Material Safety Data Sheet: N-Propylpyridinium Chloride

Identification

Chemical Name: N-Propylpyridinium Chloride
Synonyms: 1-Propylpyridinium Chloride
CAS Number: 63817-57-6
Recommended Use: Chemical synthesis, research, specialty solvent
Manufacturer: Specify supplier details
Emergency Contact: Reach out to local poison control or manufacturer’s emergency line

Hazard Identification

Classification: Skin irritant, eye irritant, potentially harmful if swallowed, may cause respiratory discomfort
Label Elements: Exclamation mark pictogram, signal word "Warning"
Hazard Statements: Causes skin and eye irritation, may induce respiratory irritation, harmful if ingested
Precautionary Statements: Use gloves, eye protection, adequate ventilation, avoid release to environment
Symptoms: Redness, itching, watery eyes, coughing, nausea

Composition / Information on Ingredients

Chemical Identity: N-Propylpyridinium Chloride
Concentration: 98% or higher
Impurities: Water (<1%), unreacted pyridine (<0.5%), residual solvents (<0.2%)
Molecular Formula: C8H12ClN
Molecular Weight: 157.64 g/mol

First Aid Measures

General Advice: Remove contaminated clothing, move away from exposure
Inhalation: Move to fresh air, seek medical attention if discomfort persists, monitor respiration
Skin Contact: Rinse skin with soap and water for 15 minutes, consult a doctor if irritation continues
Eye Contact: Rinse immediately under running water for at least 15 minutes, remove contact lenses, seek medical advice
Ingestion: Rinse mouth, do not induce vomiting, call a poison control center or physician immediately

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Unsuitable Media: High pressure water jet
Specific Hazards: Decomposition may release toxic fumes (hydrogen chloride, nitrogen oxides, carbon monoxide)
Protective Equipment: Wear full protective gear and self-contained breathing apparatus
Firefighting Instructions: Stay upwind, prevent runoff to drains, cool containers with water spray

Accidental Release Measures

Personal Precautions: Put on gloves, goggles, avoid breathing dust or vapors, ventilate area
Environmental Precautions: Prevent spills from entering waterways, soil, or drains
Methods for Cleaning Up: Sweep up solid, collect into containers for disposal, wash area with plenty of water, ventilate
Disposal: Dispose of through a licensed waste contractor, follow all local and national regulations

Handling and Storage

Handling: Always use in a well-ventilated area, keep container tightly closed, avoid inhalation, ingestion, and contact with skin and eyes, employ engineering controls or fume hoods
Storage: Store in a cool, dry, well-ventilated place away from incompatible substances such as strong oxidizers, acids, or bases, keep containers tightly sealed, segregate from food and beverages, label storage area clearly

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood, local exhaust ventilation, avoid aerosol generation
Eye Protection: Wear chemical safety goggles
Skin Protection: Wear gloves made of nitrile or neoprene, wear lab coats or protective clothing
Respiratory Protection: Use air-purifying mask with organic vapor cartridge if ventilation is inadequate
Work Hygiene: Wash hands and affected skin after handling, prohibit eating, drinking, or smoking in working area

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Slightly aromatic or amine-like
Melting Point: 180-190 °C
Boiling Point: Decomposes without boiling
Solubility: Soluble in water, alcohols
Density: 1.14 g/cm³
pH: 6-7 (1% in water)
Vapor Pressure: Not measurable at room temperature
Flash Point: Not applicable
Partition Coefficient (log Kow): Not determined
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable at room temperature under recommended storage
Conditions to Avoid: High humidity, temperatures above 60°C, strong sunlight
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition: May emit hydrogen chloride, pyridine vapors, nitrogen oxides under combustion or extreme heat
Polymerization: Not known to occur

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 (rat, oral) not fully established, estimated moderate toxicity
Skin Irritation: Causes mild to moderate irritation, risk of redness and dryness
Eye Irritation: May cause pain, redness, watering, possible injury
Respiratory Effects: Short-term exposure can produce coughing, sore throat, and in some cases, upper airway irritation
Long-term Exposure: Data limited, no evidence for chronic toxicity but precaution is warranted
Sensitization: No known sensitization effects from available literature

Ecological Information

Aquatic Toxicity: Believed to be harmful to aquatic life based on similar compounds, avoid discharge to natural waters
Persistence/Degradability: May not biodegrade quickly, potential for accumulation
Bioaccumulative Potential: No established data, caution warranted
Mobility in Soil: Moderately mobile in aqueous environments
Other Adverse Effects: Precautions should prevent product from entering water courses and soil

Disposal Considerations

Recommended Disposal: Dispose through licensed chemical waste contractor, ensure collection containers are clearly marked, rinse residues thoroughly
Contaminated Packaging: Triple rinse, send to approved recycler or incinerator
Special Instructions: Never dispose of via sewage, open drains, or unauthorized landfills

Transport Information

UN Number: Not classified under UN Dangerous Goods
Transport Hazard Class: Not regulated as hazardous for transport under IATA, IMDG, or ADR
Packing Group: Not assigned
Environmental Hazards: Avoid spillage during transport, notify authorities in case of large spills
Proper Shipping Name: N-Propylpyridinium Chloride or chemical, N.O.S. if required by national law
Special Precautions: Keep containers upright, secure against movement, carry spill cleanup material in transport vehicle

Regulatory Information

Safety, Health, and Environmental Regulations: Not classified as a major hazard under US OSHA Hazard Communication, EU CLP, or GHS, but local regulations may require specific labeling
REACH Status: Not registered in EU REACH database
TSCA Status: Use in US laboratories may be exempt under research provisions, consult EPA guidance
Additional Local Information: Regulatory status and restrictions may differ in non-US/EU countries, always review applicable national law
Inventory Listings: Not included in multiple chemical inventories, approval may be needed for industrial use