Product Name: Tetraphenylphosphonium Chloride
Chemical Formula: C24H20PCl
CAS Number: 2001-45-8
Synonyms: Tetraphenylphosphonium Chloride, TPPC
Recommended Use: Laboratory chemicals, research and development
Manufacturer: Consult chemical supplier
Contact Number: Check supplier label
Emergency Contact: CHEMTREC (in the USA) or local emergency service
Hazard Classification: Acute oral toxicity (Category 4), Skin and eye irritation possible
Signal Word: Warning
Hazard Statements: Harmful if swallowed; may cause irritation to skin, eyes, and respiratory tract.
Precautionary Statements: Avoid breathing dust; Wash thoroughly after handling; Do not eat, drink, or smoke when using this product.
Label Elements: Exclamation mark pictogram recommended
Potential Health Effects: Irritation through contact or inhalation; abdominal discomfort after ingestion.
Environmental Hazards: Not classified as dangerous to the environment, but avoid release to waterways to prevent long-term effects.
Other Hazards: Dust formation may present explosion risk; Electrostatic charging possible
Chemical Name: Tetraphenylphosphonium Chloride
CAS Number: 2001-45-8
Concentration: >98% (pure form)
Impurities: Minimal, presence of moisture or organic solvent possible with technical grade
Additional Components: No dangerous impurities known in standard laboratory stock
Inhalation: Move exposed person to fresh air and keep comfortable; Seek medical advice if symptoms develop
Skin Contact: Remove contaminated clothing and wash skin thoroughly with soap and water; Seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing; Obtain medical help for lasting discomfort
Ingestion: Rinse mouth, do not induce vomiting; Give water to drink if conscious; Get medical attention rapidly
Most Important Symptoms: Irritation, redness, abdominal pain, headache potentially
Advice to Physicians: Symptomatic treatment, monitor respiratory and cardiovascular functions
Suitable Extinguishing Media: Dry chemical, CO2, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jet (may spread chemical)
Fire Hazards: In fire, toxic and corrosive gases such as phosphorus oxides, hydrochloric acid, and carbon oxides can form
Special Fire-fighting Procedures: Wear self-contained breathing apparatus and protective clothing; Move containers from danger if safe
Explosion Hazard: Dust can form explosive mixtures with air in confined spaces
Further Information: Cool fire-exposed container with water spray
Personal Precautions: Evacuate personnel to safe area; provide adequate ventilation; put on gloves, goggles, dust mask or respirator
Environmental Precautions: Avoid run-off into drains, soil, and waterways; Inform authorities if significant contamination leaves working area
Methods for Clean-Up: Sweep up using non-sparking tools, collect dry in a sealed container for disposal; wash area with soap and water to remove residue
Avoidance: Prevent dust formation and spread; clean in a way to minimize airborne exposure
Disposal of Debris: Place in labeled chemical waste container for appropriate disposal
Safe Handling Recommendations: Use only with local exhaust ventilation; avoid contact with skin, eyes, and clothes; prevent dust buildup
Handling Practices: Do not eat, drink, or smoke in work area; wash hands thoroughly after use
Safe Storage Practices: Store in cool, dry, well-ventilated area; keep tightly closed in original container; keep away from strong oxidizers and acids
Special Storage Needs: Store in inert atmosphere or under desiccant to avoid moisture uptake
Incompatibilities: Avoid contact with oxidizing agents, strong acids, and bases; generates heat or decomposition products
Exposure Limits: No established OSHA, NIOSH, or ACGIH exposure limits for this compound
Engineering Controls: Use chemical fume hood or other local exhaust; avoid release of dust to workplace air
Personal Protective Equipment: Full-length lab coat, nitrile gloves, safety goggles, and when necessary, properly fitted dust respirator (P100 or equivalent)
Hygiene Measures: Change contaminated clothing; wash hands after handling; keep chemical away from food or drinks
Environmental Protection: Follow local chemical safety rules to trap vapors and particulates with HEPA or carbon filters if vented to outside
Appearance: White to off-white crystalline solid or powder
Odor: Odorless
Odor Threshold: Not applicable
Melting Point: 250–260°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility (Water): Soluble (forms clear solution at room temperature)
Solubility (Other): Soluble in polar organic solvents such as alcohols and acetone
Density: about 1.18 g/cm³ @ 20°C
Vapor Pressure: Not applicable (non-volatile)
Vapor Density: Not applicable
pH: 5-7 (5% aqueous solution)
Partition Coefficient: No data
Flash Point: Not flammable under standard conditions
Autoignition Temperature: No information available
Evaporation Rate: Not volatile
Viscosity: Not applicable
Chemical Stability: Stable under standard laboratory conditions for handling and storage
Thermal Decomposition: Breaks down at high temperatures, releasing toxic fumes (phenyl derivatives, phosphorus oxides, HCl)
Reactivity with Other Chemicals: Reacts vigorously with oxidizing agents and strong acids
Hazardous Reactions: Can form combustible dust-air mixtures
Conditions to Avoid: Moisture, excessive heat, incompatible chemicals
Hazardous Decomposition Products: Carbon oxides, phosphorus compounds, phenyl species, hydrogen chloride gas
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): 300–2000 mg/kg (moderate toxicity)
Chronic Toxicity: Data unavailable; repeated exposure may cause organ effects based on related compounds
Local Effects: Irritation to skin, eyes, lungs; mild burns in severe exposures
Sensitization: No sensitization data
Mutagenicity: No evidence found in standard tests
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Other Relevant Effects: Stomach pain or headache after accidental swallowing
Aquatic Toxicity: Limited data suggest low toxicity to aquatic organisms in standard tests
Persistence and Degradability: Expected to persist in soil and water; not readily biodegradable
Bioaccumulation Potential: Not significant based on chemical structure, but complete testing data missing
Mobility in Soil: Moderate mobility in water due to ionic nature
Other Adverse Effects: Environmental impact under normal laboratory use remains minor if release prevented
Precautions: Prevent contamination of surface waters, sewers, and soil
Waste Treatment Methods: Collect and store waste in sealed, labeled chemical containers for disposal by licensed chemical waste management contractor
Disposal of Packaging: Rinse chemical glassware or containers with water, add rinse to waste bottle, and dispose according to local, regional, and national regulations
Special Precautions: Do not dump waste into drains, soil, or surface water
Regulations: Follow EPA, local, and, where relevant, international guidelines for hazardous wastes
UN Number: Not regulated by UN for transportation
Proper Shipping Name: Tetraphenylphosphonium Chloride
Transport Hazard Class: Non-hazardous for air, sea, or ground transport per IATA, IMDG, and DOT
Packing Group: Not assigned
Special Transport Precautions: Keep package sealed and upright; prevent physical damage or moisture; provide documentation describing composition and hazards in shipment
Other Information: Always check with logistics provider or regional government authorities for local requirements
OSHA Hazard Communication: Meets requirements for hazardous material under OSHA Hazard Communication Standard 29 CFR 1910.1200
TSCA Inventory: Listed
RCRA Status: Waste residue or containers may be regulated as hazardous waste under RCRA
SARA Title III Sections 302/304: Not listed
SARA Title III Section 313: Not subject to reporting requirements
California Proposition 65: Not on Proposition 65 list
REACH Status (EU): Pre-registered or exempt, check supplier details
Other State or International Regulations: Apply relevant workplace hazardous substances codes; seek specific information as country/region may vary
