Product Name: Tetramethylguanidine Trifluoromethanesulfonate
Synonyms: TMG Triflate
Recommended Use: Laboratory chemical, synthesis intermediate
Manufacturer: Specific manufacturer and address details found on container label
Emergency Contact: Local poison control; Manufacturer’s emergency number
CAS Number: 117024-68-9
EC Number: 603-511-1
GHS Classification: Corrosive to skin (Category 1B), seriously damaging to eyes (Category 1), may cause respiratory irritation (Category 3)
Label Elements: Danger symbol, corrosive pictogram, exclamation mark
Hazard Statements: Causes severe skin burns and eye damage, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust or mist, wash hands thoroughly after handling, wear protective gloves and eye protection
Routes of Exposure: Skin, eyes, inhalation, ingestion
Symptoms: Burning sensation, coughing, shortness of breath, severe eye pain, skin irritation
Chemical Name: Tetramethylguanidine Trifluoromethanesulfonate
Synonyms: 1,1,3,3-Tetramethylguanidine triflate
CAS Number: 117024-68-9
EC Number: 603-511-1
Purity: Greater than 97%
Any impurities: Less than 3%, identified on individual lot basis
Inhalation: If symptoms develop, move person to fresh air. Seek immediate medical attention if discomfort continues.
Skin Contact: Remove contaminated clothing, rinse skin with copious amounts of water for at least 15 minutes. Contact a physician promptly.
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if present and easy, keep rinsing, obtain immediate medical care.
Ingestion: Do not induce vomiting. Rinse mouth thoroughly. Call a poison center or physician right away.
Suitable Extinguishing Media: Dry chemical, CO2, water spray, alcohol-resistant foam
Specific Hazards: Releases toxic gases (nitrogen oxides, carbon oxides, sulfur oxides, hydrogen fluoride) under fire
Protective Equipment: Full protective gear, self-contained breathing apparatus
Advice for Firefighters: Cool containers with water spray. Prevent run-off from entering drains or waterways.
Personal Precautions: Wear chemical-resistant gloves, face shield or goggles, suitable protective clothing. Avoid breathing dust.
Environmental Precautions: Prevent product from entering drains, surface water, or soil.
Methods for Clean Up: Scoop or sweep up into a labeled chemical waste container. Clean surface with suitable detergent. Ensure adequate ventilation during clean-up.
Handling: Minimize dust generation and exposure. Handle with appropriate personal protective equipment. Never eat, drink, or smoke in area where chemical is used.
Storage: Store in tightly closed original container in a cool, dry, well-ventilated place. Keep away from incompatible materials, acids, moisture, sources of ignition. Clearly label the storage container.
Engineering Controls: Use local exhaust ventilation, chemical fume hood, or other engineering methods to control airborne exposures.
Respiratory Protection: Use a NIOSH-approved full-face respirator in areas with insufficient ventilation.
Skin Protection: Chemical-resistant gloves such as nitrile, lab coat or apron.
Eye Protection: Tight-fitting safety goggles or face shield.
Hand Protection: Gloves that meet standards for chemical protection.
Hygiene Measures: Wash hands and face thoroughly after handling, remove contaminated clothing before reuse.
Appearance: White to off-white crystalline solid
Odor: Slight, ammonia-like odor
pH: Basic in aqueous solution
Melting Point: 104-106°C
Boiling Point: Data not available (undergoes decomposition)
Flash Point: Not flammable in solid form
Solubility: Soluble in water and polar organic solvents
Partition Coefficient: Not determined
Vapor Pressure: Low at room temperature
Density: Approximately 1.35 g/cm³
Decomposition Temp: Decomposes above 200°C
Chemical Stability: Stable under normal ambient and anticipated storage and handling conditions.
Reactivity: Reacts with strong acids, strong oxidizers.
Hazardous Reactions: Can form toxic or corrosive gases on contact with acids or with moisture.
Incompatible Materials: Acids, moisture, oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen fluoride, sulfur oxides, trifluoromethanesulfonic acid
Routes of Exposure: Contact with eyes, skin, inhalation, ingestion
Acute Toxicity: Can cause burns on contact, may irritate airways if inhaled, serious eye damage.
Chronic Effects: Prolonged or repeated exposure can cause skin and eye sensitization.
Carcinogenicity: No data showing carcinogenic potential.
Mutagenicity: Not classified as mutagenic under GHS.
Reproductive Toxicity: No data indicating reproductive hazard.
Symptoms: Pain, redness, blistering, severe eye pain, corneal damage, respiratory symptoms if inhaled.
Toxicity to Aquatic Life: Product presents a hazard for aquatic organisms, can cause long-lasting harmful effects in the water environment.
Persistence and Degradability: Expected to degrade slowly in the environment.
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: High mobility if spilled, risk of contaminating water supplies.
Other Adverse Effects: Do not allow chemical to enter surface water or ground water.
Waste Treatment Methods: Dispose of in compliance with local, regional, and national regulations for hazardous chemical waste.
Methods of Disposal: Use licensed chemical waste company. Do not dump into drains, environment, or regular trash.
Packing Waste: Contaminated packaging should be treated as hazardous waste and disposed of accordingly.
UN Number: 3263
UN Proper Shipping Name: Corrosive solid, basic, organic, n.o.s. (Tetramethylguanidine Trifluoromethanesulfonate)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Marine Pollutant: Yes, may require marking
Special Precautions: Ensure containers are secure, unbroken, dry, and properly labeled
International Inventories: May require registration under local chemical regulations
OSHA Hazards: Corrosive, irritant
SARA Title III: Not regulated
TSCA Status: Check if listed under TSCA inventory
EU Regulation: CLP Regulation (EC) No 1272/2008 – classified as corrosive, harmful to aquatic environment
WHMIS Classification: E (Corrosive Material)
Other Regulations: User must ensure conformity with all country-specific and regional requirements
