Product Name: Hexadecyltriphenylphosphonium Bromide
Chemical Formula: C34H46BrP
CAS Number: 68299-14-9
Synonyms: 1-Hexadecyltriphenylphosphonium Bromide
Recommended Use: Research and industrial chemical, phase transfer catalyst, antimicrobial agent
Supplier Information: Manufacturer/distributor contact details (address, phone, fax, emergency contact), reference to safety officer for workplace distribution
Product Code: Specific identifier corresponding to manufacturer’s product range
Main Hazards: Causes skin and eye irritation, may cause respiratory discomfort if inhaled, toxic if swallowed, hazardous to aquatic life
GHS Classification: Acute Toxicity (Oral, Category 3), Skin Irritant (Category 2), Eye Irritant (Category 2A), Hazardous to Aquatic Environment (Acute & Chronic, Category 1)
Signal Word: Danger
Hazard Statements: Harmful if ingested, irritating to skin and eyes, respiratory tract irritation possible, very toxic to aquatic organisms, long-lasting effects on environment
Pictograms: Exclamation mark, health hazard, environmental hazard
Precautionary Statements: Prevent release to waterways, avoid skin and eye contact, do not breathe dust, wash hands thoroughly after handling, wear protective clothing
Chemical Name: Hexadecyltriphenylphosphonium Bromide
Concentration: ≥98% (typically pure form for lab or industrial use)
CAS Number: 68299-14-9
Impurities: Very low, any impurities must be listed by supplier for accuracy
Inhalation: Move exposed person to fresh air, keep at rest, monitor for signs of respiratory distress, seek medical advice if symptoms persist or worsen
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of water and soap, do not use solvents, seek medical attention for persistent irritation
Eye Contact: Rinse immediately with plenty of water, lifting upper and lower eyelids occasionally, remove contact lenses if worn and easy to do, continue rinsing for at least 15 minutes, seek prompt medical assessment
Ingestion: Rinse mouth, do not induce vomiting, offer small amount of water if conscious, never give anything by mouth to a person losing consciousness or convulsing, immediate medical attention required
Advice for Physicians: Treat symptomatically, monitor respiratory, cardiovascular, and neurological function, provide supportive care as indicated by symptoms
Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or foam
Unsuitable Extinguishing Media: Avoid direct water jets as chemicals may spread
Hazardous Combustion Products: Release of carbon monoxide, carbon dioxide, phosphorous oxides, bromine fumes, and potentially toxic organic vapors during combustion
Special Protective Equipment for Firefighters: Wear full protective suit, self-contained breathing apparatus (SCBA), chemical resistant gloves, and footwear
Firefighting Instructions: Approach fire from upwind, contain runoff to prevent environmental contamination, cool exposed containers with water spray
Flash Point: Data not commonly available but handled as combustible material
Personal Precautions: Evacuate non-essential personnel, avoid inhalation and skin contact, ensure adequate ventilation, wear appropriate protective gear (gloves, goggles, respirator)
Environmental Precautions: Prevent spillage from entering drains, sewers, waterways, or soil, use physical barriers (sand, earth)
Methods for Cleanup: Collect spillage using non-sparking tools, absorb with inert material (sand, vermiculite), sweep into suitable chemical waste container, label and dispose as hazardous waste
Decontamination Procedures: Wash affected area with soap and water, ventilate room, wash cleanup materials before reuse or disposal
Safe Handling: Avoid contact with skin, eyes, clothing, do not inhale dust, use in fume hood or well-ventilated space, do not eat, drink, or smoke near usage areas, use personal protective equipment at all times
Storage Conditions: Store in tightly closed original container, cool dry place, protect from moisture, strong acids, bases, and oxidizers, keep away from incompatible substances
Special Requirements: Clearly label containers, secure to avoid accidental damage, restrict access to authorized personnel, routinely check for signs of deterioration or leakage, ground storage area to reduce static discharge risk
Engineering Controls: Use local exhaust ventilation or chemical fume hood for dusty or powdered forms, maintain eyewash stations and safety showers nearby
Exposure Limits: No specific occupational exposure limit established, treat as hazardous substance
