Tetramethylguanidine Dihydrogen Phosphate brings together diverse chemical properties to create a compound that gets real work done in the lab and in industry. Built from tetramethylguanidine (C5H13N3) and phosphoric acid, this salt forms with a chemical formula of C5H15N3O4P. Its story starts in research labs innovating new catalysts, stabilizers, and specialty materials for demanding synthesis projects. You spot this material labeled under HS Code 2925.20, grouped among other organic compounds containing nitrogen. At a glance, Tetramethylguanidine Dihydrogen Phosphate makes a solid impression: its powdery or crystalline solid form tends to fall on the white to off-white side, and whether you see flakes, pearls, or microgranular crystals depends on the production technique and how it’s packed up for transport. Once measured, its density typically sits around 1.40-1.57 g/cm³, and it dissolves well in water, casting clear, transparent solutions thanks to the hydrogen phosphate group. Regular exposure to room air rarely troubles this compound – it doesn’t pull water from the air like many hygroscopic chemicals, so compounds stacked on shelves or sealed in drums tend to stay stable and ready for action.
Looking at its underlying structure, Tetramethylguanidine Dihydrogen Phosphate joins a strongly basic nitrogen base (the tetramethylguanidine group) with the acidic bite of a dihydrogen phosphate. This combination gives the compound a mild to strong alkaline characteristic, with its solution pH running closer to basic than neutral, opening the door for niche chemistry, especially organic synthesis and catalyst systems. In the solid state, each crystal is charged with opposing ions balanced out for overall neutrality. The molecular interactions involve hydrogen bonding between phosphate and guanidinium, giving the salt that extra degree of stability in both solid and dissolved forms. This structural character sets it apart from more common alkali or ammonium phosphates, handling chemical reactions with more selective reactivity, a fact that’s a big draw for chemists working on hard-to-solve synthesis puzzles.
Chemistry in the real world focuses on results and reliability. Tetramethylguanidine Dihydrogen Phosphate stands out as a raw material for crafting ionic liquids, phase transfer catalysts, and specialty polymers. Because the guanidine group brings high basicity and low nucleophilicity, it doesn’t disrupt reactions prone to side-products or degradation. This particular feature makes it valuable in fine chemical and pharmaceutical production. Unlike many chemicals with a troublesome odor or dusting problem, Tetramethylguanidine Dihydrogen Phosphate behaves predictably in most solid handling operations – pourable as a powder, stackable as flakes, and evenly distributed when supplied as pearls or granules. Touching on density and solubility, large-scale operations can rely on accurate dosing per liter of solution. That means fewer surprises or wasted product, stretching dollars further in production environments.
Manufacturers supply detailed specs with every shipment, typically noting purity above 98%, very low residual moisture (below 0.5%), and a set melting point on quality certificates. Keeping powders dry during shipping remains a routine precaution, though as noted, this salt seldom takes on atmospheric moisture. Chemical storage experts recommend sealed containers, ambient temperatures, and low humidity; these measures stretch shelf life comfortably past a year. Techs routinely handle the compound wearing gloves and safety glasses. Compared to many chemicals in the same HS Code family, Tetramethylguanidine Dihydrogen Phosphate gives operators a break with its low volatility and manageable dust profile, so facility managers don’t dread sudden spills or airborne contamination. Even so, chemical safety data always stresses the importance of avoiding skin and eye contact, due to mild irritant potential. Inhalation and ingestion risks warrant proper engineering controls in every worksite.
Professional safety matters whether you run a small lab or a sprawling industrial plant. Tetramethylguanidine Dihydrogen Phosphate ranks as an irritant rather than a dangerous poison, so risk leans more toward discomfort and temporary symptoms than severe poisoning. Still, direct contact can cause redness and mild burning, especially in the eyes or on sensitive skin. Chemically, it’s most hazardous if mixed with strong acids or oxidizers, which can trigger rapid degradation or formation of unwanted byproducts. Used in moderation and stored correctly, it sits well within guidelines for hazardous chemical management in most countries. Speakers at chemical safety conferences remind us again and again to treat every material – even those with “lower hazard” labels – with caution and respect for PPE and emergency showers. Material safety data sheets underline environmental caution; run-off and disposal require following local rules for phosphate and nitrogen compounds, as unintended releases may contribute to eutrophication or aquatic harm.
Looking at the broader industry, smart chemists and production managers try to squeeze maximum safety, efficiency, and product quality from every batch of Tetramethylguanidine Dihydrogen Phosphate. Bulk buyers increasingly seek out sources that offer tight quality control, consistent particle size, and trustworthy certificates of analysis. Automated weighing and dispensing stations can curb exposure during transfer. Engineering upgrades, such as dust collectors or gloveboxes, help maintain cleaner work environments and reduce minor accident risk. Training operators in safe chemical handling pays off more than new hardware alone. The industry also keeps pushing toward greener manufacturing and recovery techniques. Developers focus not only on minimizing spills and improving recycling, but also on designing synthetic processes that use less phosphoric acid, generate fewer acidic byproducts, and leave behind less waste. Safe, sustainable use often comes down to day-to-day execution and honest peer review of work practices rather than grand policy statements.
Tetramethylguanidine Dihydrogen Phosphate lists a molecular weight of about 211.17 g/mol, a detail that comes up often in precise formulation work. Structural diagrams reveal a guanidine core surrounded by four methyl groups – a setup that resists unwanted reactivity. The dihydrogen phosphate moiety carries the oxygen-rich segment that links out to other ions or molecules in solution, holding the rest of the molecule stable as the reaction medium changes. In crystal form, the ions line up with hydrogen bonding and Van der Waals forces shaping the lattice, which explains why its solid state properties help with packing density, flow, and shelf-life. Laboratories who track each batch from synthesis through to final product depend on these metrics to keep quality on target – it’s not just chemical names and formulas, but molecular identity in practice that determines how well a raw material serves its market.
In my experience working with Tetramethylguanidine Dihydrogen Phosphate, reliance on consistent raw material matters as much as skill with stirring rods or pipettes. Synthetic chemists value its clean reactivity, allowing more predictable results than cheaper, less pure bases. In composite materials manufacturing, the phosphate content tunes flame retardancy and stabilizes end products, while the guanidine counterpart narrows down selectivity in polymer crosslinking reactions. Many specialty chemical companies now require suppliers to share sustainability ratings, transparency on trace impurities, and traceable batch certificates. Every pound delivered turns into thousands of dollars’ worth of finished pharmaceuticals, catalysts, or performance plastics – and that underscores just how much hinges on both the technical and ethical qualities of a single raw material. Tetramethylguanidine Dihydrogen Phosphate represents a blend of innovation and practicality, reminding industry and research that quality, safety, and utility share equal footing in today’s laboratories and production floors.
