Material Safety Data Sheet: N-Ethyl-N-Methylpyrrolidinium Bromide

1. Identification

Product Name: N-Ethyl-N-Methylpyrrolidinium Bromide
Chemical Formula: C7H16BrN
Chemical Family: Pyrrolidinium Salt
Recommended Use: Laboratory, research, and chemical synthesis applications
Manufacturer: Supplied by chemical manufacturers and laboratory supply firms.
Emergency Contact: Refer to supplier emergency phone line or local poison control center.

2. Hazard Identification

Classification: Irritant to eyes, skin, and respiratory tract; harmful if swallowed or inhaled
Hazard Statements: Causes skin and serious eye irritation; may cause respiratory irritation
Pictograms: Exclamation mark (irritant), health hazard
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Potential Health Effects: Shortness of breath, coughing, burning sensation on skin and eyes, possible headache or nausea on inhalation
Precautionary Statements: Avoid breathing dust or vapors; wash hands thoroughly after handling; use only outdoors or in a well-ventilated area; wear protective gloves, clothing, and eye protection

3. Composition / Information on Ingredients

Chemical Identity: N-Ethyl-N-Methylpyrrolidinium Bromide
CAS Number: 1119-20-0
EC Number: 214-280-6
Concentration: 99% or higher in supplied form
Impurities: Trace organic/inorganic contaminants (<0.5%), typically unreported unless specified on batch analysis

4. First Aid Measures

Inhalation: Move person to fresh air; seek medical advice if symptoms persist; provide oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing; rinse skin with large amounts of water for at least 15 minutes; seek medical attention for irritation
Eye Contact: Rinse immediately with water for several minutes, remove contact lenses if present and easy to do; seek medical attention
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical attention immediately
Note to Physician: Treat symptomatically; monitor airway and vital signs

5. Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray for larger fires
Specific Hazards: Thermal decomposition releases irritant and possibly toxic gases (such as hydrogen bromide, nitrogen oxides, carbon oxides)
Special Protective Equipment: Firefighters should wear full protective gear, including self-contained breathing apparatus
Firefighting Procedures: Prevent runoff from entering drains, waterways, or soil; cool containers with water spray

6. Accidental Release Measures

Personal Precautions: Wear gloves, protective goggles, and mask to prevent dust inhalation or skin contact
Environmental Precautions: Prevent material from entering sewers, water sources, and soil
Cleanup Methods: Sweep up using non-sparking tools; place in suitable, labeled containers for disposal; ventilate area and wash spill site after material pickup
Decontamination: Wash all equipment and surfaces thoroughly with water and detergent after spill cleanup

7. Handling and Storage

Safe Handling Advice: Work in a chemical fume hood; avoid breathing dust and direct contact with skin or eyes; handle in accordance with good industrial hygiene and safety practices
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated area away from incompatible substances, such as strong oxidizers and acids; protect from light and moisture
Incompatible Materials: Strong oxidizing agents, acidic or basic reagents
Packing Material: Use plastic or glass containers with appropriate chemical resistance

8. Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established; minimize exposure as much as possible
Engineering Controls: Use fume hoods, exhaust ventilation, or laboratory-grade ventilation to control airborne concentrations
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), lab coat, safety goggles or face shield; use dust mask or respirator if airborne dust is present
Hygiene Measures: Wash hands, arms, and face thoroughly before eating, drinking, or leaving work area; avoid touching face with contaminated gloves or hands

9. Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Odorless or slight amine-like smell
Molecular Weight: 210.12 g/mol
Melting Point: Approx. 190-200°C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water and polar organic solvents
Vapor Pressure: Not applicable (solid at standard conditions)
Density: Approx. 1.3 g/cm³
pH: 5–8 (5% aqueous solution at 20°C)
Partition Coefficient (n-octanol/water): Not determined
Flash Point: Not flammable at standard conditions
Other Properties: Stable under recommended storage conditions

10. Stability and Reactivity

Chemical Stability: Stable under normal handling and storage conditions
Conditions to Avoid: High temperatures, exposure to light, moisture
Incompatible Materials: Oxidizing and reducing agents, acidic or basic conditions can degrade product
Hazardous Decomposition Products: Hydrogen bromide, nitrogen oxides, carbon oxides may form under fire or intense heat
Polymerization: No hazardous polymerization expected

11. Toxicological Information

Acute Toxicity: Limited data; similar compounds can have oral LD50 in rats above 2000 mg/kg
Routes of Exposure: Skin contact, inhalation, ingestion, eye contact
Irritation/Corrosion: Mechanical and possibly chemical irritation to skin, eyes, respiratory tract
Symptoms: Redness, pain, watering of eyes, cough, headache, dizziness
Chronic Effects: No long-term toxicity studies reported; avoid repeated or prolonged exposure
Carcinogenicity: Not classified as carcinogenic; no animal or human data available
Mutagenicity/Teratogenicity: Not tested; handle as a potential mutagenic material for laboratory safety

12. Ecological Information

Aquatic Toxicity: Expected to be moderately toxic to aquatic organisms based on chemical class; specific data not available
Environmental Persistence: Compound may degrade slowly; soluble in water, potentially mobile; limited data on bioaccumulation
Effect on Microorganisms: May alter microbial activity at high concentrations
Soil Mobility: Likely mobile in soil due to water solubility
Other Adverse Effects: Minimize discharge into environment to avoid harm to wildlife and water systems

13. Disposal Considerations

Disposal Methods: Collect in properly labeled containers; dispose of as hazardous chemical waste through licensed disposal contractor
Waste Codes: Not defined; classify as laboratory chemical waste
Precautions: Do not release into drains, surface water, or soil; avoid contact with incompatible wastes
Contaminated Packaging: Triple rinse; dispose or recycle according to local regulations

14. Transport Information

UN Number: Not assigned
Proper Shipping Name: N-Ethyl-N-Methylpyrrolidinium Bromide (chemical, non-hazardous for transport under standard regulations)
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Label Requirements: General laboratory chemical labeling required
Special Precautions: Secure containers to prevent spillage; shield from moisture and heat during transport

15. Regulatory Information

International Inventory Status: Not listed on most major chemical inventories (TSCA, EINECS, DSL) – check local requirement
OSHA Hazard Communication: Considered hazardous
SARA Title III (Sections 311/312): Classified as an acute health hazard
WHMIS (Canada): D2B (Toxic material causing other effects)
EPA Regulations: Not regulated as a specific environmental hazard
State Regulations: Subject to workplace right-to-know laws in some US states
Other Regulations: Conform to workplace safety programs, lab safety standards, and chemical hygiene protocols