Product Name: Trimethylamine Hydrochloride
Chemical Formula: C3H9N·HCl
Synonyms: Trimethylammonium chloride
CAS Number: 593-81-7
Recommended Uses: Used in research, chemical synthesis, and as a laboratory reagent
Manufacturer Contact: Supplier details must be checked before purchase for emergency response
Emergency Phone Number: Local poison control or chemical emergency line applies
Classification: Irritant to eyes, skin, and respiratory tract
Signal Word: Warning
Hazard Statements: Causes moderate to severe irritation to skin and eyes. Harmful if inhaled or swallowed.
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Only use in well-ventilated areas. Do not inhale dust.
Potential Health Effects: Short-term exposure can provoke nose and throat irritation, coughing, headache, and nausea. Long-term contact may increase risk for dermatitis and respiratory issues.
Environmental Hazard: Not classified under GHS as hazardous for aquatic environment but caution advised due to toxicity in larger spills
Chemical Name: Trimethylamine Hydrochloride
Concentration: 100%
CAS No.: 593-81-7
Impurities or Additives: Information supplied by manufacturer; in analytical grade, commonly not present above 0.1%
Inhalation: Remove to fresh air immediately. Seek medical attention if discomfort continues. Inhalation of dust or fumes requires observation for respiratory distress.
Skin Contact: Wash affected area thoroughly with water and mild soap. Remove contaminated clothing. See a physician if irritation develops.
Eye Contact: Rinse eyes with plenty of running water for at least 15 minutes. Seek prompt medical help if discomfort persists.
Ingestion: Rinse mouth with water, do not induce vomiting. Get medical attention promptly. Have information about the material at hand.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide.
Unsuitable Extinguishing Media: Strong water jets could spread powder.
Specific Hazards: Fumes of hydrogen chloride, nitrogen oxides, and carbon monoxide may form in a fire. Material may emit toxic fumes upon decomposition.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing.
Fire-Fighting Procedures: Move containers from fire area if safe. Cool fire-exposed containers with water. Prevent run-off from entering drains.
Personal Precautions: Wear gloves, lab coat, chemical safety goggles, and dust respirator. Ensure good ventilation.
Environmental Precautions: Prevent further leakage or spillage if safe. Avoid discharge into drains or watercourses.
Spill Clean-Up: Sweep up and place in appropriate container for disposal. Clean surfaces with water to remove trace residues.
Emergency Procedures: Restrict access to the area until clean-up is complete. Notify relevant authorities if a large spill occurs.
Handling: Use only in a chemical fume hood or well-ventilated area. Avoid creating dust. Do not get in eyes, on skin, or on clothing.
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated place away from incompatible substances, such as strong oxidizers.
Incompatibilities: Acids, strong oxidizers, and moisture can react with product.
Hygiene Recommendations: Wash hands thoroughly after handling. Remove contaminated clothing and protective equipment before entering eating areas.
Exposure Limits: Not established specifically for this compound in OSHA or ACGIH. Maintain exposure to chemicals as low as reasonably achievable.
Engineering Controls: Use fume hood and adequate exhaust ventilation to keep airborne concentrations low.
Personal Protection: Protective gloves made from nitrile, lab coat, chemical-resistant goggles, dust mask or respirator (NIOSH-approved for particulates).
Environmental Exposure Controls: Take steps to prevent entry into water and soil systems.
Appearance: White crystalline powder
Odor: Slight fishy or ammoniacal odor
Odor Threshold: No data available
pH: 5.0–6.5 (1% solution in water)
Melting Point: 225–227°C (decomposes)
Boiling Point: Not applicable
Flash Point: Not flammable
Solubility: Highly soluble in water; slightly soluble in ethanol
Relative Density: 0.92 g/cm³
Vapor Density: Not applicable
Vapor Pressure: Not applicable
Partition Coefficient (n-octanol/water): No data available
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Begins above 225°C
Evaporation Rate: Not applicable
Chemical Stability: Stable in dry, closed containers at room temperature.
Conditions to Avoid: Exposure to moisture, acids, strong oxidizers, excessive temperature.
Incompatible Materials: Strong acids, oxidizing agents, alkali metals.
Hazardous Decomposition Products: Emits toxic gases like nitrogen oxides, hydrogen chloride, and carbon monoxide during decomposition.
Hazardous Reactions: Will not occur under recommended storage and handling.
Acute Toxicity: Oral LD50 (rat): not thoroughly documented, but similar compounds show moderate toxicity.
Skin Corrosion/Irritation: Irritates skin on contact.
Serious Eye Damage/Irritation: Causes severe eye irritation.
Respiratory or Skin Sensitization: May provoke allergic respiratory or dermal response in sensitive individuals.
Germ Cell Mutagenicity: No data available
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA.
Reproductive Toxicity: No evidence from available data.
Specific Target Organ Toxicity (STOT): May cause respiratory irritation upon inhalation.
Repeated Dose Toxicity: May provoke dermatitis or upper airway irritation from prolonged exposure.
Aquatic Toxicity: Not thoroughly studied; caution recommended.
Persistence and Degradability: Expected to degrade easily in environment, but persistent spills may cause localized impact.
Bioaccumulative Potential: Expected to have low potential for bioaccumulation.
Mobility in Soil: Highly soluble; leaching possible.
Other Adverse Effects: Spills in water bodies may affect pH and aquatic life if large quantities are involved.
Product Disposal: Dispose according to local, state, and federal regulations. Incineration or landfill as hazardous waste after proper neutralization recommended.
Container Disposal: Triple-rinse and dispose of as hazardous chemical waste.
Precautions: Do not flush into surface water or sanitary sewer systems. Consult licensed waste disposal agency for proper transport and handling.
UN Number: Not regulated for transport by road, rail, air, or sea under current international regulations.
Shipping Name: Not classified as dangerous goods.
Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Prevent packaging breakage and spillage during transit.
Additional Information: Keep container tightly sealed and protected from moisture during shipment.
US Regulations: Not listed on US SARA Title III, CERCLA, or RCRA as a hazardous substance. OSHA hazard for acute toxicity.
EU Regulations: Not currently classified as a hazardous substance for environmental transport; subject to workplace safety directives.
International Inventories: Listed or exempted on most major chemical inventories.
Label Requirements: Ensure GHS-compliant pictograms and signal words on package.
Other Regulations: Consult local and national authorities for further compliance needs in handling and disposal.
