Product Name: Tetrabutylphosphonium Trifluoroacetate
Chemical Formula: C17H36F3O2P
Synonyms: TBP-TFA, Tetrabutylphosphonium trifluoroacetate ionic liquid
Company Information: Manufacturer details, emergency contact number, and address listed on the original label
Recommended Use: Laboratory chemical, chemical synthesis, industrial processes
Restrictions on Use: Not for food, drug, or household applications
GHS Classification: Eye irritation (Category 2), Skin irritation (Category 2), Acute Oral Toxicity (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, serious eye irritation, harmful if swallowed
Pictograms: Exclamation mark
Precautionary Statements: Avoid contact with skin and eyes, do not eat or drink while handling, wash skin thoroughly
Other Hazards: May cause respiratory tract irritation; environmental hazard for aquatic life
Chemical Identity: Tetrabutylphosphonium Trifluoroacetate
CAS Number: 31643-50-8
EC Number: 250-860-1
Impurities: Trace organic or inorganic contaminants (normally below 1%)
Concentration: 100% pure unless specified by supplier data sheet
Other Ingredients: No stabilizers, solvents, or additives listed
Skin Contact: Remove contaminated clothing, wash affected area with plenty of water and mild soap; seek medical advice if irritation persists
Eye Contact: Hold eyelids open and rinse under gentle running water for several minutes; prioritize immediate medical attention if pain or vision changes arise
Ingestion: Rinse mouth, avoid forced vomiting, consult a physician or poison center without delay
Inhalation: Move to fresh air, keep comfortable for breathing, seek medical attention if you feel unwell or have symptoms
Notes to Physician: Treat symptomatically; monitor for delayed effects, especially gastric or pulmonary irritation
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Media: Direct water jet if risk of chemical spillage increases
Specific Hazards: Vapors may form toxic or corrosive decomposition products, including carbon oxides, phosphorus oxides, hydrogen fluoride, perfluorinated organic compounds
Special Protective Equipment: Full-body chemical-resistant suit, positive pressure self-contained breathing apparatus
Firefighting Procedures: Cool containers exposed to fire with water mist, avoid inhalation of gases, evacuate area
Personal Precautions: Wear full PPE including gloves, goggles, chemical-resistant clothing
Environmental Precautions: Prevent from entering drains, soil, or watercourses
Methods for Containment: Stop leak at source ensuring personal safety, use non-combustible absorbent (sand, earth, vermiculite)
Clean-Up Procedures: Collect residue with spark-proof tools, store in labeled containers for disposal, clean floors thoroughly with water and detergent
Decontamination: Wash surface until visibly clean, allow ventilation to disperse vapors
Handling: Operate under chemical fume hood, keep away from open ignition sources, eat or drink prohibited in work area, limit physical handling with gloves and tools
Storage Conditions: Store tightly closed in original container, cool, dry, and well-ventilated area, away from heat and sunlight, segregate from strong oxidizers, acids, and bases
Storage Incompatibilities: Incompatible with strong alkalis, strong oxidizing agents, hydrolyzing agents
Container Requirements: Use compatible material (HDPE, glass); avoid metal containers if possible
Safe Transfer Advice: Use static discharge protection and grounded containers
Control Parameters: No specific occupational exposure limits available for this compound; rely on general chemical workplace standards
Engineering Controls: Local exhaust ventilation, chemical fume hood, eye wash station, emergency shower
Personal Protective Equipment: Safety goggles with side shields, face shields as required, nitrile or neoprene gloves, full body protective clothing, properly fitted respirator for vapor or aerosol risk
Hygiene Measures: Remove contaminated clothing immediately, respond to any spills right away, always wash hands before meals and after handling
Environmental Exposure: Keep process enclosures intact, control vapor and dust by using all possible containment strategies
Appearance: Clear or slightly yellowish liquid
Odor: Faint sweet or organic odor
