Product Name: N-Octyl Pyridinium Bromide
Chemical Formula: C14H24BrN
CAS Number: 2564-82-1
Synonyms: 1-Octylpyridinium Bromide, NOPBr
Manufacturer: Chemical suppliers and distributors, often research or specialty labs
Recommended Use: Laboratory reagent, surfactant, phase transfer catalyst
Restrictions on Use: Use only in professional settings and not for drug, food, or cosmetic applications
Classification (GHS): Acute Toxicity (Oral, Dermal, Inhalation), Eye Irritation, Skin Irritation, Hazardous to the Aquatic Environment
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes serious eye irritation; Causes skin irritation; Toxic to aquatic life
Pictograms: Exclamation mark, Environment hazard
Precautionary Statements: Avoid contact with skin and eyes; Do not ingest or inhale; Use only outdoors or in a well-ventilated area; Avoid release to the environment; Wash hands thoroughly after handling
Symptoms of Exposure: May produce coughing, shortness of breath, nausea, skin redness, tearing, and respiratory tract irritation
Chemical Name: N-Octyl Pyridinium Bromide
Concentration: Pure compound, usually above 98% when supplied for lab use
Impurities: Potential trace levels of octyl pyridine derivatives, solvent residues depending on manufacturer
CAS Number: 2564-82-1
EC Number: 219-887-3
Molecular Weight: 286.25 g/mol
General Advice: Expose person to fresh air, seek medical attention if symptoms appear
Inhalation: Remove person from exposure, provide fresh air, keep at rest, seek immediate medical help in case of breathing difficulty
Skin Contact: Remove contaminated clothing, wash skin with plenty of soap and water for several minutes, seek medical attention for persistent irritation
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing and seek prompt medical attention
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, seek medical attention if feeling unwell or after intake of large amounts
Most Important Symptoms: Respiratory or skin sensitization, irritation, shortness of breath, red eyes, gastrointestinal upset
Notes for Healthcare Providers: Treat symptomatically, monitor respiratory and gastro-intestinal systems
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide to extinguish
Unsuitable Extinguishing Media: Direct water jet with high pressure may spread material
Specific Hazards: Emits toxic fumes under fire conditions such as hydrogen bromide, nitrogen oxides, pyridine derivatives
Protective Equipment for Firefighters: Full protective suit, positive pressure self-contained breathing apparatus
Advice for Firefighters: Move containers away from fire area, cool unopened containers with water mist, prevent runoff to drains and waterways
Personal Precautions: Evacuate unnecessary personnel, ensure adequate ventilation, use personal protective equipment including gloves, lab coat, eye protection, and respirator if dust or fumes detected
Environmental Precautions: Keep from entering drains, surface water, and soil
Containment Methods: Collect spillage using non-sparking tools, absorb with inert material such as sand, and transfer to a labeled container
Cleaning Up: Sweep up and shovel, avoid generating dust, thoroughly ventilate area and dispose of collected material promptly
Handling: Handle in a fume hood or well-ventilated area, avoid breathing dust, avoid contact with skin, eyes, and clothing, use proper protective gear
Storage Conditions: Store in tightly closed containers in a cool, dry, ventilated, and light-protected area designed for chemicals, segregate from oxidizers and acids
Packaging Materials: Use glass or high-density polyethylene containers compatible with bromide and organic materials
Hygiene Practices: Wash hands, face, and other exposed areas after handling and before eating, drinking, or smoking
Engineering Controls: Use local exhaust ventilation, fume hood recommended, equipment easily cleaned in case of spills
Personal Protective Equipment: Nitrile gloves, splash proof goggles, protective clothing, NIOSH approved respirator if dust forms
Occupational Exposure Limits: No official limits specifically set for N-Octyl Pyridinium Bromide; keep airborne concentrations as low as possible, rely on general safe limits for laboratory chemicals (as per local guidelines and regulations)
Environmental Exposure Controls: Prevent release into environment, use containment for spills and waste
Appearance: White to off-white crystalline powder
Odor: Mild pyridine or amine-like scent
Melting Point: 78–82°C (172–180°F)
Boiling Point: Decomposition before boiling
Solubility: Soluble in water, alcohols, organic solvents
pH (1% solution): Slightly acidic to neutral
Vapor Pressure: Negligible at room temperature
Density: 1.2–1.3 g/cm3
Flash Point: Not flammable under standard lab conditions
Partition Coefficient (log Kow): Not well documented
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: No dangerous reactions expected under normal use
Conditions to Avoid: Strong heat, light exposure, sources of ignition, incompatible substances
Incompatible Materials: Strong oxidizers, acids, bases
Decomposition Products: Hydrogen bromide, pyridine compounds, nitrogen oxides
Likely Routes of Exposure: Skin and eye contact, inhalation of dust, accidental ingestion
Acute Toxicity: Moderate by oral, dermal, or inhalation routes; animal studies indicate LD50 (oral, rat) in range of 50–300 mg/kg
Skin Corrosion/Irritation: May cause redness, itchiness, and burning sensation
Eye Damage/Irritation: Provokes serious irritation, tearing, or damage with direct contact
Respiratory Effects: Cough, throat irritation, shortness of breath
Sensitization: No substantial data for allergic sensitization, but caution is warranted
Chronic Effects: Limited long-term studies; repeated or prolonged exposure should be avoided as a precaution
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classified as carcinogen by major agencies; limited data available so minimize exposure
Ecotoxicity: Harmful to aquatic organisms, may cause long-lasting adverse effects in the aquatic environment
Persistence and Degradability: Slow degradation in soil and water, possible accumulation in aquatic sediments
Bioaccumulative Potential: Likely to bioaccumulate in aquatic species due to molecular structure
Mobility in Soil: Moderate in aqueous environments, may migrate through soil and water systems
Other Adverse Effects: Avoid uncontrolled release into the environment, bioaccumulation threatens local food chains and ecosystems
Waste Treatment Methods: Dispose as hazardous waste according to local, national, and international regulations
Product Disposal: Do not allow product or washings to enter watercourses, drains, or soil; incinerate only in properly permitted facilities
Contaminated Packaging: Rinse thoroughly or triple rinse, treat rinsate as hazardous, dispose packaging as hazardous waste
Pollution Prevention: Reduce chemical waste through careful inventory management, use lower volumes where possible, implement spill control measures
UN Number: Not classified as a dangerous good by most transport regulations
UN Proper Shipping Name: Not regulated for transport (verify locally in case guidelines change or for bulk shipments)
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Marine Pollutant: May threaten aquatic environments if spilled, prevent release during transport
Special Precautions: Package securely, mark as hazardous chemical for lab use, transport in accordance with all applicable regulations, avoid extreme temperature and mechanical shock
Labeling: Labels should follow OSHA HCS, GHS, or other relevant standards for laboratory chemicals
US TSCA Status: Component listed or covered
EU REACH Status: Not registered as a high production volume substance, may not require REACH registration for research uses
Other Regulations: Subject to workplace controls for hazardous chemicals, environmental protection acts, and safe chemical use guidelines
Worker Protection: Use follows occupational health and safety guidance for chemical hazards
California Prop 65: Not listed for carcinogenic or reproductive toxicity
Country-Specific Guidance: Comply with local chemical safety, labeling rules, and disposal protocols in all places of use
