Product Name: N-Propyl-N-Methylpiperidinium Bromide
Chemical Family: Quaternary Ammonium Compound
Synonyms: 1-Methyl-1-propylpiperidinium bromide
CAS Number: 3791-27-9
Recommended Use: Research and industrial chemical applications
Supplier: [Provide manufacturer information per supply chain]
Emergency Contact: [Local country emergency telephone number or poison control center]
GHS Classification: Acute Toxicity (Oral) - Category 4; Skin Irritation - Category 2; Eye Irritation - Category 2A
Label Elements:
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Precautionary Statements: Avoid breathing dust or vapors; Wear protective gloves, clothing, and eye protection; If swallowed, rinse mouth and call a poison center; Wash hands thoroughly after handling
Other Hazards: Not considered a flammable solid but may decompose under intense heat, releasing toxic bromine compounds
Potential Health Effects: Skin, eye, and respiratory tract irritation; may cause gastrointestinal discomfort, headache, nausea after ingestion
Chemical Name: N-Propyl-N-Methylpiperidinium Bromide
Molecular Formula: C9H20BrN
Molecular Weight: 238.17 g/mol
Concentration: 98% or greater (by purity)
Impurities: Water (<1%), organic by-products (<0.5%) based on standard manufacturing
Hazardous Components: None present above hazard thresholds other than the main substance
Inhalation: Move affected person to fresh air; keep comfortable for breathing; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash skin thoroughly with soap and water; seek medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for at least fifteen minutes, lifting eyelids; seek prompt medical help
Ingestion: Do not induce vomiting; rinse mouth with water; drink water if alert; get immediate medical attention
Most Important Symptoms: Itching, redness, tearing of eyes, sore throat, gastrointestinal upset
Medical Attention and Special Treatment: Symptomatic treatment only; provide respiratory support if needed
Suitable Extinguishing Media: Water fog, dry chemical powder, carbon dioxide, foam
Unsuitable Media: Direct water jet may spread chemical
Specific Hazards: Thermal decomposition creates toxic and corrosive gases such as hydrogen bromide, nitrogen oxides
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus
Advice for Firefighters: Cool exposed containers with water spray; avoid inhaling combustion gases
Further Information: Evacuate area and contain runoff to prevent release into waterways
Personal Precautions: Wear suitable protective clothing, gloves, safety goggles, and use respiratory protection if dust forms
Environmental Precautions: Prevent contamination of soil, drains, surface, and groundwater
Containment and Cleaning Methods: Sweep up cautiously to avoid dust; place in properly labeled chemical waste container; ventilate the area
Disposal of Spills: Dispose in accordance with national and local environmental regulations
Prevention of Secondary Hazards: Avoid contact with incompatible substances; clean surfaces thoroughly
Safe Handling: Use only in well-ventilated areas; avoid inhalation and contact with skin, eyes, and clothing; do not eat, drink, or smoke during use
Storage Conditions: Store in tightly closed container in a cool, dry, and well-ventilated place, out of direct sunlight
Incompatibilities: Strong oxidants, strong acids and bases, halogenated reagents
Specific Uses: Research, chemical synthesis, material development as indicated by end user
Hygiene Measures: Always practice thorough handwashing after handling
Storage Class: Corrosive or toxic, according to local classification schemes
Engineering Controls: Use chemical fume hood or adequate local exhaust; maintain eye wash stations and safety showers near work area
Personal Protective Equipment: Safety goggles, gloves (nitrile recommended), laboratory coat, and in cases of risk, a respirator with particulate filter
Exposure Limits: No established occupational exposure limits for this compound
Monitoring: Regular workplace air measurement if dust or aerosols could form
General Safety Measures: Remove contaminated clothing; avoid direct contact with eyes, skin, and mucous membranes
Appearance: White to off-white crystalline powder
Odor: Faint, amine-like
Odor Threshold: Not established
pH: 6.0 – 7.0 (1% aqueous solution)
Melting Point/Freezing Point: 153–156°C
Boiling Point: Decomposes before boiling
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Non-flammable solid
Vapor Pressure: Negligible at 20°C
Vapor Density: Not applicable
Solubility: Readily soluble in water, ethanol; limited solubility in non-polar solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Above 180°C
Viscosity: Not relevant (solid form)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Does not react under normal laboratory or industrial use
Conditions to Avoid: High temperatures, moisture, direct sunlight, incompatible substances
Incompatible Materials: Strong acids or bases, strong oxidizing agents, halogen compounds
Hazardous Decomposition Products: Hydrogen bromide, nitrogen oxides, carbon monoxide, small organic fragments at high temperature
Possibility of Hazardous Reactions: Not known under recommended use conditions
Likely Routes of Exposure: Skin and eye contact, inhalation, accidental ingestion
Acute Toxicity: Oral LD50 (rat) estimated between 300–2000 mg/kg; irritation to mucous membranes expected
Skin Corrosion/Irritation: Moderate irritant based on structure and data for similar materials
Serious Eye Damage/Irritation: Causes strong irritation and could result in reversible damage
Respiratory or Skin Sensitization: Not classified as a sensitizer but irritation may occur
Germ Cell Mutagenicity: No clear evidence from available data
Carcinogenicity: Not considered carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No known adverse effects in animal studies or available literature
Specific Target Organ Toxicity: No specific organ outlined but overexposure may cause temporary symptoms
Aspiration Hazard: Not classified as a risk
Long-term Effects: Repeated or prolonged contact may amplify irritation or allergic responses in individuals with sensitivities
Toxicity to Aquatic Organisms: May be harmful to aquatic invertebrates based on structure-activity modeling and available analog data
Persistence and Degradability: Moderate persistence in water and soil; hydrolyzes slowly
Bioaccumulative Potential: Low; compound is hydrophilic and not likely to accumulate in tissues
Mobility in Soil: Expected to have high mobility; may reach groundwater if improperly disposed
Other Adverse Effects: No ozone depletion or greenhouse gas potential identified
Ecotoxicological Assessments: Seek further information from updated registries and peer-reviewed data for environmental release scenarios
Waste Disposal Methods: Dispose of this chemical as hazardous waste by incineration in compliance with local and national regulations
Contaminated Packaging: Rinse containers and dispose like the product itself; triple rinse recommended
Sewage Disposal: Do not discharge into drains, waterways, or soil
Disposal Recommendations: Work with licensed chemical waste contractor; retain documentation
Recycling and Recovery: Not suited for recycling due to toxicity and lack of robust reprocessing infrastructure
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains N-Propyl-N-Methylpiperidinium Bromide)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: No
Special Precautions: Ensure packaging is sealed, labeled, and secured before transit; keep away from incompatible and food substances
Transport Labeling: Appropriate GHS and UN transport hazard labels
Labeling Requirements: Comply with all GHS label mandates for chemical hazards
Inventory Listings: Reference to major regulatory bodies (U.S. TSCA, EU EINECS/REACH, Canada DSL/NDSL, Australia AICS) may vary per vendor and import country
Specific Regulations: Product use restricted to laboratory, research, and industrial purposes; not for use in food, drugs, or cosmetics
Safety, Health, and Environmental Regulations/Legislation: Classified as hazardous for chemical safety and environmental release awareness
Chemical Safety Assessment: Performed and available upon request from supplier under REACH or equivalent national programs
