Product Name: Tetraphenylphosphonium Phenolate
Chemical Formula: C24H20P.C6H5O
CAS Number: 3194-31-0
Recommended Use: Laboratory reagent, organic synthesis intermediate
Supplier: Refer to the local distributor or manufacturer for detailed contact
Emergency Contact: Refer to regional poison control center or emergency services
GHS Classification: Acute Toxicity Oral (Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2A), Specific Target Organ Toxicity - Single Exposure (Category 3)
Label Elements: Exclamation mark pictogram, Signal word: Warning
Hazard Statements: Harmful if swallowed, Causes skin irritation, Causes serious eye irritation, May cause respiratory irritation
Precautionary Statements: Avoid breathing dust or vapors, Wash hands thoroughly after handling, Use only outdoors or in well-ventilated area, Wear protective gloves and eye/face protection
Potential Health Effects: Inhalation can lead to respiratory irritation, skin contact may provoke noticeable irritant effects, eye contact can cause lasting discomfort or damage, ingestion may result in symptoms similar to general poisoning
Environment Hazards: May be harmful to aquatic life, avoid release to the environment
Substance: Tetraphenylphosphonium Phenolate
Chemical Name: Tetraphenylphosphonium Phenolate
Molecular Weight: 410.50 g/mol
Purity: Typically >98%
Impurities: Trace organic and inorganic components possible from synthesis, less than 2% unless specified
Additives: No stabilizers or preservatives reported in the high-purity product
Inhalation: Move person to fresh air. Encourage deep breaths. Seek medical attention if respiratory symptoms develop.
Skin Contact: Remove contaminated clothing, rinse skin with soap and plenty of water. Medical attention required if irritation persists.
Eye Contact: Immediately flush with water for at least 15 minutes, keeping eyelids open. Obtain medical care if irritation continues.
Ingestion: Rinse mouth with water, call poison control or a physician, do not induce vomiting unless instructed by a medical professional.
Immediate Symptoms: Cough, headache, nausea, burning sensations on skin or eyes, gastrointestinal distress
Notes for Physician: Treat symptomatically. Monitor respiratory, dermal, and ocular status closely.
Extinguishing Media: Use CO2, dry chemical, foam, or water spray.
Unsuitable Extinguishing Media: High volume water jet can spread material
Hazards During Fire: Combustion can produce hazardous fumes like carbon monoxide, phosphorus oxides, and other toxic gases
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Other Precautions: Remove containers from area if safe, avoid inhaling combustion byproducts
Fire Fighting Instructions: Cool down containers with water from a safe distance to prevent pressure buildup
Personal Precautions: Wear gloves, eye/face protection, lab coat or coveralls
Environmental Precautions: Prevent spill from entering surface waters, drains, or soil
Methods for Clean Up: Sweep up spilled material using tools that minimize dust generation, place in a sealed, labeled container for proper disposal
Decontamination: Wash spill site with water and detergent after material removal, ventilate area
Emergency Procedures: Isolate area, alert relevant local authorities, follow site emergency protocols
Handling: Handle with care using appropriate protective equipment, minimize dust formation, work in a chemical fume hood or well-ventilated area
Advice for Safe Handling: Avoid contact with skin, eyes, and clothing, keep containers tightly sealed, never pipette by mouth
Storage: Store in a dry, cool, and well-ventilated location away from strong oxidizers and moisture
Storage Conditions: Keep container material compatible, such as glass or polyethylene, store away from direct sunlight and heat sources
Storage Stability: Product maintains stability under recommended conditions for at least one year
Control Parameters: No occupational exposure limits established by OSHA, ACGIH, or NIOSH for this compound
Engineering Controls: Use local exhaust ventilation or fume hood
Personal Protective Equipment: Wear nitrile gloves, chemical safety goggles, laboratory coat
Respiratory Protection: Use dust respirator if dust formation occurs
Hygiene Measures: Wash hands thoroughly after use, do not eat, drink, or smoke in the work area, remove contaminated clothing immediately
Environmental Controls: Use containment to avoid environmental escape of material, secure waste collection vessels
Physical State: Solid, appears as off-white to pale-yellow powder
Odor: Nearly odorless
pH: Not applicable (not water soluble in bulk)
Melting Point/Range: 280-285 °C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not determined for solid
Explosive Properties: No reported explosive properties
Oxidizing Properties: Not classified as an oxidizer
Vapor Pressure: Not significant
Solubility: Slight solubility in organic solvents, low solubility in water
Bulk Density: Approx. 1.2 g/cm3
Partition Coefficient (log Kow): Not experimentally available
Viscosity: Not relevant for solids
Auto-ignition Temperature: Not determined
Chemical Stability: Chemically stable under room temperatures in sealed container
Conditions to Avoid: Avoid prolonged exposure to moisture, strong light, temperatures above 40 °C
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Phosphorus oxides, carbon monoxide, carbon dioxide, potentially toxic aromatic fragments
Polymerization: No reports of hazardous polymerization under normal storage conditions
Acute Toxicity: Oral LD50 estimated (>300 mg/kg, rat), specific values subject to availability from new studies
Irritation: Causes moderate to severe skin and eye irritation, respiratory irritation possible in powder form
Corrosivity: None expected at recommended handling concentrations
Carcinogenicity: No IARC/NTP/OSHA listing for human carcinogenic potential
Mutagenicity: No data supporting mutagenic properties at standard exposure levels
Reproductive Toxicity: No data reported in laboratory tests
Long-Term Effects: Sensitization not established, ongoing monitoring recommended
Routes of Exposure: Oral, inhalation, dermal, ocular
Ecotoxicity: Harm to aquatic organisms suspected based on structural alerts for aromatic phosphonium compounds
Persistence and Degradability: Limited biodegradability expected due to aromatic and phosphonium structure
Bioaccumulative Potential: Low bioaccumulation predicted; lacks detailed bioconcentration data
Soil Mobility: Likely moderate, compound adheres to particulates and soil matrices
Other Adverse Effects: No evidence of endocrine disruption, reduce exposure to environmental receptors by using tight containment
Disposal Methods: Place in approved chemical waste container, incinerate in accordance with local, national, and international regulations
Packing Material: Use compatible, sealed containers clearly labeled as hazardous chemical waste
Disposal Precautions: Do not discharge into drains, surface water, or ground; professional chemical waste handler should be engaged
Recommended Codes: Refer to local hazardous waste catalog numbers for organic laboratory chemicals
UN Number: None assigned specifically; handle as general laboratory chemical unless regulatory update provided
UN Proper Shipping Name: Tetraphenylphosphonium Compounds - Not regulated as a hazardous material on most transport systems
Transport Hazard Class: Nonclassified
Packing Group: Usually not assigned
Environmental Hazards: Avoid spillage into water bodies or soil during transportation
Special Precautions: Package securely to avoid dust formation and prevent leaks
Transport Labels: None mandated for non-bulk, non-commercial shipments
Safety, Health, and Environmental Regulations: Compound not specifically listed by TSCA, REACH, or GHS as a restricted substance
US Regulations: Not a regulated toxic substance under SARA Section 313, CERCLA, or California Prop 65
EU Regulations: Not registered under REACH candidate list; follows general requirements for laboratory chemicals
Other International Inventories: Not specifically subject to international controls; require adherence to general chemical regulations
Worker Protection: Provide safety data training, maintain accessible safety data sheet onsite
Customs Classifications: List under laboratory chemicals, harmonized tariff schedule codes for research compounds
Standards: Adhere to OSHA laboratory safety standards, applicable regional rules, and site-specific protocols for safe workplace practices
