm³
Solubility: Soluble in water, lower alcohols
Partition Coefficient (n-octanol/water): Not determined
Autoignition Temperature: Not established
Decomposition Temperature: Above 230°C, with toxic gas evolution
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Incompatible Materials: Strong oxidizing agents, acids, anionic surfactants
Reactivity: Non-reactive under normal circumstances, but will react with strong oxidizers and acids
Hazardous Decomposition Products: Hydrogen chloride, carbon oxides, nitrogen oxides
Conditions to Avoid: Moisture, heat, open flame, incompatible chemicals
Polymerization: Not expected to occur
Routes of Exposure: Ingestion, inhalation, skin/eye contact
Acute Toxicity: Oral LD50 (rat) approx. 400–500 mg/kg; Harmful if swallowed
Dermal Toxicity: Can cause severe skin irritation and burns
Eye Damage/Irritation: Severe, potentially irreversible
Inhalation: May cause respiratory discomfort, coughing, sore throat
Chronic Effects: Repeated exposure may cause dermatitis, sensitization
Other Effects: May aggravate existing respiratory or skin conditions
Carcinogenicity, Mutagenicity: No classified evidence yet. Not expected to be mutagenic or cancer-causing under usual handling.
Aquatic Toxicity: Very toxic to aquatic organisms; fish LC50 (96h) <1 mg/L
Persistence and Degradability: Not readily biodegradable; can persist in aquatic environments
Bioaccumulative Potential: Moderate; potential to accumulate in aquatic organisms
Mobility: Soluble in water; risk of dispersion in the event of a spill
Other Adverse Effects: Harmful to sewage, wastewater treatment facilities if released untreated
Waste Disposal: Dispose of in accordance with local, regional, and national regulations. Use licensed chemical waste disposal contractor.
Contaminated Packaging: Triple rinse containers and submit to chemical waste collection, or puncture and dispose of in landfill if permitted.
Special Precautions: Do not release into environment. Label waste clearly. Segregate from regular waste streams.
UN Number: 2815
UN Proper Shipping Name: N,N,N-Trimethyl-1-hexadecanaminium chloride
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: III
Marine Pollutant: Yes
Special Transport Precautions: Ensure packaging prevents leaks; carriers must be aware of potential for environmental harm. Emergency response information must accompany shipment.
OSHA: Regulated as hazardous
TSCA Inventory: Listed
REACH Registration: Registered in European Union
WHMIS Classification: Corrosive material
Inventory Listings: Listed on EINECS/ELINCS, AICS, DSL/NDSL
Other Regulations: Subject to additional local, national, or international chemical control measures. Notification required for use in certain applications.
Labeling: Must display hazard, precaution, and emergency contact information per GHS guidelines.
