1-Ethyl-3-Methylimidazolium Hydrogen Sulfate stands as a representative in the ionic liquid family, known in scientific circles for its low volatility and high thermal stability. Its molecular formula, C6H12N2O4S, and CAS number 409141-19-1, point straight to its distinct imidazolium cation and hydrogen sulfate anion. Industries have looked at ionic liquids like this one because early research recognized their non-flammable nature and strong solvating power, setting new performance standards for chemical synthesis, electrochemistry, and even cellulose processing.
In daily lab handling, this compound commands immediate attention: its density—commonly measured around 1.1–1.3 g/cm3—gives it a noticeable heft compared to most traditional solvents. This ionic liquid often appears as a viscous, colorless or pale yellow liquid at room temperature, though drying and cooling can yield flakes, crystalline structures, or a fine powder, depending on storage and origin. While some ionic liquids shift with humidity or minor contaminants, 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate usually maintains its integrity, making it a reliable candidate when consistent physical behavior matters. Since it dissolves a broad array of organics and inorganics, its role as a versatile reaction medium becomes apparent, especially in processes that shy away from water or conventional organic solvents.
Looking closer, the compound’s structure revolves around a five-membered imidazolium ring with ethyl and methyl groups at positions 1 and 3, coupled to a strongly associated hydrogen sulfate group. That unique assembly grants it both ionic and acidic characteristics. This duality matters when designing reactions that demand both proton transfer and ionic environments, like selective alkylations, desulfurizations, and catalytic cycles. From my own experience mixing ionic liquids with different solutes, I have found that their solvation capacity often rivals or exceeds that of classical solvents, and 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate does not disappoint on this front. Laboratories appreciate its predictable solubility profile, whether preparing solutions by the liter or dissolving raw materials at the bench scale.
Trade and safety regulations assign this chemical an HS Code—294200—which falls under organic chemical products. By global standards, customers can find it as a solid, liquid, or sometimes as pearls and crystals, with each form marketed according to application. At scale, bulk orders often arrive in high-density polyethylene drums as viscous liquid, but suppliers can offer flakes or powder for those who favor precise measurement and slower addition rates. Inside a storage cabinet, a tightly-sealed bottle prevents the ingress of atmospheric moisture, protecting purity and reactivity. Although it does not ignite as readily as typical organic solvents, a safe storage policy still treats it with sensible respect, acknowledging potential chemical hazards.
Workplace safety guides always stress respect for chemicals even if their vapor pressure sits below the threshold of concern. 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate registers as an irritant, especially to skin and eyes upon direct contact. Inhalation of dust or mist should be avoided. Material Safety Data Sheets routinely call for lab coats, chemical goggles, and gloves during use. Accidental spillage may not result in a flash fire, but prompt cleanup with suitable absorbents avoids persistent staining and reduces any risk of chemical burns. For waste disposal, following local and international guidelines ensures both personal and environmental protection. Through past experience with ionic liquids, I’ve learned the importance of adequate ventilation, especially if heating or mixing with acids and bases since small quantities of gas or heat can escape.
Raw materials feeding into the synthesis of 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate stem from readily available imidazole derivatives and sulfuric acid. Many suppliers source feedstocks from petrochemicals, though greener initiatives explore biobased imidazole frameworks. From a sustainability standpoint, chemical manufacturers confront the reality of balancing performance against potential environmental harm, studying toxicity and biodegradability with renewed focus. As interest in circular chemistry grows, ionic liquids like this face regular scrutiny about life cycle impacts, recyclability after use, and their role in greener solvent systems.
Labs and manufacturing plants see a future for 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate in advanced synthesis, catalysis, electroplating, and biomass processing. Electrochemical devices often benefit from its ionic conductivity and stability across a broad temperature range. The textile sector and pharmaceutical synthesis find its liquid state and broad solubility window useful for dissolving stubborn organics and supporting difficult reactions. Importers and academic researchers continue to evaluate product grades, prioritizing clear labeling on purity, density, and form—crystal, power, pearl, flake, or solution—for consistency from one batch to the next.
Years of chemical practice have shown me real-world supply chains and regulatory compliance depend on clear product labeling, diligent risk management, and a firm commitment to environmental responsibility. Every batch of 1-Ethyl-3-Methylimidazolium Hydrogen Sulfate brings fresh opportunities to learn about ionic liquid chemistry, innovate cleaner processes, and build a safer lab environment. Champions of green chemistry see potential in this material, but only if institutions stay honest about hazards, management protocols, and the promises and pitfalls of ionic liquid technology. Open communication, product stewardship, and strong fact-based education turn complex chemicals from unknown risks into essential tools for industry and research.
