1-Dodecylimidazole: Structure, Properties, and Safe Use

What is 1-Dodecylimidazole

1-Dodecylimidazole belongs to a class of organic compounds known as imidazoles, which have a ring structure featuring two nitrogen atoms at non-adjacent positions. This specific compound attaches a dodecyl group—meaning a straight chain of 12 carbon atoms—to the imidazole ring. That long hydrocarbon tail gives it distinct physical and chemical properties not seen in simple imidazoles. The material's systematic name reveals its structure: 1-dodecyl-1H-imidazole. This compound shows up as a raw material in various chemical processes, especially in the synthesis of surfactants, corrosion inhibitors, and as an intermediate in specialty chemicals.

Molecular Formula and Structure

The molecular formula of 1-Dodecylimidazole is C15H28N2. Its structure combines the planar, aromatic imidazole ring with a long, flexible dodecyl chain, giving it amphiphilic behavior—meaning part of the molecule attracts water while the other part repels it. This feature plays a role in how the compound dissolves in various solvents. Seeing the structure in a diagram, the molecule starts with the small, five-membered imidazole ring, and the 12-carbon chain extends off one of the nitrogen sites. Each feature matters in how the molecule interacts with other materials, especially in industrial applications where solubility and surface activity count.

Physical Properties

1-Dodecylimidazole covers a surprising range in physical appearance because temperature and concentration make a difference. At room temperature, the pure compound usually turns up as a white to pale yellow solid, sometimes flaky, crystalline, or even in a powdery form. If the room gets warm enough, it can soften, and in concentrated solutions with certain solvents, it melts down into a clear or slightly turbid liquid. The density comes in close to 0.90-0.95 g/cm3—less than water, so it tends to float. The melting point falls between 26-29°C, just below the average indoor temperature, so transport and storage need attention in hot climates. The solid’s waxy feel stands out during handling, especially compared to common table salt or sugar, which are more granular. Because of the long hydrocarbon chain, it doesn’t dissolve well in water, but it mixes smoothly into organic solvents like ethanol, chloroform, acetone, or dimethyl sulfoxide (DMSO).

Specification and Purity

Most chemical suppliers offer 1-Dodecylimidazole in a purity above 97%. This attention to purity cuts down on unpredictable factors during synthesis and product formulation. Appearance and melting point can serve as rough indicators, but analytical testing—like GC analysis or NMR spectroscopy—gives a detailed assurance on the content. Impurities, especially shorter or longer chain versions, can throw off results in specialty chemical manufacturing, so experienced buyers check certificates of analysis. Properly sealed, the compound holds up well on the shelf. Still, it’s smart to keep it dry and cool, with tightly sealed lids to avoid contamination or hydrolysis.

HS Code and Trade Information

Trade in 1-Dodecylimidazole usually falls under the Harmonized System (HS) Code 2933.39, which groups heterocyclic compounds with nitrogen hetero-atoms. Customs and compliance officers use this code to standardize import and export documentation. Observing the code helps avoid logistical errors, especially since imidazoles can run into regulatory controls in some countries due to their use in specialty chemicals and coatings.

Material Forms: Flakes, Powder, Pearls, Liquid, Crystal, Solution

Depending on the production route and downstream application, 1-Dodecylimidazole can leave a supplier as waxy flakes, coarse powder, or sometimes as small pearls for easier feeding into batch processes. Bulk users lean toward solid forms—flakes or powder—since they measure and blend easily. Small laboratories often buy pre-made solutions in solvents like ethanol or methanol to save time and cut down on dust. The crystal form, if especially pure, helps check melting point and identity. At higher concentrations in certain solvents, the compound becomes syrupy; at lower concentrations, the clear solution makes for easy pipetting.

Applications and Raw Material Use

Industrial chemists dig into 1-Dodecylimidazole’s surface-active nature. Its imidazole ring introduces basicity—with a pKa of about 6.9—while the hydrocarbon tail acts like a surfactant, altering how mixtures behave on a molecular level. Specialty surfactants take advantage of these traits, and corrosion inhibitors for pipelines often draw on this chemistry to keep metal surfaces stable. Formulating products in oil and gas, textiles, and electronics often involves this compound, partly because it lowers surface tension and interacts well with both polar and non-polar substances. As a raw material, it gives rise to ionic liquids and other functionalized chemicals in research and niche manufacturing. In my own work developing specialty cleaning agents, using 1-Dodecylimidazole made for better performance as it offered both compatibility and stability in complex mixtures that relied on both water and oil-based ingredients.

Safe Handling, Hazards, and Environmental Impact

Even though 1-Dodecylimidazole looks less threatening than many industrial chemicals, it carries risks. Material Safety Data Sheets (MSDS) flag it as an irritant to skin, eyes, and the respiratory tract. Dust or vapor can provoke coughing, redness, or even chemical burns with prolonged contact. The material’s long-chain structure means it resists breakdown in water, so accidental spills put aquatic life at risk. Protective gloves, goggles, and dust masks keep workers safer, and good ventilation prevents inhalation during powder handling. Disposal of waste or spill residue follows hazardous chemical guidelines—no shortcuts with drains or open ground. If storage drums leak, secondary containment systems and absorbent materials like vermiculite help contain the hazard until proper cleanup. Chemical emergency response means more than basic first aid; trained teams recognize that even low-toxicity compounds in large amounts threaten the workplace and nearby neighborhoods.

Pushing for Better Solutions

As modern industries shift toward green chemistry, pressure grows to design safer replacements for existing surfactants and raw materials. Research teams in environmental science hover over imidazole derivatives like this one, looking for ways to make them break down more easily after use or pose less risk during accidental discharge. One practical path involves tweaking molecular design for faster biodegradation, or using encapsulation to limit release. Others have tried mixing 1-Dodecylimidazole with natural surfactants—like saponin or fatty acids from vegetable sources—to reduce the product’s overall eco-impact. In specialty manufacturing, process engineers cut exposure risks by designing closed-system reactors, automating material transfer, and choosing packaging that resists leaks. Companies that produce or use this imidazole can support transparency by sharing exact formulations, hazard data, and safe use instructions with buyers and transporters—a practice that earns trust and keeps regulators at ease.