Product Name: Tetramethylguanidine Tetrafluoroborate
Chemical Formula: C5H13N3·BF4
CAS Number: 13647-34-4
Synonyms: N,N,N’,N’-Tetramethylguanidine Tetrafluoroborate
Recommended Use: Organic synthesis, catalyst, laboratory reagent
Manufacturer/Supplier: Contact laboratory supplier or chemical manufacturer for details
Emergency Contact: Refer to supplier information and local emergency numbers
Classification (GHS): Acute Toxicity Category 3 (oral, dermal, inhalation), Skin Irritant Category 2, Eye Irritant Category 2A, Specific Target Organ Toxicity (Single Exposure) Category 3, Corrosive to Metals Category 1
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin or inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Reacts with metals to release flammable hydrogen gas.
Pictograms: Skull and crossbones, Exclamation mark, Corrosion
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves and eye/face protection, wash thoroughly after handling, use only outdoors or in well-ventilated area, do not eat, drink or smoke when using, store locked up, dispose of container according to regulations
Chemical Name: Tetramethylguanidine Tetrafluoroborate
Chemical Formula: C5H13N3·BF4
Concentration: Approximately 97–99%
Impurities: Trace water, residual solvents, unidentified organic compounds at low ppm levels, not classified as hazardous according to supplier specification
Inhalation: Remove person to fresh air, keep at rest, seek immediate medical attention. Oxygen may be needed if breathing stops.
Skin Contact: Remove contaminated clothing, wash affected area with soap and water for minimum 15 minutes. Seek medical advice if irritation persists.
Eye Contact: Rinse affected eye(s) with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Remove contact lenses if present. Get immediate medical attention.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Offer water to drink if conscious. Contact poison center or physician immediately.
Extinguishing Media: Dry powder, carbon dioxide, foam. Avoid water streams which may spread the substance.
Hazards from Combustion: Releases toxic gases including fluorine compounds, boron oxides, nitrogen oxides, cyanide when decomposed by fire.
Protective Equipment for Firefighters: Full protective clothing, self-contained breathing apparatus required.
Specific Hazards: Dusts may form explosive mixtures with air. Reactivity toward metals can generate flammable hydrogen gas. Avoid inhalation of smoke or fumes.
Personal Precautions: Wear chemical-resistant gloves, safety goggles, protective suit, and suitable respirator if risk of inhalation occurs.
Environmental Precautions: Prevent release into drains, waterways, or soil. Prevent spread of dust.
Methods for Clean Up: Collect spilled solid in sealable containers using non-sparking tools. Ventilate area. Wash affected area thoroughly with water after material removal. Dispose as hazardous waste. Decontaminate equipment after handling.
Precautions for Safe Handling: Avoid contact with skin, eyes, and clothing. Wash hands and face before breaks and after use. Use only in fume hood or ventilated area. Keep containers tightly closed when not in use. Prevent dust generation and accumulation.
Conditions for Safe Storage: Store in a cool, dry, well-ventilated location, separate from incompatible substances (metals, bases, water, acids). Use corrosion-resistant containers. Keep away from food and drink. Store under inert atmosphere if possible to limit moisture uptake. Label containers clearly.
Control Parameters: No established specific workplace exposure limits. Monitor atmospheric levels for potential fumes and dusts.
Engineering Controls: Use fume hood or localized exhaust ventilation. Wash contaminated clothing before reuse.
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles, face shield, laboratory coat or apron, long pants, closed shoes. Use full-face respirator with organic vapor/acid gas cartridge in case air concentrations exceed safe levels.
Hygiene Measures: Do not eat, drink, or smoke during handling. Wash hands thoroughly.
Appearance: White to off-white crystalline powder
Odor: Amine-like
Melting Point: Approx. 110–115°C
Boiling Point: Not applicable (decomposes prior to boiling)
Solubility: Soluble in water, alcohols, DMF, DMSO
Density: Approx. 1.30 g/cm3
pH: Generates alkaline solutions in water
Vapor Pressure: Not constant (low if any)
Flash Point: Not flammable, but dust can pose explosion hazard
Autoignition Temperature: Data not available
Partition Coefficient (n-octanol/water): No data
Chemical Stability: Stable under recommended storage conditions, but slowly hydrolyzes in presence of moisture.
Conditions to Avoid: Exposure to strong oxidizers, strong acids, bases, moisture, elevated temperatures.
Incompatible Materials: Strong acids, strong bases, reactive metals (aluminum, zinc), oxidizing agents, water.
Hazardous Decomposition Products: Hydrogen fluoride, tetrafluoroborate species, boron compounds, nitrogen oxides, carbon dioxide, cyanides when burned.
Possibility of Hazardous Reactions: Liberates highly toxic and corrosive gases if mixed with acids or upon thermal decomposition.
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: High oral and dermal toxicity based on structurally related substances. Oral LD50 (rat): 50–200 mg/kg (estimated). Harmful or fatal if swallowed, inhaled or contacts skin.
Irritant/Corrosive Effects: Causes severe irritation to skin, eyes, and mucous membranes.
Symptoms of Overexposure: Burning sensation, headache, nausea, respiratory distress, vomiting, abdominal pain, skin blistering, vision impairment.
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, or OSHA.
Reproductive Effects: Not enough data for conclusive risk; handle with caution.
Additional Toxicological Data: Prolonged exposure may aggravate respiratory conditions. Effects may be delayed.
Ecotoxicity: Harmful to aquatic life. No measured LC50 or EC50 values, based on similar tetrafluoroborates.
Mobility in Soil: Likely to migrate through soil, persistent under most conditions.
Persistence and Degradability: Poorly biodegradable, stable in water unless hydrolyzed by acid/base
Bioaccumulation: Unlikely, based on physicochemical profile
Other Information: Avoid release to local environment. High hazard for ground and surface waters.
Disposal Methods: Treat as hazardous waste. Use licensed waste disposal contractor. Incinerate under controlled conditions. Do not discharge to sewers, waterways, or soil.
Contaminated Packaging: Rinse thoroughly, dispose of as per local regulations for hazardous materials.
Waste Codes: Refer to local/regional/national regulations for assignment of proper codes.
UN Number: Consult latest version of UN Dangerous Goods List (UN identification for organic base or corrosive solid can apply)
Proper Shipping Name: Tetrafluoroborate Organic Salt, n.o.s.
Transport Hazard Class: 6.1 (Toxic substances), secondary 8 (Corrosive)
Packing Group: II or III, depending on actual assessment
Labels Required: Toxic, Corrosive
Special Precautions for Transport: Ship in sealed, corrosion-resistant containers. Avoid contact with water during transit.
Safety, Health and Environmental Regulations: Not specially regulated under US EPA TSCA, EU REACH, or Canadian DSL. Subject to general occupational chemical handling regulations.
Risk Phrases: R25 (Toxic if swallowed), R34 (Causes burns), R37 (Irritating to respiratory system)
Safety Phrases: S26 (In case of contact with eyes, rinse immediately), S36/37/39 (Wear suitable protective clothing, gloves, eyewear), S45 (In case of accident, seek medical advice)
Other International Regulations: Follow all applicable labor and environmental safety directives