Odor Threshold: Not established
pH: Not determined
Melting/Freezing Point: Typically below room temperature
Boiling Range: Not precisely established
Flash Point: Expected to be above ambient temperature; handle as combustible
Evaporation Rate: Not measured
Flammability: Not classified as highly flammable, but vapors may ignite under heat or spark
Vapor Pressure: Negligible under ambient conditions
Relative Density: About 1.1 – 1.3 g/cm³ at 25 °C
Solubility in Water: Moderately soluble
Partition Coefficient (n-octanol/water): Not measured
Auto-Ignition Temperature: Unknown
Decomposition Temperature: Breaks down above 200 °C
Viscosity: Moderate to high, depends on specific lot and purity
Chemical Stability: Chemically stable under recommended storage and usage; avoid unprotected exposure to moist air over long periods
Reactivity: May react vigorously with strong oxidizers, strong acids, or alkalis; avoid contact
Hazardous Decomposition: Can generate toxic gases (phosphorus oxides, hydrogen fluoride, carbon monoxide, carbon dioxide) at high heat or open flame
Polymerization: Does not polymerize under normal conditions
Incompatible Materials: Acid chlorides, acid anhydrides, ammonia, oxidizing substances, alkali metals
Conditions to Avoid: Avoid elevated temperatures, direct sunlight, moisture, and storage near reactive chemicals
Routes of Exposure: Ingestion, inhalation, skin splash, eye contact
Acute Health Effects: May cause burning or irritation on skin and eyes, nausea, vomiting, abdominal pain if swallowed, respiratory distress if inhaled
Chronic Health Effects: Repeated exposure could lead to dermatitis, lung irritation, possible liver or kidney stress (based on class similarities)
LD50 (Oral, Rat): Not publicly reported, comparable quaternary phosphonium compounds LD50 ranges 300-2000 mg/kg
LD50 (Dermal, Rabbit): Not available
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No relevant data available
Reproductive Effects: No known risks documented; avoid exposure during pregnancy as best practice
Sensitization: May cause delayed skin or respiratory sensitivity in susceptible individuals
Aquatic Toxicity: Toxic to aquatic life, both acute and chronic exposure may cause harm to invertebrates and fish based on structural analogs
Soil Mobility: Mobile in soil, risk of leaching to groundwater where not properly contained
Persistence and Degradability: Degradation in environment may be slow; breakdown products can be persistent
Bioaccumulation Potential: May accumulate in aquatic organisms depending on exposure and molecular stability
Other Effects: Risk of long-term adverse effects in aquatic settings
Waste Disposal Method: Dispose as hazardous chemical waste in accordance with local, regional, and national regulations
Container Disposal: Rinse container with suitable solvent, collect rinsate for hazardous-waste disposal
Incineration: Only in chemical incinerator equipped with afterburner and scrubber
Sewer Disposal: Prohibited
Recommended Practices: Label waste clearly, consult licensed waste contractor, and maintain records of all disposals
UN Number: Not assigned under UN Orange Book
Shipping Name: Not classified as dangerous good under ADR, IMDG, or IATA for air, sea, and road transport if handled in small laboratory amounts
Transport Hazard Class: Not regulated, treat as hazardous in case of larger volumes
Packing Group: Not formally classified
Marine Pollutant: Potential hazard due to aquatic toxicity
Precautions for Transport: Keep sealed, upright, and insulated from direct sunlight or water contact; use secondary containment for bulk shipments
Classification: Classified under chemical legislation (REACH, OSHA Hazard Communication Standard)
Inventory Status: Listed in relevant chemical inventories (TSCA, EINECS/ELINCS, AICS where imported)
Labeling Requirements: GHS-compliant hazard pictograms, signal word, and hazard/precautionary statements
SARA Title III (USA): Not listed as an Extremely Hazardous Substance
California Proposition 65: No known listed chemicals
Workplace Regulations: Comply with occupational health and safety provisions for hazardous chemicals
Other Local Requirements: Check country-specific regulations for chemical handling, storage, transport, and disposal
