Product Name: Methyl 6-Chlorohexanoate
Chemical Formula: C7H13ClO2
Synonyms: 6-Chlorohexanoic acid methyl ester
CAS Number: 6293-23-6
Recommended Use: Intermediate for organic synthesis, pharmaceutical compounds, and chemical research
Manufacturer/Supplier: Contact details provided on purchase or delivery documentation
Emergency Contact Number: Refer to local guidelines for poison control center or emergency services
GHS Classification: Flammable liquid, Acute oral toxicity, Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation; harmful if swallowed or inhaled; vapor may cause drowsiness and dizziness
Precautionary Statements: Avoid breathing vapors; wear protective gloves, clothing, and eye/face protection; keep away from heat, sparks, and open flames
Hazard Symbols: Exclamation mark, Health hazard
Routes of Exposure: Dermal, inhalation, ingestion
Target Organs: Skin, eyes, respiratory tract
Chemical Name: Methyl 6-Chlorohexanoate
Concentration: >98% by weight
Impurities: Trace amounts of related chlorinated hexanoates or unreacted starting materials below quantifiable limits
Other Ingredients: None significant
If Inhaled: Move affected person to fresh air immediately; seek medical attention if symptoms develop such as coughing, nausea, or difficulty breathing
If on Skin: Remove contaminated clothing, wash exposed skin with plenty of soap and water for at least 15 minutes; seek medical attention if irritation persists
If in Eyes: Rinse thoroughly under running water for at least 15 minutes, lifting eyelids occasionally; seek immediate medical care
If Swallowed: Rinse mouth with clean water; do not induce vomiting; seek urgent medical attention
Notes for Medical Personnel: Treat symptomatically; monitor for respiratory distress and skin or eye irritation
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, alcohol-resistant foam
Unsuitable Extinguishing Media: Strong water jet, as this may spread the fire
Fire Hazards: Emits toxic fumes of hydrogen chloride and carbon oxides under combustion
Protective Equipment: Self-contained breathing apparatus and full protective gear for firefighters
Advice for Firefighters: Remove containers from area if safe; cool fire-exposed containers with water spray; prevent contaminated water runoff from entering drains or watercourses
Personal Precautions: Avoid inhalation of vapors and contact with skin or eyes; ventilate area; evacuate unprotected personnel
Emergency Procedures: Isolate spill area; keep unauthorized personnel away; eliminate ignition sources
Environmental Precautions: Prevent release to environment, especially waterways and drains
Clean-Up Methods: Absorb spill with inert material (sand, vermiculite); collect residue and place in a labeled container for disposal; ventilate area thoroughly
Decontamination: Wash spill site after material pickup is complete
Safe Handling: Use only in well-ventilated areas; avoid contact with skin, eyes, and clothing; keep containers tightly closed; ground and bond containers when transferring liquid
Storage Conditions: Store at room temperature in a dry, cool, well-ventilated place; keep container tightly sealed; protect from direct sunlight, sources of ignition, and incompatible materials such as strong oxidizers
Storage Class: Flammable liquids and organic chemicals
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Engineering Controls: Provide good general ventilation; use local exhaust or fume hood where possible; provide safety shower and eye wash station in work area
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, lab coat or apron, and appropriate respiratory protection in case of inadequate ventilation
Exposure Limits: No established OSHA, ACGIH, or other regulatory exposure limits specifically for methyl 6-chlorohexanoate; general nuisance limits for organic vapors may apply
Hygiene Measures: Do not eat, drink, or smoke in work area; wash hands thoroughly after handling; remove contaminated clothing before entering eating areas
Appearance: Colorless to pale yellow liquid
Odor: Mild, ester-like
Molecular Weight: 164.63 g/mol
Boiling Point: 213-215°C at atmospheric pressure
Melting Point: Not applicable (liquid at room temperature)
Flash Point: 92°C (closed cup, approximate)
Auto-ignition Temperature: Not determined
Vapor Pressure: Low at room temperature
Solubility: Low solubility in water, soluble in organic solvents like ethanol and acetone
Density: 1.08 g/cm³ at 20°C
pH: Not applicable
Partition Coefficient (n-octanol/water): Data not available
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Not reactive under normal use
Possible Hazardous Reactions: Will not polymerize; reacts with strong oxidizers to produce heat and hazardous products
Conditions to Avoid: Heat, flames, sparks, static discharge, direct sunlight
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide when heated to decomposition
Acute Toxicity: Oral toxicity suspected based on structural analogy, estimated LD50 (rat) 500-2000 mg/kg
Skin Corrosion/Irritation: May cause moderate skin irritation
Eye Damage/Irritation: Causes red, painful eyes, possible temporary blurred vision or irritation
Respiratory Sensitization: Vapors may irritate respiratory tract
Chronic Effects: No data for chronic toxicity, mutagenicity, carcinogenicity, or reproductive toxicity; cautious interpretation required
Inhalation: Exposure to high vapor concentrations may cause health effects such as headache, dizziness, tiredness, nausea, confusion
Routes of Entry: Skin, eyes, inhalation, ingestion
Symptoms of Exposure: Skin redness, burning eyes, coughing, respiratory discomfort, abdominal discomfort if swallowed
Ecotoxicity: Expected to have moderate toxicity to aquatic life due to chlorinated alkyl ester structure
Persistence and Degradability: Not readily biodegradable, long-term effects in water and soil possible
Bioaccumulation Potential: May have potential to bioaccumulate based on chemical properties
Mobility in Soil: May bind to soils and sediment due to moderate hydrophobicity, but some leaching possible
Other Adverse Effects: Avoid release to the environment; harmful to aquatic organisms in even small quantities
Relevant Legislation: Must follow national guidelines for discharge and disposal
Waste Disposal Methods: Collect and dispose under guidance of local, regional, or national regulations; incineration in approved facility recommended
Contaminated Packaging: Triple-rinse empty containers; puncture and dispose in accordance with local hazardous waste requirements
Precautions for Disposal: Do not pour into drains, watercourses, or soil; label and store waste in chemical-resistant, sealable containers for licensed waste handler
Special Handling: Personnel handling waste must use proper PPE and avoid inhalation or contact during packaging and transfer for disposal
UN Number: 3271
UN Proper Shipping Name: Esters, n.o.s. (Methyl 6-Chlorohexanoate)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labels Required: Flammable liquid
Environmental Hazards: Not classed as marine pollutant under IMDG
Special Precautions for User: Keep away from ignition sources; use grounding/bonding while in transit; secure tightly during handling to avoid leaks
Safety, Health, and Environmental Regulations: Listed or regulated under local and national chemical control laws; handle and store according to occupational health and safety legislation
OSHA Hazard Status: Hazardous Chemical as defined by OSHA Hazard Communication Standard
TSCA Inventory: Listed or status to be confirmed by supplier
SARA Title III: Not listed as an extremely hazardous substance; not subject to Section 313 reporting
REACH: May require notification or registration under European REACH legislation
Other Regulations: Comply with all industry, state, and country-specific regulations for hazardous substances; proper labeling and documentation required for storage, handling, and transportation
