Product Name: Tetrabutylphosphonium Trifluoromethanesulfonate
Chemical Formula: C16H36F3O3PS
CAS Number: 56610-81-2
Synonyms: TBP-TfO, Phosphonium triflate
Recommended Use: Ionic liquid, phase transfer catalyst, chemical synthesis
Supplier: Contact chemical supplier or laboratory distributor
Emergency Contact Number: Refer to local regulations or manufacturer’s emergency line
Classification: Harmful if swallowed, causes skin and eye irritation, suspected of damaging fertility, may cause respiratory irritation
Hazard Statements: H302: Harmful if swallowed; H315: Causes skin irritation; H319: Causes serious eye irritation; H335: May cause respiratory irritation
Precautionary Statements: Avoid breathing dust or vapor, wash hands thoroughly, do not eat or drink during use, wear protective gloves and eye protection
Pictograms: Exclamation mark, health hazard
Signal Word: Warning
Substance: Tetrabutylphosphonium trifluoromethanesulfonate
Chemical Identity: C16H36F3O3PS
Purity: More than 95%
Impurities: Typical levels below 1% (consult specific supplier batch analysis)
Other Components: No significant hazardous impurities present in levels above regulatory reporting thresholds
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, seek medical advice if irritation continues
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, consult a physician if symptoms persist
Inhalation: Move to fresh air, keep person comfortable and at rest, seek medical attention if any symptoms develop
Ingestion: Rinse mouth, do not induce vomiting, get immediate medical attention
Most Important Symptoms: Burning sensation, redness, itching, nausea, cough
General Advice: Avoid contact with skin, eyes and clothing; use in well-ventilated environment
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Unsuitable Extinguishing Media: Direct water jets may spread fire
Special Hazards: Combustion releases carbon oxides, phosphorus oxides, sulfur oxides, hydrogen fluoride, toxic fumes
Advice for Firefighters: Use full protective clothing, self-contained breathing apparatus
Specific Methods: Cool containers exposed to fire with water spray to prevent pressure buildup
Explosion Hazards: No known unusual fire or explosion hazard for pure substance under normal conditions
Personal Precautions: Evacuate area, avoid breathing vapors, ensure adequate ventilation, use personal protective equipment including gloves and goggles
Environmental Precautions: Prevent spill from entering drains, surface water, or groundwater
Methods for Containment: Absorb with inert material (sand, earth), place in chemical waste container
Clean-up Procedures: Use non-sparking tools, avoid creating dust, wash contaminated area with plenty of water after pick-up is complete
Handling: Use in well-ventilated areas, keep containers tightly closed, avoid contact with skin and eyes, wear appropriate PPE
Storage: Store in cool, dry, well-ventilated location, keep away from incompatible substances such as strong oxidizers, acids and bases; protect from moisture
Special Requirements: Container materials must be compatible to prevent corrosion and leaks
Transfer Precautions: Use inert atmosphere if possible during transfer and dispensing, ground all equipment to prevent static discharge
Exposure Limits: No occupational exposure limits established by OSHA, ACGIH, NIOSH, or EU
Engineering Controls: Local exhaust ventilation, safety showers, eye wash stations
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile, neoprene), protective safety glasses or goggles, lab coat or chemical-resistant apron, proper respiratory protection in case of inadequate ventilation
Hygiene Measures: Wash hands after handling, do not eat or drink in work area, remove contaminated clothing promptly
Appearance: Colorless to pale yellow liquid or crystalline solid
Odor: Mild, characteristic
pH: Not applicable (non-aqueous)
Melting Point: 35 – 42°C
Boiling Point: Decomposes before boiling
Flash Point: Above 150°C (closed cup, estimated)
Evaporation Rate: Not available
Solubility: Miscible with many organic solvents, low solubility in water
Vapor Pressure: Very low at ambient conditions
Density: Around 1.1 – 1.2 g/cm³ at 20°C
Partition Coefficient (log Kow): Not readily available
Vapor Density: Not determined
Autoignition Temperature: No data
Decomposition Temperature: >150°C
Viscosity: 50 – 200 cP at 25°C (typical value)
Chemical Stability: Stable under normal conditions of use and storage, sensitive to heat above decomposition temperature
Conditions to Avoid: Excessive heat, open flames, strong oxidizing conditions
Incompatible Materials: Strong oxidizers, strong acids, bases, water (hydrolysis may occur over time), some metals
Hazardous Decomposition Products: Carbon oxides, phosphorus oxides, sulfur oxides, hydrogen fluoride, organophosphorus compounds
Polymerization: No dangerous polymerization foreseen under normal handling
Acute Toxicity: Oral LD50 (rat) above 2000 mg/kg (based on structural analogues), inhalation data not available
Skin Corrosion/Irritation: May cause moderate skin irritation
Serious Eye Damage/Irritation: Can cause serious eye irritation
Respiratory Sensitization: Prolonged inhalation may lead to respiratory tract irritation
Skin Sensitization: No data on sensitization, not reported for structurally similar compounds
Germ Cell Mutagenicity: No data available, no mutagenic effects expected for this structure
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: Some phosphonium salts have shown potential effects on fertility in animal studies, use with care
STOT – Single Exposure: May cause respiratory irritation
STOT – Repeated Exposure: No significant organ toxicity noted for related phosphonium salts
Aspiration Hazard: Low vapor pressure suggests low aspiration risk
Ecotoxicity: Limited data, similar compounds show low to moderate toxicity to aquatic organisms, avoid release to environment
Persistence and Degradability: Likely to be persistent, high chemical stability, slow degradation in environment
Bioaccumulative Potential: Potential for bioaccumulation judged to be low due to ionic nature and water solubility
Mobility in Soil: Expected to have moderate mobility in soil, but can bind to organic matter
Other Adverse Effects: No data available on ozone depletion, global warming, or photochemical ozone creation potential
Waste Treatment Methods: Dispose of content and container to hazardous or special waste collection point, do not dump into drains or environment
Contaminated Packaging: Clean container before reuse or offer for professional disposal
Recommendation: Consult local, regional, and national regulations for chemical waste disposal, incineration under controlled conditions preferred
Special Precautions: Prevent releases during handling and disposal
UN Number: Not assigned
UN Proper Shipping Name: Not regulated as hazardous for transport under ADR/RID, IMDG, or IATA
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not considered marine pollutant
Special Precautions: Use protective packaging to prevent leaks or spills during transport, keep container tightly closed
EU Regulations: Not classified as hazardous under Regulation (EC) No 1272/2008 (CLP), REACH exemption may apply for research and development
US Regulations: Not listed on the TSCA inventory, for research and development use only
Canada: Not listed on DSL/NDSL inventory
Japan: Not listed in ENCS
China: Not listed on IECSC
Other Regulations: Observe all national and local regulations relating to chemical substances
Labelling Requirements: Hazard pictograms, safety instructions needed in workplace as per local jurisdictions
