Product Name: Tetraoctylammonium Bromide
Synonyms: TOAB, TOABr, Tetrakis(octyl)ammonium bromide
Chemical Formula: C32H68BrN
CAS Number: 14866-33-2
Recommended Use: Phase transfer catalyst, chemical synthesis
Supplier Information: Manufacturer details, emergency contact phone numbers, transportation emergency telephone, address of supplier
Classification: Acute toxicity (oral, dermal), skin irritation, serious eye irritation
GHS Label Elements: Pictogram: Exclamation Mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, may cause skin and eye irritation, possible respiratory irritation
Precautionary Statements: Avoid breathing dust or vapors, wash thoroughly after handling, wear protective gloves and eye protection, use only in well-ventilated areas, avoid release to environment
Chemical Name: Tetraoctylammonium Bromide
Common Name: TOAB
Concentration: 98–100%
CAS Number: 14866-33-2
Impurities and Stabilizing Additives: None reported in high purity grades
Inhalation: Remove person to fresh air; keep comfortable, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with plenty of water and soap, seek medical attention for persistent symptoms
Eye Contact: Rinse eyes carefully for several minutes with water, remove contact lenses if present and easy to do, continue rinsing, seek medical attention if irritation continues
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, seek immediate medical attention
Most Important Symptoms: Eye and skin irritation, respiratory discomfort, gastrointestinal upset if swallowed
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Specific Hazards: May form toxic fumes of hydrogen bromide, nitrogen oxides, carbon oxides under fire conditions
Precautions for Firefighters: Wear self-contained breathing apparatus, full protective gear, prevent contaminated firefighting water from entering drains or watercourses
Additional Information: Cool containers with water spray to prevent overheating, keep upwind, evacuate unnecessary personnel
Personal Precautions: Avoid dust generation, ensure adequate ventilation, evacuate personnel to safe areas, use personal protection equipment
Environmental Precautions: Prevent release into sewers, surface water and soil, notify authorities if large releases occur
Cleaning Methods: Sweep up spilled material without generating dust, place in suitable container for disposal, wash spill area with water after material pickup
Disposal: Dispose of contaminated materials as hazardous waste per local requirements, consult appropriate authorities
Handling: Use only in well-ventilated areas, avoid contact with eyes and skin, prevent dust formation, wash hands thoroughly after handling, use appropriate PPE
Storage: Keep in tightly closed original containment, store in cool, dry place away from incompatible materials, protect from moisture, keep away from sources of ignition
Incompatible Materials: Strong oxidizing agents, acids, moisture sensitive materials
Occupational exposure limits: No specific regulatory limit established for TOAB, keep airborne concentrations as low as possible
Engineering Controls: Use fume hood or other local exhaust system, eye wash and safety shower stations must be accessible
Personal Protective Equipment: Chemical-resistant gloves, safety goggles or face shield, lab coat, suitable respiratory protection for dust exposure, avoid skin contact
Hygiene Measures: Remove contaminated clothing, wash hands and face before breaks and end of work, do not eat, drink or smoke while handling
Appearance: White to off-white crystalline powder
Odor: Slight ammonia-like
Odor Threshold: Not established
pH: Not applicable (insoluble in water)
Melting Point: 75–80°C
Boiling Point: Decomposes before boiling
Flash Point: Not determined
Evaporation Rate: Not determined
Flammability: May be combustible at high temperature
Vapor Pressure: Negligible at standard conditions
Solubility: Insoluble in water, soluble in chloroform, benzene, acetone
Density: Approx. 1.0 g/cm³
Partition Coefficient n-octanol/water (log Kow): Not available
Decomposition Temperature: Above 150°C
Viscosity: Not relevant (solid)
Molecular Weight: 586.8 g/mol
Chemical Stability: Stable under standard conditions, avoid elevated temperatures
Conditions to Avoid: Moisture, strong oxidizers, heat sources, direct sunlight
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Hydrogen bromide, nitrogen oxides, carbon oxides
Possibility of Hazardous Reactions: Will not polymerize
Acute Toxicity: Harmful if ingested or inhaled, data shows moderate oral toxicity in rats
Skin Corrosion/Irritation: May cause irritation to skin on prolonged contact
Serious Eye Damage/Irritation: Causes eye irritation, redness and watering
Respiratory Sensitization: May cause respiratory tract discomfort or irritation on inhalation of dust
Carcinogenicity: No known components considered carcinogenic
Reproductive Toxicity: No definitive data indicating reproductive hazards
Target Organ Effects: May cause stomach pain, nausea, headache, skin dryness or cracking
LD50 (oral, rat): Estimated between 300-2000 mg/kg
Long-term Effects: No data available, avoid repeated exposures
Toxicity to Aquatic Life: Expected to be harmful to aquatic organisms; avoid environmental release
Persistence and Degradability: Limited biodegradability, persistent in environment
Bioaccumulative Potential: High potential due to hydrophobicity
Mobility in Soil: Strongly adsorbed to soil due to long hydrophobic tails, limited migration
Other Adverse Effects: Not classified as ozone depleter or hazardous air pollutant
Aquatic Ecotoxicity: Low water solubility limits immediate risk, but long chain ammonium cations pose danger to fish and invertebrates
Waste Disposal Methods: Incinerate or land-fill at approved facilities according to local, regional, and national regulations, do not release to environment
Contaminated Packaging: Dispose in the same manner as product, triple-rinse containers before offering for recycling or reuse
Special Precautions: Fully comply with hazardous waste labeling and transportation codes, consult hazardous waste authorities
UN Number: Not regulated under UN transport codes for most quantities
Proper Shipping Name: Tetraoctylammonium Bromide
Transport Hazard Class: Not classified as dangerous for shipping
Packing Group: Not applicable
Environmental Hazards: Considered hazardous for water, avoid accidental releases during transport
Special Transport Precautions: Transport in closed, labeled containers, avoid heat and moisture
Safety, Health and Environmental Regulations: No OSHA PEL or ACGIH TLV values established, TSCA listed, not regulated under SARA Title III or CERCLA, not listed as carcinogen under IARC, NTP, or OSHA
EU Regulations: REACH registration number available upon request, not classified as a substance of very high concern
Canadian Regulations: Listed on Canadian DSL/NDSL, WHMIS not classified
Other International Regulations: Consult national inventories for status in other regions
