Product Name: N-Ethylpyridinium Hydrogen Sulfate
Chemical Formula: C7H10NO4S
Synonyms: 1-Ethylpyridinium Hydrogensulfate, NEPHS
Recommended Use: Laboratory reagent, ionic liquid, catalyst
Supplier Details: Refer to manufacturer’s label
Emergency Number: Available from local health and safety authority
Classification: Corrosive to skin and eyes; risk of respiratory irritation
Pictograms: Corrosive, Exclamation mark
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage; may cause respiratory tract irritation
Precautionary Statements: Avoid breathing dust or mist, wear suitable protective clothing, wash hands after handling, do not eat or drink when using the chemical
Other Hazards: Reacts strongly with bases, releases toxic gases when heated
Chemical Name: N-Ethylpyridinium hydrogen sulfate
CAS Number: 477486-52-3
EC Number: Not assigned
Concentration: 98% or greater
Impurities: Trace pyridine compounds, water
General Advice: Move person to fresh air, remove contaminated clothing
Eye Contact: Rinse with plenty of water for at least 15 minutes, seek medical help promptly
Skin Contact: Wash with soap and water, get urgent medical attention for any sign of burn or irritation
Inhalation: Move to fresh air immediately, assist breathing as needed, call emergency services
Ingestion: Rinse mouth, do not induce vomiting, seek medical assistance straight away
Most Important Symptoms: Burning sensation, redness, severe eye or skin irritation, cough, shortness of breath
Medical Attention: Treatment supportive, monitor for delayed symptoms
Extinguishing Media: Use dry chemical, carbon dioxide, or foam; avoid water jet
Hazards from Combustion: Releases toxic and corrosive sulfur oxides, nitrogen oxides; dense smoke possible
Protective Equipment: Wear full protective gear, including breathing apparatus
Firefighting Advice: Evacuate area, use water spray to cool cans, prevent runoff into water bodies
Special Procedures: Remove containers from fire zone if safe, avoid inhalation of fumes
Personal Precautions: Wear chemical-resistant gloves, eye protection, long sleeves
Environmental Precautions: Prevent spillage entering drains, soil, watercourses
Spill Cleanup: Contain and collect using inert absorbents like sand, shovel into suitable labeled containers for disposal
Decontamination: Wash area with plenty of water, ventilate space, remove contaminated materials appropriately
Small Spills: Use neutralizing agent compatible with acid spills
Large Spills: Alert emergency services, evacuate, control area access
Safe Handling: Avoid direct contact, never inhale dust or vapor, handle in a fume hood if possible
Storage Conditions: Keep in tightly closed, corrosion-resistant containers, store at room temperature in a cool, dry, well-ventilated location
Incompatibles: Keep away from strong bases, oxidizers, reduce agents, water-reactive materials
Other Advice: Label all containers clearly, use secondary containment
Exposure Limits: No specific OSHA or ACGIH limits established for this compound
Engineering Controls: Work in a chemical fume hood or with local exhaust ventilation
Personal Protective Equipment (PPE): Wear gloves (nitrile or butyl rubber), chemical splash goggles, face shield, lab coat
Respiratory Protection: Use approved respirator if exposure risk exists
Hygiene Practices: Wash hands thoroughly after use, do not eat or drink in work area, remove contaminated clothing before exiting the lab
Appearance: White to off-white crystalline powder
Odor: Slight ammonia or sulfur
Odor Threshold: Not established
pH: Strongly acidic in solution
Melting Point/Freezing Point: 95–103°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not determined
Flammability: Not flammable
Explosive Limits: No data
Vapor Pressure: Negligible
Vapor Density: Not available
Solubility: Soluble in water and some polar solvents
Partition Coefficient: Not available
Auto-ignition Temperature: No data
Decomposition Temperature: About 200°C, releases toxic fumes
Viscosity: Not determined
Molecular Weight: 191.22 g/mol
Chemical Stability: Stable under normal laboratory conditions in original packaging
Hazardous Reactions: May react with strong bases and oxidizing agents, can release irritating sulfur dioxide gas under heat
Conditions to Avoid: Exposure to moisture, extreme temperatures, open flame
Materials to Avoid: Strong alkalis, strong oxidizers, reducing materials
Hazardous Decomposition Products: Emits nitrogen oxides, sulfur oxides, and toxic organic vapors if decomposed
Polymerization: Not reported to undergo hazardous polymerization
Acute Toxicity: Data limited; expected to cause burns to skin, eyes, and mucous membranes
Skin Corrosion/Irritation: Corrosive on contact, may cause deep tissue damage
Serious Eye Damage/Irritation: Severe, can lead to vision impairment
Respiratory Sensitization: Vapor and dust may cause respiratory tract irritation, cough, difficulty breathing
Ingestion: Causes burns to mucous membranes, nausea, vomiting, abdominal pain
Chronic Effects: Repeated exposure may result in dermatitis, chronic respiratory issues
Carcinogenicity: No IARC, NTP, or OSHA classification
Mutagenicity and Reproductive Toxicity: No data available
Ecotoxicity: Expected to be toxic to aquatic life due to its acidity and pyridine structure
Persistence and Degradability: Limited information, not expected to degrade rapidly in environment
Bioaccumulation Potential: Not anticipated to bioaccumulate significantly
Mobility in Soil: Likely mobile in water, may acidify soils and waterways
Other Adverse Effects: Alters pH of environments, harmful to flora and fauna with prolonged release
Disposal Methods: Send to approved chemical waste disposal facility, follow local, regional, and national regulations
Container Disposal: Triple rinse and offer container for recycling or reconditioning where possible, otherwise treat as hazardous waste
Contaminated Packaging: Handle as hazardous material
Special Precautions: Do not dispose of unused product or solutions down the drain
UN Number: Not assigned; consult regulations for acids of similar classification
UN Proper Shipping Name: Consult shipping guidelines for acids, irritation risk
Hazard Class: 8 (Corrosive substances)
Packing Group: II or as specified by shipping authority
Transport Labelling: Corrosive label required
Marine Pollutant: Not specifically identified but should be shipped with precaution due to ecological hazard
Special Transport Measures: Ensure containers remain upright, secured, adequately labeled
OSHA: Not regulated specifically, general chemical safety applies
TSCA: Check inventory status; may require EPA notification
SARA Title III: Not listed for sections 302, 304, 313; chemical release reporting may apply in event of large exposure
REACH: Registration may be required for manufacture or import into the EU
Labeling: Must include hazard warnings, handling instructions, PPE recommendations
Other National/International Regulations: Follow country-specific requirements including workplace exposure and environmental restrictions
Product Restrictions: Intended for use by qualified professionals in laboratory or industrial settings, not for consumer use
