Substance Name: Tetrapropylammonium Hydrosulfate
Chemical Formula: C12H28N.H2SO4
CAS Number: 21041-09-2
Product Use: Used as a phase transfer catalyst and in organic synthesis
Manufacturer: Refer to specific supplier details
Emergency Contact: Local emergency response centre or Poison Control
Synonyms: TPAS, Tetrapropylammonium hydrogen sulfate
GHS Classification: Acute toxicity (Oral, Category 4), Skin corrosion/irritation (Category 2), Serious eye damage/irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Avoid breathing dust. Wash hands thoroughly after handling. Wear protective gloves, clothing, and eye protection.
Pictograms: Exclamation mark
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Chemical Name: Tetrapropylammonium Hydrosulfate
CAS Number: 21041-09-2
Concentration: 97-100%
Impurities: Negligible for most applications; check supplier specifications if pharmaceutical grade needed
Inhalation: Remove patient to fresh air as soon as discomfort develops. Seek medical attention if symptoms persist. Loosen tight clothing. Provide oxygen if breathing becomes difficult.
Skin Contact: Thoroughly wash exposed area with soap and water. Remove contaminated clothing and shoes. Consult a physician if irritation appears.
Eye Contact: Rinse eyes with copious quantities of water for at least 15 minutes while holding eyelids apart. Remove contact lenses if present and possible. Seek immediate medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention quickly, bring product label if possible.
Notes to Physician: Treat symptomatically. May produce irritation to mucous membranes or gastrointestinal tract.
Suitable Extinguishing Media: Use carbon dioxide, dry chemical or foam. Water spray is suitable for larger fires.
Unsuitable Extinguishing Media: Direct stream of water may scatter and spread fire.
Hazards: May release toxic fumes of nitrogen oxides, sulfur oxides, and ammonia under fire conditions.
Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Firefighting Instructions: Remove containers from fire area if safe. Prevent fire-fighting water from entry to waterways or drains.
Personal Precautions: Evacuate unnecessary personnel. Wear dust mask, safety goggles, gloves, and protective clothing. Avoid contact with spilled material.
Environmental Precautions: Prevent product from entering sewers, drains, surface and ground water. Inform authorities if large quantities enter environment.
Cleanup Methods: Collect spilled material with non-combustible absorbent (such as sand). Place in suitable, labeled containers. Wash spill site with water after material pickup is complete.
Disposal: Dispose of in accordance with local and national regulations.
Handling: Avoid generation of dust and inhalation of vapors or mists. Use with adequate ventilation. Use clean equipment. Do not eat, drink, or smoke in area of use.
Storage: Keep containers tightly closed in cool, dry, well-ventilated area. Store away from strong oxidizing agents, acids, and bases. Protect from moisture and direct sunlight.
Special Advice: Use only containers and packaging approved for chemical storage. Clearly label all containers.
Exposure Limits: No established exposure limits for this compound. Minimize exposure as general rule.
Engineering Controls: Use local exhaust or general ventilation.
Personal Protective Equipment: Wear chemical-resistant gloves, goggles or face shield, and lab coat. Use respiratory protection if ventilation is inadequate.
Hygiene Measures: Wash hands, forearms, and face after handling. Remove contaminated clothing before entering eating areas.
Environmental Exposure Controls: Procedures should prevent accidental release to the environment.
Appearance: White to off-white crystalline powder
Odor: Faint ammoniacal
Odor Threshold: Data not available
pH: 2-4 (5% solution in water)
Melting Point: Approximately 150 °C (decomposes)
Boiling Point: Decomposes before boiling
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability (solid, gas): Does not burn easily
Vapor Pressure: Data not available
Vapor Density: Data not available
Relative Density: Approximately 1.1 to 1.2 (water=1)
Solubility: Soluble in water
Partition Coefficient: Data not available
Auto-ignition Temperature: Data not available
Decomposition Temperature: > 150 °C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions.
Conditions to Avoid: Excessive heat, humidity, direct sunlight, incompatible substances.
Incompatible Materials: Strong oxidizers, reducing agents, strong acids, and bases.
Hazardous Decomposition Products: Ammonia, nitrogen oxides, sulfur oxides, and hydrocarbons can be released during decomposition.
Polymerization: No dangerous polymerization expected.
Acute Toxicity: May cause irritation if swallowed, inhaled, or on skin contact. Toxicity data for rodents indicate moderate oral LD50.
Skin Corrosion/Irritation: Causes irritation, may produce redness or blisters after prolonged exposure.
Serious Eye Damage/Irritation: Causes irritation with risk of corneal damage if not promptly washed away.
Respiratory Sensitization: Inhalation of dust may cause coughing, sore throat, or respiratory discomfort.
Germ Cell Mutagenicity: No data available.
Carcinogenicity: Not listed as carcinogen by IARC, ACGIH, NTP, or OSHA.
Reproductive Toxicity: No data available.
Specific Target Organ Toxicity – Single Exposure: May cause irritation to mucous membranes.
Specific Target Organ Toxicity – Repeated Exposure: No data available.
Aspiration Hazard: Not classified as aspiration hazard.
Ecotoxicity: Harmful to aquatic organisms if released in high concentrations. No chronic eco-toxicity data available.
Persistence and Degradability: Expected to degrade in the environment but at a slow rate.
Bioaccumulative Potential: No significant bioaccumulation expected.
Mobility in Soil: High water solubility means material can be mobile in soil and groundwater.
Other Adverse Effects: Avoid release to the environment. Inform appropriate authorities in case of large spills affecting water sources.
Waste Disposal: Waste should be processed in accordance with local regulations. Dilute solutions may be neutralized and discharged after consultation with authorities. Material in bulk or concentrated waste streams should be treated as hazardous waste and incinerated or landfilled at permitted sites.
Container Disposal: Containers should be drained and rinsed before disposal. Do not reuse empty packaging for other substances.
Special Instructions: Ensure incinerator is equipped with scrubbers to handle nitrogen and sulfur oxide emissions.
UN Number: Not assigned for this material under most shipping regulations
Proper Shipping Name: Tetrapropylammonium Hydrosulfate
Transport Hazard Class: Not classified as dangerous for transport, use proper containment in case of bulk transport
Packing Group: Not regulated
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Avoid transporting with incompatible chemicals such as oxidizers or acids
US TSCA: Listed in the Toxic Substances Control Act Inventory
EU REACH: Subject to registration, not on candidate list of substances of very high concern (SVHC)
SARA Title III (Sections 302/304/313): Not subject to reporting requirements
OSHA Hazard Communication Standard: Hazardous chemical
WHMIS Classification (Canada): Classified as hazardous material
Other National Regulations: Refer to local, state, or national regulations regarding labeling, handling, and usage
Chemical Safety Assessment: If product is used on an industrial scale, a chemical safety assessment may be required in certain areas