Respiratory Protection: Use NIOSH-approved respirator (full-face or half-mask) in the absence of ventilation, especially during spill response or handling large quantities
Hand Protection: Chemical-resistant gloves (nitrile, neoprene)
Eye Protection: Chemical safety goggles and/or face shield
Skin and Body Protection: Lab coat, apron, long sleeves, closed-toe shoes, avoid synthetic fabrics that may trap particles
Hygiene Measures: Wash hands and any exposed skin after handling, remove contaminated clothing immediately, do not reuse until cleaned
Appearance: White to off-white crystalline powder
Odor: Odorless or faint organic odor
Molecular Weight: 577.6 g/mol
Melting Point: 236–245°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, alcohols, and polar organic solvents
Density: ~1.28 g/cm3 (at 20°C)
pH: Not applicable (Neutral solution in water)
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Not established
Viscosity: Not relevant for solid state
Explosive Properties: Not considered explosive
Flammability: Not classified as flammable, combustible at high temperatures
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: May react with strong oxidizers, strong acids, and some halogenated compounds
Conditions to Avoid: High humidity, strong heat sources, open flames, incompatible chemicals
Decomposition Products: Releases toxic gases (CO, CO2, Br2, P-oxides) when heated to decomposition
Polymerization: No hazardous polymerization expected
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Data suggests LD50 (oral, rat) between 50–300 mg/kg (toxicity varies by source)
Symptoms of Exposure: Eye and skin irritation, nausea, vomiting, abdominal pain, cough, sore throat, possible respiratory distress
Chronic Effects: No long-term studies in humans, repeated exposure may irritate respiratory system and skin
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No classification as carcinogen or mutagen based on available sources
Other Health Effects: Not known to be sensitizer but recommend caution due to potential phosphonium compound reactivity
Ecotoxicity: Highly toxic to aquatic organisms (notably fish, daphnia, and algae), strong bioaccumulation potential in aquatic environments, no targeted studies on terrestrial wildlife identified
Mobility in Soil: Moderately mobile, depends on soil type and organic content
Persistence and Degradability: Expected to be persistent in water and soil due to low biodegradability
Bioaccumulation: Likely potential based on molecular structure and affinity for organic matter
Environmental Precautions: Avoid release into environment, prevent chemical from migrating into groundwater or sewage systems
Waste Treatment Methods: Dispose of all waste and contaminated containers as hazardous chemical waste in accordance with local, state, national, and international regulations
Recommended Disposal Process: Chemical incineration in approved facility, do not pour down drain, consult waste handler or environmental health professional
Contaminated Packaging: Rinse containers before disposal if allowed, otherwise treat as hazardous waste, label and secure until removed
Precautions: Follow all legal requirements, include proper documentation for shipped hazardous waste
UN Number: Not assigned a specific UN number; consult shipping provider for latest guidance
UN Proper Shipping Name: Chemical, N.O.S. (not otherwise specified; Hexadecyltriphenylphosphonium Bromide)
Transport Hazard Class(es): Consult local authorities, typical hazard class 6.1 (Toxic substances)
Packing Group: III (where regulated)
Environmental Hazards: Marine pollutant
Special Precautions: Pack in tightly sealed, compatible container; clearly label contents and hazards; restrict movement to minimize spills or leaks; provide safety paperwork during transit
Regulatory References: Cross-check with IMDG, IATA, and ADR transport codes before shipment
Labeling Requirements: GHS-compliant labels showing hazard pictograms, signal words, hazard statements, precautionary statements, and supplier information
TSCA Status (US): Ensure substance meets all import and usage controls per EPA
REACH Status (EU): Substance must comply with registration and notification procedures
Other Regulatory Information: Controlled under various chemical safety and environmental laws; subject to workplace health and safety codes
Training Recommendations: Handlers, transporters, and disposal teams should receive proper chemical safety, emergency response, and waste management instruction
Inventory Listings: Confirm listing and regulatory compliance before import, export, or distribution in each jurisdiction
